|   |
353 | . | . | . | . | |
. | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | |
|
|
|
|
|
. | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | 400 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
| . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | G | V | N | R | . |
H | E | H | H | P | L | H | G | Q | V | M | D | E | Q | T | M | . |
. |
. |
. |
. |
. |
V | Q | D | I | L | L | M | K | Q | N | N | F | N | A | V | R | C | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | H | Y | P | N | H | P | L | . |
. |
. |
. |
. |
. |
. |
W | Y | T | L | C | D | R | Y | G |
Query Conservation |   |
|
|
|
|   | . |
|   |   |   |
|   |   |
|   |   |   |   |   |
|   |   | . | . | . | . | . | . |   |   |
|
|   |
|
|
|   |   |
|   |
|   |
|
|   | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|   |   |   |   | . | . | . | . | . | . | . |
|
|
|
|
|
|
|   |
|
Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |
|
Template Sequence |   |
A | G | W | N | L | G | N | Q | L | E | A | A | V | N | G | T | P | N | E | T | A | W | G | N | P | T | V | T | P | E | L | I | K | K | V | K | A | A | G | F | K | S | I | R | I | P | V | S | Y | L | N | N | I | G | S | A | P | N | Y | T | I | N | A | A | W | L | N | R | I | Q | Q | V | V | D | Y | A | Y | N | E | G |
Template Known Secondary structure |   |
S |  |  |  |  |
| S | S | T | T |
|  |  | T | T |  |  |
| T | T | T | T | S |
|
|
|
|
|  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
|
|
|
| G | G | G | B |
|
| T | T | T |
|
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
Template Predicted Secondary structure |   |
|
|  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
44 | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . |
  |
  |   |
408 | . | 410 | . | . | . | . | |
|
|
|
. | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
Query Sequence |   |
L | Y | V | V | D | E | A | . |
. |
. |
. |
N | I | E | T | H | G | M | V | P | M | N | R | L | T | D | D | P | R | W | L | P | A | M | S | E | R | V | T | R | M | V | Q | R | D | R | N | H | P | S | V | I | I | W | S | L | G | N | E | S | G | H | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | N | H |
Query Conservation |   |
|   |
|   |
|
|
| . | . | . | . |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | Y | V | I | I | N | I | H | G | D | G | Y | N | S | V | Q | G | G | W | L | L | V | N | G | G | N | Q | T | A | I | K | E | K | Y | K | K | V | W | Q | Q | I | A | T | K | F | S | N | Y | N | D | R | L | I | F | E | S | M | N | E | V | F | D | G | N | Y | G | N | P | N | S | A | Y | Y | T | N | L | N | A | Y | N |
Template Known Secondary structure |   |
|  |  |  |  |
|
|
| G | G | G |
| T | T | S | T | T |
|
|
|
| T | T |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
| T | T |  |  |  |  |
|
| S | S |
|
|
| S |
|
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
124 | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . |
  |
  |   |
470 | . | . | . | . | . | . | . | . | . | |
|
|
480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | |
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
D | A | L | Y | R | W | I | K | S | V | . |
. |
. |
D | P | S | R | P | V | Q | Y | E | G | G | G | A | D | T | T | A | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | I | I | C | P | M | Y | A | R | V | D | E | D | Q | P | F | P | A | V | P | K | W | . |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   | . | . | . |
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Q | I | F | V | D | T | V | R | Q | T | G | G | N | N | N | A | R | W | L | L | V | P | G | W | N | T | N | I | D | Y | T | V | G | N | Y | G | F | T | L | P | T | D | N | Y | R | S | S | A | I | P | S | S | Q | K | R | I | M | I | S | A | H | Y | Y | S | P | W | D | F | A | G | E | E | N | G | N | I | T | Q | W | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | S | S | G | G | G | G | T | S |
|  |  |  |  |
| G | G | G |
|  |  |  |  |  | S | S | S | S |
|
|
|
|
|
| T | T | S |
| T | T | S |
| T | T |
|
|
|  |  |  |  |  |  |  |
|
| S |  |  |  |  | T |
| S | S | S | S |
|
| B |
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
204 | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | I | K | K | W | L | S | L | P | G | E | T | R | P | L | I | L | C | E | Y | A | H | A | M | G | N | S | L | G | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
F | A | K | Y | W | Q | A | F | R | Q | Y | P | R | L | Q | G | G | F | V | W |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|
|   |
|
|
|
|
|   |   |
|   | . | . | . | . | . | . | . | . | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |
| . | . |   |   |   |   |   |
|
Template Sequence |   |
A | T | S | T | N | P | A | K | K | S | T | W | G | Q | E | D | Y | L | E | S | Q | F | K | S | M | Y | D | K | F | V | T | Q | G | Y | P | V | V | I | G | E | F | G | S | I | D | K | T | S | Y | D | S | S | N | N | V | Y | R | A | A | Y | A | K | A | V | T | A | K | A | K | K | Y | K | . |
. |
M | V | P | V | Y | W |
Template Known Secondary structure |   |
T | T |
| S |
| G | G | G | B |
| S | S |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | G | G | G | T |
|
|  |  |  |  |  |  |
|
|
|
|
| T | T | T |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . | . |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
284 | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | |
|
. | . | . | . | 360 | . |
  |
  |   |
570 | . |
Predicted Secondary structure |   |
 |  |
Query SS confidence |   |
|
|
Query Sequence |   |
D | W |
Query Conservation |   |
  |   |
Alig confidence |   |
|
|
Template Conservation |   |
  |   |
Template Sequence |   |
D | N |
Template Known Secondary structure |   |
 |
|
Template Predicted Secondary structure |   |
|
|
Template SS confidence |   |
|
|
  |   |
362 | . |
  |