|   |
22 | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | D | F | L | L | T | W | E | Q | T | P | D | E | L | K | Q | V | L | D | V | A | A | A | L | K | A | L | R | A | E | N | I | S | T | K | V | F | N | S | G | L | G | I | S | V | F | R | D | N | S | T | R | T | R | F | S | Y | A | S | A | L | N | L | L | G | L | A | Q | Q | D | L | D | E | G | K | S | Q | I | A | H |
Query Conservation |   |
|
|
|
|   |   |   |
|   |
|   |   |
|
|   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |
|
|   |
|
|
|
|
|
|
|   |
|
|
|   |
|   |   |   |
|
|
|   |   |
|   |
|   |   |   |   |
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |
|   |
|
|   |   |   |
|
|   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |   | . | . | . | . | . | . |
|   |   |
|   |   |   |
|   |
|   |   |
|
|
|
|
|
|   |
|
|
|   |
|   |   |   |
|
|
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |
Template Sequence |   |
R | S | L | I | S | S | L | D | L | T | R | E | E | V | E | E | I | L | K | Y | A | K | E | F | K | E | G | K | E | E | . |
. |
. |
. |
. |
. |
T | I | K | A | S | A | V | L | F | F | S | E | P | S | T | R | T | R | L | S | F | E | K | A | A | R | E | L | G | I | E | T | Y | L | V | S | G | S | E | S | S | T | V | K |
Template Known Secondary structure |   |
|
| B |
|
| G | G | G |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  | T | T | T | T | S |
|
| T |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . |
  |
  |   |
102 | . | . | . | . | . | . | . | 110 | . | . | . | . | . | |
. | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | E | T | V | R | E | T | A | N | M | I | S | F | C | . |
A | D | A | I | G | I | R | D | D | M | Y | L | G | A | G | N | A | Y | M | R | E | V | G | A | A | L | D | D | G | Y | K | Q | G | V | L | P | Q | R | P | A | L | V | N | L | Q | C | D | I | D | H | P | T | Q | S | M | A | D | L | A | W | L | R | E | H | F |
Query Conservation |   |
|
|
|
|   |
|
|
|
|
|
|
|   |
| . |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|
|
|
|
|   |   |
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |
|
|
|   |
|
|
|   |   |   |   |
|   |
|
|   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |
|   |   |
|   |
|
|
|
|
|
|   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |   |
Template Sequence |   |
G | E | S | F | F | D | T | L | K | T | F | E | G | L | G | F | D | Y | V | V | F | R | V | P | F | V | F | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | Y | K | E | I | V | K | S | L | N | L | R | L | V | N | A | G | D | G | T | H | Q | H | P | S | Q | G | L | I | D | F | F | T | I | K | E | H | F |
Template Known Secondary structure |   |
T |
|
|  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |  | S | S |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | S |
|  |  |  |  |  | T |
| S | S |  |  |  |  |  |  |  | T | T | T | B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
76 | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . |
  |
  |   |
181 | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | S | L | E | N | L | K | G | K | K | I | A | M | T | W | A | Y | S | P | S | Y | G | K | P | L | S | V | P | Q | G | I | I | G | L | M | T | R | F | G | M | D | V | T | L | A | H | P | E | G | Y | D | L | I | P | D | V | V | E | V | A | K | N | N | A | K | A | S | G | G | S | F | R | Q | V | T | S | M | E | E | A |
Query Conservation |   |
|   |   |   |   |
|   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|
|   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |
|   |   |
|
|
Alig confidence |   |
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
| . | . | . |   |
|   |
|   |
|
|
|   |
|
|
| . | . | . | . | . |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|
Template Sequence |   |
G | . |
. |
. |
E | V | K | D | L | R | V | L | Y | V | G | D | . |
. |
. |
. |
. |
I | K | H | S | R | V | F | R | S | G | A | P | L | L | N | M | F | G | A | K | I | G | V | C | G | P | K | T | L | I | P | R | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | E | V | F | K | V | D | V | F | D | D | V | D | K | G |
Template Known Secondary structure |   |
S | . | . | . |
|
| T | T |
|  |  |  |  |  | S |
| . | . | . | . | . |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  | S |
| G | G | G | S |
| T | T | . | . | . | . | . | . | . | . | . | . | . | G | G | G | G |
|  |  |  |  | S | S |  |  |  |  |
Template Predicted Secondary structure |   |
| . | . | . |
|
|
|
|
|  |  |  |  |  |
|
| . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
142 | |
|
|
. | . | . | . | . | . | . | 150 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . |
  |
  |   |
261 | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | K | D | A | D | I | V | Y | P | K | S | W | A | P | Y | K | V | M | E | E | R | T | E | L | L | R | A | N | D | H | E | G | L | K | A | L | E | K | Q | C | L | A | Q | N | A | Q | H | K | D | W | H | C | T | E | E | M | M | E | L | T | R | D | G | E | A | L | Y | M | H | C | L | P | A | D | I | S | G | V | S | C |
Query Conservation |   |
|   |   |
|
|
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|
|   |   |
|   |   |   |
|
|
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
  |   |   |
|
|
|
|
| . | . | . |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|   |   | . | . | . | . | . | . |
Template Sequence |   |
I | D | W | A | D | V | V | I | . |
. |
. |
W | L | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | Q | K | E | R | Q | K | E | N | Y | I | P | S | E | S | S | Y | F | K | Q | F | G | L | T | K | E | R | F | E | K | V | K | L | Y | M | H | P | G | P | V | N | . |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |
| S |  |  |  | . | . | . |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
| T |  |  |  |  | T | T | S | S | S |
|  |  |  |  |  |  |  |  | S | B |
|  |  |  |  | T | T |
|
|
|  |  |
| S | S |
|
|
| . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  | . | . | . |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
| . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
203 | . | . | . | . | . | . | 210 | |
|
|
. | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | |
|
|
|
|
|
  |
  |   |
341 | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | E | G | E | V | T | E | G | V | F | E | K | Y | R | I | A | T | Y | K | E | A | S | W | K | P | Y | I | I | A | A | M | I | L | S |
Query Conservation |   |
|   |   |
|
|
|   |
|
|   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|
|   |   |   |   |
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|   |   |   |
|   |   |   |
|   |
|   |
|   |   |
|
|   |
|
|
|   |   |   |   |
|
|
|   |   |
Template Sequence |   |
R | N | V | D | I | D | H | E | L | V | Y | T | E | K | S | L | I | Q | E | Q | V | K | N | G | I | P | V | R | K | A | I | Y | K | F |
Template Known Secondary structure |   |
B | T | T | T | B |
| G | G | G | S | S | S | T | T | B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
255 | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . |
  |