Job Description P0A9Q7 Confidence 50.67% Date Thu Jan 5 11:11:00 GMT 2012 Rank 297 Aligned Residues 115 % Identity 16% Template c3dg8B_ PDB info PDB header:oxidoreductase, transferase Chain: B: PDB Molecule:bifunctional dihydrofolate reductase-thymidylate PDBTitle: quadruple mutant (n51i+c59r+s108n+i164l) plasmodium2 falciparum dihydrofolate reductase-thymidylate synthase3 (pfdhfr-ts) complexed with rjf670, nadph, and dump Resolution 2.58 Å

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		398	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.		.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.															460	.	.
Predicted Secondary structure																					.																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																					.																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		T	P	A	S	Q	G	G	I	G	D	L	Y	N	F	K	L	A	P	S	.	L	T	L	G	C	G	S	W	G	G	N	S	I	S	E	N	V	G	P	K	H	L	I	N	K	K	T	V	A	K	R	A	E	N	M	L	W	H	K	L	P	K	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	I	Y	F
Query Conservation																					.																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence											.	.									.		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																										.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation											.	.											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		N	N	Y	T	F	R	G	L	G	.	.	N	K	G	V	L	P	W	K	C	I	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S	L	D	M	K	Y	F	R	A	V	T	T	Y	V	N	E	S	K	Y	E	K	L	K	Y	K	R	C	K	Y	L	P	N	S	K	K	L	Q	N	V	V	V	M
Template Known Secondary structure			G	G	G						.	.	B	T	T	B		S	S	S			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																T	T	T	S								G	G	G						S
Template Predicted Secondary structure											.	.											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		33	.	.	.	.	.	.	40	.			.	.	.	.	.	.	.	.	50	.																		.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.
		463	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	R	G	S	L	P	I	A	L	D	E	V	I	T	D	G	H	K	R	A	L	I	V	T	D	R	F	L	F	N	N	G	Y	A	D	Q	I	T	S	V	L	K	A	A	G	V	E	T	E	V	F	F	E	V	E	A	D	P	T	L	S	I	V	R	K	G	A	E	L	A	N	S	F	K	P	D	V	I	I	A
Query Conservation
Alig confidence																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		G	R	T	N	W	E	S	I	P	K	K	F	K	P	L	S	N	R	I	N	V	I	L	S	R	T	L	K	K	E	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	D	F	D	E	D	V	Y	I	I	N	K	V	E	D	L	I	V	L	L	G	K	L	N	Y	Y	K	C	F	I
Template Known Secondary structure									S		S	T	T		S		T	T								S	S			T	T	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T	S		S	S	S				S	S	T	T								T	S
Template Predicted Secondary structure																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		105	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.																						.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.
		543	.	.	.	.	.	.	550	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	G	G	G	S	P	M	D	A	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	G	G	S	V	V	Y	Q	E	F
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		164	.	.	.	.	.	170	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions