|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | |
|
|
. | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |
|
|
|  |  |  |  |
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
L | R | I | A | D | K | T | F | D | S | H | L | F | T | G | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | K | F | A | S | S | Q | L | M | V | E | A | I | R | . |
. |
. |
A | S | G | S | Q | L | V | T | L | A | M | K | R | V | D | L | R | Q | H | N | D | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|   |
|   |
|   |   |
|   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |
|   |   |
|   |   | . | . | . |
|   |
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |
|
|   |   |   |
|
|
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|
|   |
|
|
|
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
Template Sequence |   |
I | K | I | G | N | N | E | L | L | H | R | A | V | I | P | P | L | T | R | M | R | A | L | H | P | G | N | I | P | N | R | D | W | A | V | E | Y | Y | T | Q | R | A | Q | R | P | G | T | M | I | I | T | E | G | A | F | I | S | P | Q | A | G | G | Y | D | N | A | P | G | V | W | S | E | E | Q | M | V | E | W | T | K |
Template Known Secondary structure |   |
 |  |  | T | T |  |  |  | S | S | S |  |  | B |
|
|
|
|
|
|
|
| B | T | T | T | T | B |
|
| T | T | T |  |  |  |  |  |  |  |  | T |
| S | T | T |
|  |  |  |  |  |  |  |  | S | S | G | G | G |
|
|
| T | T | S |
| B | S | S | S |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . |
  |
  |   |
54 | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | L | E | P | L | I | A | A | G | V | T | L | L | P | N | T | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | A | K | T | A | E | E | A | I | F | A | A | H | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |
|
|   |   |
|   |   |
|   |   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|   |   |
|
|   |   |
Template Sequence |   |
I | F | N | A | I | H | E | K | K | S | F | V | W | V | Q | L | W | V | L | G | W | A | A | F | P | D | N | L | A | R | D | G | L | R | Y | D | S | A | S | D | N | V | F | M | D | A | E | Q | E | A | K | A | K | K | A | N | N | P | Q | H | S | L | T | K | D | E | I | K | Q | Y | I | K | E | Y | V | Q | A | A | K | N |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |
|
| G | G | G | S |
|  |  |  |  |  |  | T | T |
|
|  |  |  | S |
| S | S |
|
| S |
|  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . |
  |
  |   |
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | |
. | . | . | . | . | . | . | . | . | 130 | . | . | . | |
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
A | R | E | A | L | G | T | N | W | L | K | L | E | I | H | P | D | A | R | W | L | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | D | P | I | E | T | L | K | A | A | E | T | L | V | . |
Q | Q | G | F | V | V | L | P | Y | C | G | A | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |
|   |
|   |
|   |
|   |
|   |   |   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |
|   |
|   |
|   |   |   |   |   | . |   |   |
|   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|   |   |
| . |
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |
|
|
|
|
|   |
|
|   |
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|
|
|   |
|
|
|   |   |
|
|   |   |   |
|   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
S | I | A | A | . |
G | A | D | G | V | E | I | H | S | A | N | G | Y | L | L | N | Q | F | L | D | P | H | S | N | T | R | T | D | E | Y | G | G | S | I | E | N | R | A | R | F | T | L | E | V | V | D | A | L | V | E | A | I | G | H | E | K | V | G | L | R | L | S | P | Y | G | V | F | N | S | M | S | G | G | A | E |
Template Known Secondary structure |   |
 |  |  | T | . | T |
| S |  |  |  |  |  |
|
| T | T | S |  |  |  |  |  |  |
| T | T | T |
|
|
|
| S | T | T | S | S | S |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G |  |  |  |  |  |
| T | T |
|
| T | T | T |
|
| G | G | G | S |
Template Predicted Secondary structure |   |
 |  |  |
| . |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|  |  |  |
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
180 | . | . | . | |
. | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
134 | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
P | V | L | C | K | R | L | E | E | V | G | C | A | A | V | M | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | G | A | P | I | G | S | N | Q | G | L | E | T | R | A | M | L | E | I | I | I | Q | Q | A | T | V | P | V | V | V | D | A | G | I | G | V | P | S | H | A | A | Q | A | L | E | M |
Query Conservation |   |
. | . | . | . | . | . | . |   |   |   |
|
|   |   |   |   |
|
|
|
|   |
|   |
| . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|
|
|   |   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
T | G | I | V | A | Q | Y | A | Y | V | A | G | E | L | E | K | R | A | K | A | G | K | R | L | A | F | V | H | L | V | E | P | R | V | T | N | P | F | L | T | E | G | E | G | E | Y | E | G | G | S | N | D | F | V | Y | S | I | W | K | G | P | V | I | R | A | G | N | F | A | L | H | P | E | V | V | R | E | E | V | K |
Template Known Secondary structure |   |
T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| S |  |  |  |  |  |
| T | T |
| S |
| T | T | S |
| T | T | S | S |
|
|
| S |
|
| T | T |  |  |  |  |  |
|
| S |
|  |  |  |  | S | S |
| T | T |
|  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
259 | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . |
  |
  |   |
197 | |
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
| . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | . |
A | D | A | V | L | V | N | T | A | I | A | V | A | D | D | P | V | N | M | A | K | A |
Query Conservation |   |
| . |
|
|   |
|   |
|
|
|
|
|   |   |   |   |
|
|   |   |   |   |   |   |
Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |
|   |   |   |
|   |   |
|
|
|
|
|   |   |   |
|   |   |   |
Template Sequence |   |
D | K | R | T | L | I | G | Y | G | R | F | F | I | S | N | P | D | L | V | D | R | L | E | K |
Template Known Secondary structure |   |
S | T | T |  |  |  |  |
|
|  |  |  |  |  |
| T | T |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
339 | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . |
  |