|   |
352 | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | |
|
|
|
|
|
|
. | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . |
|
|
|
| . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | R | G | V | N | R | H | E | H | H | P | L | H | G | Q | V | M | D | E | Q | T | M | V | Q | D | I | L | L | M | K | Q | N | N | F | N | A | V | R | C | . |
. |
. |
. |
. |
. |
. |
S | H | Y | P | . |
. |
. |
. |
. |
. |
. |
. |
N | H | P | L | W | Y | T | L | C | D | R | Y | G | L | Y | V | V | D | E | A | N | I |
Query Conservation |   |
|
|
|
|
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |
|
|   |
|
|
|   |   |
|   |
|   |
|
|   | . | . | . | . | . | . | . |
|
|
|
| . | . | . | . | . | . | . | . |   |   |   |   |
|
|
|
|
|
|
|   |
|
|   |
|   |
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |
| . | . |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |   |   |
|   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |
Template Sequence |   |
L | A | E | A | F | R | D | Y | F | . |
. |
P | I | G | A | A | I | E | P | G | Y | T | T | G | Q | I | A | E | L | Y | K | K | H | V | N | M | L | V | A | E | N | A | M | K | P | A | S | L | Q | P | T | E | G | N | F | Q | W | A | D | A | D | R | I | V | Q | F | A | K | E | N | G | M | E | L | R | F | H | T | L | V |
Template Known Secondary structure |   |
 |  |  |  | T | T | T | T |
| . | . |
|  |  |  |  |  |
| G | G | G | S | S |  |  |  |  |  |  |  |  |  |  |
| S |  |  |  |  | S | S | T | T | S |  |  |  |  |
| S | B | T | T | B |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
| . | . |  |  |  |  |  |  |
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
47 | . | . | 50 | . | . | . | . | . | |
|
. | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . |
  |
  |   |
417 | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
E | T | H | G | M | V | P | M | N | R | L | T | D | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | R | W | L | P | A | M | S | E | R | V | T | R | M | V | Q | R | D | R | N | H | P | S | V | I | I | W | S | L | G | N | E | S | G | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |
|   | . | . |
|   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
W | H | N | Q | T | P | D | W | F | F | L | D | K | E | G | K | P | M | V | E | E | T | D | P | Q | K | R | E | E | N | R | K | L | L | L | Q | R | L | E | N | Y | I | R | A | V | V | L | R | Y | K | D | D | . |
. |
I | K | S | W | D | V | V | N | E | V | I | E | P | N | D | P | G | G | M | R | N | S | P | W | Y | Q |
Template Known Secondary structure |   |
 | S | S | S |
|
| G | G | G | G | B |
| T | T | S | S | B | G | G | G |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | . | . |
|
|  |  |  |  |  |  |
|
| B |
| T | T | S | G | G | G | B |
|
|
|  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
125 | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | |
|
. | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . |
  |
  |   |
|
|
|
466 | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . |
Predicted Secondary structure |   |
. | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
G | A | N | H | D | A | L | Y | R | W | I | K | S | V | D | P | S | R | P | V | Q | Y | E | G | G | G | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | T | T | A | T | D | I | I | C | P | M | Y | A | R | V | D | E | D | Q | P | F | P | A | V | P | K | W | S | I | K | K |
Query Conservation |   |
. | . | . |
|   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|   |
|
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |
|
|   |   |   |
| . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | T | G | T | E | Y | I | E | V | A | F | R | A | T | R | E | A | G | G | S | D | I | K | L | Y | I | N | D | Y | N | T | D | D | P | V | K | R | D | I | L | Y | E | L | V | K | N | L | L | E | K | G | V | P | I | D | G | V | G | H | Q | T | H | . |
. |
. |
. |
I | D | I | Y | N | P | P | V | E | R | I | I | E | S |
Template Known Secondary structure |   |
 |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | S |  |  |  |  |  |  | S |
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |  |
|
|  | . | . | . | . |  |  | S | S |
| S |
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
203 | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | |
|
|
|
. | . | . | . | . | 270 | . | . | . | . | . | . | . | . |
  |
  |   |
524 | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
550 | . | . | . | . | . | . | . | . | . | 560 | |
. | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | L | S | L | P | G | E | T | R | P | L | I | L | C | E | Y | A | H | A | M | G | N | S | L | G | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | A | K | Y | W | Q | A | F | R | Q | Y | . |
P | R | L | Q | G | G | F | V | W | D | W | V | D | Q | S | L | I | K | Y | D | E | N | G | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|   |   |
|
|   |
|
|
|
|
|   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |
|
|   |   |   |   |   |   | . |   |   |   |   |
|
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |   |
| . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
I | K | K | F | A | G | L | G | L | D | N | I | I | T | E | L | D | M | S | I | Y | S | W | N | D | R | S | D | Y | G | D | S | I | P | D | Y | I | L | T | L | Q | A | K | R | Y | Q | E | L | F | D | A | L | K | E | N | K | D | I | V | S | A | V | V | F | W | G | I | S | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  | T | T | T |
|  |  |  |  |  |  |  |  |  |  | S | S |
| T | T |
|
|
|
|
|
| S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | G | G | G |  |  |  |  |  |  | S |
| S | B | T | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
279 | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
  |
  |   |
585 | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | W | S | A | Y | G | G | D | F | G | D | T | P | N | D | R | Q | F | C | M | N | G | L | V | F | A | D | R | T | P | H | P | A | L | T | E | A | K |
Query Conservation |   |
  |   |   |   |
|
|
|
|
|
|
|   |
|   |
|   |
|
|   |   |   |
|
|
|   |   |
|
|   |
|
|
|   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |
|
|   |
|   |
|   |   |
|
|
|
|   |   |
|   |   |
Template Sequence |   |
K | Y | S | W | L | N | G | F | P | V | K | R | T | N | A | P | . |
. |
. |
. |
. |
L | L | F | D | R | N | F | M | P | K | P | A | F | W | A | I | V |
Template Known Secondary structure |   |
T | S |
| G | G | G | T | S | S | S | S | S |
|
|
|
| . | . | . | . | . | S | S | B |
| T | T | S |
| B |
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
348 | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 |
  |