|   |
428 | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | A | K | A | I | D | G | Y | T | P | R | D | Y | L | T | H | W | L | S | Q | W | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
R | D | Y | G | I | D | G | F | R | V | D | T | A | K | H | V | E | L | P | A | W | Q | Q | L | K | T | E | A | S | A | A | L | R | E | W | K | K | A | N | P | D | K | A | L | D | D | K | P | F |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |
|
| . | . | . | . | . | . | . | . | . |   |   |   |
|
|
|
|
|
|
|
|   |
|   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|   |
|   |
|   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|   |
|
| . | . | . | . | . |
|   |   |   |
|   |   |
|
|
|   |
|
Template Sequence |   |
N | D | I | D | N | S | N | P | V | V | Q | A | E | E | L | N | W | L | Y | Y | L | M | N | F | G | T | I | T | G | N | N | P | E | A | N | F | D | G | I | R | V | N | A | V | D | N | V | D | V | D | L | L | S | I | A | R | D | Y | F | N | A | A | Y | . |
. |
. |
. |
. |
N | M | E | Q | S | D | A | S | A | N | K | H |
Template Known Secondary structure |   |
 |  |  |
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  | S |
| T | T | S |
|
|
|  |  |  |  | T | T | G | G | G | S |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
| T | T | S |
|  |  |  |  | T | T | S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
984 | . | . | . | . | . | 990 | . | . | . | . | . | . | . | . | . | 1000 | . | . | . | . | . | . | . | . | . | 1010 | . | . | . | . | . | . | . | . | . | 1020 | . | . | . | . | . | . | . | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 1050 | . | . | . | . | . | . | . | . |
  |
  |   |
499 | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 560 | . | . | . | . | . | |
|
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
| . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
Query Sequence |   |
W | M | T | G | E | A | W | G | H | G | V | M | Q | S | D | Y | Y | R | H | G | F | D | A | M | I | N | F | D | Y | Q | E | Q | A | A | K | A | V | D | C | L | A | Q | M | D | T | T | W | Q | Q | M | A | E | K | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | G | F | N | V | L | S | Y | L | S | S | H | D | . |
. |
Query Conservation |   |
  |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|
|   |
|
|
| . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
|
|
|
|
|   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|   |
|
|   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |
|
|
|
|
|
|   |
|   |
|
|   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
Template Sequence |   |
I | N | I | L | E | D | W | G | W | D | D | P | A | Y | V | N | K | I | G | N | P | Q | L | T | M | D | D | R | L | R | N | A | I | M | D | T | L | S | G | A | P | D | K | N | Q | A | L | N | K | L | I | T | Q | S | L | V | N | R | A | N | D | N | T | E | N | A | V | I | P | S | Y | N | F | V | R | A | H | D | S | N |
Template Known Secondary structure |   |
|
|  |  |
|
|
|
| T | T |  |  |  |  |  |  |  | T | T |
| S | S | B |  |  |
|  |  |  |  |  |  |  |  |  |  | T | S | S |
| T | T | T |
|
|
| T | T |  |  |  |  | S | S | S | S |
|
| S |  |  |
|
| S | S |
| S |
|
|  |  |  |  | S |
|
| S | S | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1059 | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080 | . | . | . | . | . | . | . | . | . | 1090 | . | . | . | . | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | 1120 | . | . | . | . | . | . | . | . | . | 1130 | . | . | . | . | . | . | . | . |
  |
  |   |
|
566 | . | . | . | 570 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 580 | . | . | . | |
. | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . |
Predicted Secondary structure |   |
. |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
. |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
T | R | L | F | R | E | G | G | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | A | A | E | L | L | L | L | A | . |
P | G | A | V | Q | I | F | Y | G | D | E | S | S | R | P | F | G | P | T | G | S |
Query Conservation |   |
. |   |   |
|   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |
|
|
|   | . |
|
|
|
|   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|
|
|
|   |
|
|
|   |
|   |   |   |
|   |
|
|
|   |   |
|
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
Template Sequence |   |
A | Q | D | Q | I | R | Q | A | I | Q | A | A | T | G | K | P | Y | G | E | F | N | L | D | D | E | K | K | G | M | E | A | Y | I | N | D | Q | N | S | T | N | K | K | W | N | L | Y | N | M | P | S | A | Y | T | I | L | L | T | N | K | D | S | V | P | R | V | Y | Y | G | D | L | Y | Q | D | G | G | Q | Y | M | E | H |
Template Known Secondary structure |   |
T |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | S | S |
| S | S | S |
| S |
|  |  |  |  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  | G | G | G | T | B |
| S | S | B | S | T | T |
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|  |  |
|
|
|
|
|  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1139 | 1140 | . | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | . | . | 1180 | . | . | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | . | 1200 | . | . | . | . | . | . | . | . | . | 1210 | . | . | . | . | . | . | . | . |
  |
  |   |
605 | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 670 |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
D | P | L | Q | G | T | R | S | D | M | N | W | Q | D | V | S | G | K | S | A | A | S | V | A | H | W | Q | K | I | S | Q | F | R | A | R | H | P | A | I | G | A | G | K | Q | T | T | L | L | L | K | Q | G | Y | G | F | V | R | E | H | G | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | K | V | L | V |
Query Conservation |   |
|   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|   |   |
|
|
|   |   |
|
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |
|
|   |
|   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|
|
|
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|   |
|
|
|
|
|
|   |
|
|
|
| . | . |
|
|
|
|
|   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |
|   |
|
|   |   |
|
|
|
|
|
|   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
K | T | R | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | D | T | I | T | N | L | L | K | T | R | V | K | Y | V | A | . |
. |
G | G | Q | T | M | S | V | D | K | N | G | I | L | T | N | V | R | F | G | K | G | A | M | N | A | T | D | T | G | T | D | E | T | R | T | E | G | I | G | V |
Template Known Secondary structure |   |
. | . | . | . | . | . | B |
| T | T | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | S |
|  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |
|
| T | T |
| S | S | T | T |
|
|
|
| T | T | T | T | T |
|
|  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . |
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
1219 | 1220 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 1230 | . | . | . | . | . | . | . | . | |
|
. | 1240 | . | . | . | . | . | . | . | . | . | 1250 | . | . | . | . | . | . | . | . | . | 1260 | . | . | . | . | . | . | . | . | . | 1270 | . | . | . | . | . | . | . | . |
  |
  |   |
671 | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
Query Sequence |   |
V | W | A | G | Q |
Query Conservation |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|
Template Sequence |   |
V | I | S | N | N |
Template Known Secondary structure |   |
 |  |  |
|
|
Template Predicted Secondary structure |   |
 |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
  |   |
1279 | 1280 | . | . | . |
  |