Job Description P30139 Confidence 99.91% Date Thu Jan 5 11:46:05 GMT 2012 Rank 18 Aligned Residues 223 % Identity 14% Template c2fptA_ PDB info PDB header:oxidoreductase Chain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial; PDBTitle: dual binding mode of a novel series of dhodh inhibitors Resolution 2.40 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		3	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.
Predicted Secondary structure																																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		R	I	A	D	K	T	F	D	S	H	L	F	T	G	T	G	K	F	A	S	S	Q	L	M	V	E	A	I	R	A	S	G	S	Q	L	V	T	L	A	M	K	R	V	D	L	R	Q	H	N	D	A	I	L	E	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																	.																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																	.
Template Sequence		R	V	L	G	H	K	F	R	N	P	V	G	I	A	A	.	G	F	D	K	H	G	E	A	V	D	G	L	Y	K	M	G	F	G	F	V	E	I	G	S	V	T	P	K	P	Q	E	G	N	P	R	P	R	V	F	R	L	P	E	D	Q	A	V	I	N	R	Y	G	F	N	S	H	G	L	S	V	V	E	H	R
Template Known Secondary structure				T	T				S	S	S					T	.	T	T	T	T	T	S	S								T	T		S									S	S		B			S		S							G	G	G	T										B
Template Predicted Secondary structure																	.
Template SS confidence
		82	.	.	.	.	.	.	.	90	.	.	.	.	.	.		.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160
											57	.	.	60	.	.	.	.	.	.	.	.	.			70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.														110	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.														.	.																																									.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.														.	.																																									.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	P	L	I	A	A	G	V	T	L	L	P	N	T	.	.	S	G	A	K	T	A	E	E	A	I	F	A	A	H	L	A	R	E	A	L	G	T	N	W	L	K	L	E	I	H	P	D	A	R	W	L	L	P	D	P	.	.	.	.	.	.	.	.	.	.	.	.	.	I	E	T
Query Conservation		.	.	.	.	.	.	.	.	.														.	.																																									.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.														.	.																																									.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		L	R	A	R	Q	Q	K	Q	A	K	L	T	E	D	G	L	P	L	G	V	N	L	G	K	N	K	T	S	V	D	A	A	E	D	Y	A	E	G	V	R	V	L	G	P	L	A	D	Y	L	V	V	N	V	S	S	P	N	T	A	G	L	R	S	L	Q	G	K	A	E	L	R	R	L	L	T	K	V	L	Q	E
Template Known Secondary structure				T	T										T	T											T	T		S														G	G	G		S									T	T	S	T	T	S	G	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		161	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
		113	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.					.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.																			.	.	.	.	.	.	170
Predicted Secondary structure																							.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																							.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		L	K	A	A	E	T	L	V	Q	Q	G	F	V	V	L	P	Y	C	G	A	D	.	.	.	.	P	V	L	C	K	R	L	E	E	V	G	C	A	A	V	M	P	L	G	A	P	I	G	S	N	Q	G	L	E	T	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	R	A	M	L	E	I	I
Query Conservation																							.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																							.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		R	D	G	L	R	R	V	H	R	P	A	V	L	V	K	I	A	P	D	L	T	S	Q	D	K	E	D	I	A	S	V	V	K	E	L	G	I	D	G	L	I	V	T	N	T	T	V	S	R	P	A	G	L	Q	G	A	L	R	S	E	T	G	G	L	S	G	K	P	L	R	D	L	S	T	Q	T	I	R	E	M
Template Known Secondary structure				T	S		G	G	G										S																		T										B	S				T	T				T	T	T	T	S	S	S
Template Predicted Secondary structure
Template SS confidence
		241	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320
		171	.	.	.	.			.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.			.	.	.	.	.	.	.	220	.	.	.	.	.	.
Predicted Secondary structure							.	.																																						.	.
Query SS confidence							.	.																																						.	.
Query Sequence		I	Q	Q	A	T	.	.	V	P	V	V	V	D	A	G	I	G	V	P	S	H	A	A	Q	A	L	E	M	G	A	D	A	V	L	V	N	T	A	I	A	V	A	D	D	.	.	P	V	N	M	A	K	A	F	R	L	A	V	E	A
Query Conservation							.	.																																						.	.
Alig confidence							.	.																																						.	.
Template Conservation
Template Sequence		Y	A	L	T	Q	G	R	V	P	I	I	G	V	G	G	V	S	S	G	Q	D	A	L	E	K	I	R	A	G	A	S	L	V	Q	L	Y	T	A	L	T	F	W	G	P	P	V	V	G	K	V	K	R	E	L	E	A	L	L	K	E
Template Known Secondary structure					T	T	T		S						S	S			S											T		S					S								T
Template Predicted Secondary structure
Template SS confidence
		321	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions