|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | |
. | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | |
|
|
. | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
| . |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . |  |  |  |  |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | K | V | G | I | N | G | F | G | R | I | G | R | L | V | L | G | R | L | L | E | V | K | S | N | I | D | V | V | A | I | N | D | L | T | . |
S | P | K | I | L | A | Y | L | L | K | H | D | S | N | Y | G | P | F | P | W | S | . |
. |
. |
V | D | F | T | E | D | S | L | I | V | D | G | K | S | I | A | V | Y | A | E |
Query Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|
|   |   |   |   |
|
|
|
|
|
|
|
|   |   | . |   |   |   |   |   |
|
|
|
|   |   |
|
|   |   |
|   |   |   |   |   | . | . | . |
|   |   |   |   |   |   |
|   |
|   |
|   |   |
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |
|
|
|
|
|
|
|
|
|   |
|   |
|
|
|   | . |   |   |   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | K | V | L | I | N | G | Y | G | S | I | G | K | R | V | A | D | A | V | S | . |
M | Q | D | D | M | E | V | I | G | V | T | K | T | K | P | D | F | E | A | R | L | A | V | E | K | G | Y | K | L | F | V | A | I | P | D | N | E | R | V | K | L | F | E | D | A | G | I | P | V | E | G | T | I | L | D | I | I | E | D |
Template Known Secondary structure |   |
 |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  | . |  | S | S | S |  |  |  |  |  |  |  |  | S | S |
| S |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  | S | S |
|
|  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
| B | G | G | G | T | G | G | G |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | |
. | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
  |
  |   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | |
|
|
. | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
| . | . | . |
|
|
|
|  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | E | A | K | N | I | P | W | K | A | K | G | A | E | I | I | V | E | C | T | G | F | Y | T | S | A | E | K | S | Q | A | H | L | D | A | G | A | K | K | V | L | I | S | A | P | A | . |
. |
. |
G | E | M | K | T | I | V | Y | N | V | N | D | D | T | L | D | G | N | D | T | I | V | S | V | A | S | C | T | T | N | C |
Query Conservation |   |
  |   |
|   |   |
|   |
|   |   |   |
|
|
|
|
|
|
|   |
|
|   |
|   |   |   |   |   |
|   |   |
|
|   |
|
|
|
|   |
|
|
|
|
|
|   | . | . | . |   |
|
|
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|
|   |   |   |   |   | . |   |   |   |
|
|
|
|
|
|
|
|
|   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | D | I | V | V | D | G | A | P | K | K | I | G | K | Q | N | L | E | N | I | Y | K | P | H | K | V | K | A | I | L | Q | G | G | E | K | A | K | D | V | E | D | N | F | N | A | L | W | S | Y | N | R | C | Y | . |
G | K | D | Y | V | R | V | V | S | C | N | T | T | G |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |
| S |  |  |  |  |
|
|
| T | T |  |  |  |  |  |  |  |  | T | T | T | T | T | T |
|  |  |  |  |
| T | T | S |
| G | G | G | S | S |  |  |  |
| T | T | T | T | T | T | T | T | T | . | T |
| S |  |  |  |  |
|
|  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |
| . |
|
|
|  |  |  |
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | |
. | . | . | . | . | 140 | . | . | . | . | . | . | . | . |
  |
  |   |
155 | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | A | P | M | A | K | A | L | H | D | S | F | G | I | E | V | G | T | M | T | T | I | H | A | Y | T | G | T | Q | S | L | V | D | G | P | R | G | K | D | L | R | A | S | R | A | A | A | E | N | I | I | P | H | T | T | G | A | A | K | A | I | G | L | V | I | P | E | L | S | G | K | L | K | G | H | A | Q | R | V | P |
Query Conservation |   |
|
|
|   |
|
|   |
|   |   |   |
|
|
|   |   |   |   |
|
|
|
|
|
|   |
|   |   |
|   |   |   |
|   |   |   |   |   |
|   |
|   |   |
|
|   |   |   |
|
|
|
|   |   |
|
|   |
|
|   |
|   |   |
|
|
|   |
|   |
|
|
|   |
|   |
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|   |
|
|   |   |   |
|
|
|   |   |   |   |
|
|
|   |   |
|   |
|
|   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |
|
|
|   |   |   |
|
|
|
|
|
Template Sequence |   |
L | C | R | I | L | Y | A | I | N | S | I | A | D | I | K | K | A | R | I | V | L | V | R | R | A | A | D | P | N | D | D | K | T | G | P | V | . |
. |
. |
. |
. |
. |
. |
N | A | I | T | P | N | P | V | T | V | P | S | H | H | G | P | D | V | V | S | V | V | P | E | F | E | G | K | I | L | T | S | A | V | I | V | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
| T | T |
| S | S |
|
|
| S | . | . | . | . | . | . | . | S |
|
|  |  | S | S | S | S | S | S |
| T |  |  |  |  |  |  |  |  |
| G | G | G | T | T | S |  |  |  |  |  |  |  |  | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
149 | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . |
  |
  |   |
235 | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |
|
|  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | K | T | G | S | V | T | E | L | V | S | I | L | G | K | K | V | T | A | E | E | V | N | N | A | L | K | Q | A | T | T | N | . |
. |
. |
. |
. |
. |
N | E | S | F | G | Y | T | D | E | E | I | V | S | S | D | I | I | G | S | H | F | G | S | V | F | D | A | T | Q | T | E | I | T | A | V | G | D | L | Q | L | V | K |
Query Conservation |   |
|   |   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |
|   |
|
|
|   |   |   |
|
|   |
|   |   |   | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|
|   |   |   |
|   |
|   |
|   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |   |
|   |
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   | . |
|   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | T | L | M | H | M | H | T | L | M | V | E | V | D | G | D | V | S | R | D | D | I | L | E | A | I | K | K | T | P | R | I | I | T | V | R | A | E | D | G | F | S | S | T | A | K | I | I | E | Y | G | R | D | L | . |
G | R | L | R | Y | D | I | N | E | L | V | V | W | E | E | S | I | N | V | L | E | N | E | I | F |
Template Known Secondary structure |   |
|
| S |
|  |  |  |  |  |  |  |  |  |  | S |
|
|
|  |  |  |  |  |  |  |  |  |  | S | T | T |  |  |  |  |
| G | G | G | T |
|
| S |  |  |  |  |  |  |  |  |  |  |  | . | T |
| G | G | G |
|
|
| S |  |  |  |  | G | G | G |
|  |  |  | T | T |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
222 | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | |
. | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 |
  |
  |   |
309 | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | V | A | W | Y | D | N | E | Y | G | F | V | T | Q | L | I | R | T | L | E | K | F | A | K | L |
Query Conservation |   |
  |   |   |
|
|
|
|
|   |
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|
|   |   |
|   |
|
|   |
|
|   |   |
|
|   |   |   |   |
Template Sequence |   |
L | M | Q | A | V | H | Q | E | S | I | V | I | P | E | N | I | D | C | I | R | A | M | L | Q | M |
Template Known Secondary structure |   |
 |  |  |  |  |
| T | T | T | T | T |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
301 | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . |
  |