|   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | A | V | P | M | E | Q | V | V | R | I | H | A | S | S | G | T | T | G | K | P | T | V | V | G | Y | T | Q | N | D | I | D | N | W | A | N | I | V | A | R | S | L | R | A | A | G | G | S | P | K | D | K | I | H | V | A | Y | G | Y | G | L | F | T | G | G | L | G | A | H | Y | G | A | E | R | L | G | A | T | V | I |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|   |
|
|   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | S | F | N | L | D | D | I | A | S | I | M | F | T | S | G | T | T | G | P | Q | K | A | V | P | Q | T | F | R | N | H | Y | A | S | A | I | G | C | K | E | S | L | . |
. |
. |
. |
G | F | D | R | D | T | N | W | L | S | V | L | P | I | Y | H | I | S | G | L | S | V | L | L | R | A | V | I | E | G | F | T | V | R |
Template Known Secondary structure |   |
|
|
|
| T | T | S |  |  |  |  |  |  |
|
| S | S | S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | . | . |
|
|
| T | T |
|  |  |  |  |
| S |
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
156 | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | |
|
|
|
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . |
  |
  |   |
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | M | S | G | G | Q | T | E | K | Q | A | Q | L | I | R | D | F | Q | P | D | M | I | M | V | T | P | S | Y | C | L | N | L | I | E | E | L | E | R | Q | L | G | G | D | A | S | G | C | S | L | R | V | G | V | F | G | A | E | P | W | T | Q | A | M | R | K | E | I | E | R | R | L | G | I | T | A | L | D | I | Y | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
I | V | D | K | F | N | A | E | Q | I | L | T | M | I | K | N | E | R | I | T | H | I | S | L | V | P | Q | T | L | N | W | L | M | Q | . |
. |
. |
. |
. |
. |
Q | G | L | H | E | P | Y | N | L | Q | K | I | L | L | G | G | A | K | L | S | A | T | M | I | E | T | A | L | Q | Y | . |
N | L | P | I | Y | N | S | F | G |
Template Known Secondary structure |   |
 |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |  | T |
|
| S |
| T | T |
|
|  |  |  |  |
| S | S |
|
|
|  |  |  |  |  |  |  |  |  | T | . | T |
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . |
|
|
|  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
232 | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | |
|
|
|
|
|
. | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | |
. | . | . | . | 300 | . | . | . | . |
  |
  |   |
240 | . | . | . | . | . | . | . | . | . | 250 | . | |
|
|
. | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
Query Sequence |   |
L | S | E | V | M | G | P | G | V | A | M | E | . |
. |
. |
C | L | E | T | T | D | G | P | T | I | W | E | D | H | F | Y | P | E | I | V | N | P | H | D | G | T | P | L | A | D | G | E | H | G | E | L | L | F | T | T | L | T | K | E | A | L | P | V | I | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | R | T | R |
Query Conservation |   |
  |
|
|   |
|   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|   |   |   |   |   |   |   |
|   |   |
| . | . | . | . | . | . | . | . | . | . | . |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . |   |   |
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
M | T | E | T | C | S | Q | F | L | T | A | T | P | E | M | L | H | A | R | P | D | T | V | G | M | P | S | A | N | V | D | V | K | I | K | N | P | . |
. |
. |
. |
. |
. |
N | K | E | G | H | G | E | L | M | I | K | G | A | N | V | M | N | G | Y | L | Y | P | T | D | L | T | G | T | F | E | N | G | Y | F | N | T | G |
Template Known Secondary structure |   |
 | G | G | G | T |  |  |  |  |  |  |
|  |  |  |  |  |  |
| T | T |  |  |  |  |  |
| T | T |
|  |  |  |  |  | S |
| . | . | . | . | . | . |
| S | S | S |
|  |  |  |  |  |  | S | T | T | S |
| S |
|
| S | B |
| S |
|
|
|
|
|  |  | T | T |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
| . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
305 | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . |
  |
  |   |
306 | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | L | T | R | L | L | P | G | T | A | R | T | M | R | R | M | D | R | I | S | G | R | S | D | D | M | L | I | I | R | G | V | N | V | F | P | S | Q | L | E | E | E | I | V | K | F | E | H | L | S | P | H | Y | Q | L | E | V | N | R | R | G | H | L | D | S | L | S | V | K | V | E | L | K | E | S | S | L | T | L | T |
Query Conservation |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |
|
|   |   |
|   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
|   |   |   |   |   |   |   |
| . | . | . | . | . | . |   |
|   |   |   |
|
|   |
|
|   |
|
|   |   |
|   |   |
|   |
|   |
|
|
|   |   |
|   |   |   |
|   |
|   |   |
|   |
|   |
|   |   |   |   |   |   |
|   |   |
|   |
|   |
|
|   |   |   |   |   |   | . | . | . |
Template Sequence |   |
D | I | A | E | I | D | H | E | G | . |
. |
. |
. |
. |
. |
Y | V | M | I | Y | D | R | R | K | D | L | I | I | S | G | G | E | N | I | Y | P | Y | Q | I | E | T | V | A | K | Q | F | P | G | I | S | D | A | V | C | V | G | H | P | D | D | T | W | G | Q | V | P | K | L | Y | F | V | S | E | S | D | I | S | . |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |
| T | T |
| . | . | . | . | . | . |
|  |  |  |  |
|
|
|
| S |
|  |  |  | T | T |  |  |  |
|  |  |  |  |  |  |  |  |  |  | S | T | T |  |  |  |  |  |  |  |  |  |  |
| S | S | S | S |  |  |  |  |  |  |  |  |  | S | S |
|
|
| . | . | . |
Template Predicted Secondary structure |   |
|
|  |  |  |
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
379 | 380 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | |
|
|
  |
  |   |
386 | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | E | Q | R | C | Q | V | C | H | Q | L | R | H | R | I | K | S | M | V | G | I | S | T | D | V | M | I | V | N |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
. | . | . |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|   | . |   |   |   |   |
|
|
Template Sequence |   |
. |
. |
. |
K | A | Q | L | I | A | Y | L | S | K | H | L | A | K | Y | K | V | P | K | . |
H | F | E | K | V | D |
Template Known Secondary structure |   |
. | . | . |  |  |  |  |  |  |  |  |  |  |  | S |
| T | T | T | S |
| S | . |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
. | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
| . |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | |
. | 470 | . | . | . | . |
  |