|   |
823 | . | . | . | . | . | . | 830 | . | . | . | . | . | . | |
. | . | . | 840 | . | . | . | . | . | . | . | . | . | |
850 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 860 | . | . | . | . | . | . | . | . | . | 870 | . | . | . | . | . | . | . | . | . | 880 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|  |  |  | . |
|
|
|
|
|
|
|
|  |  |  |
|
| . |
|  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | E | R | P | A | T | T | L | R | D | L | L | A | I | . |
T | P | G | E | N | A | V | N | I | A | D | V | E | . |
P | A | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | L | F | K | R | F | D | T | A | A | M | S | I | G | A | L | S | P | E | A | H | E | A | L | A | E | A | M | N | S | I | G | G | N | S | N |
Query Conservation |   |
  |   |   |   |   |   |   |
|
|   |
|
|
|
| . |   |   |   |   |   |
|
|
|
|
|
|
|
| . |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |
|
|
|   |
|
|   |
|
|   |
|
|
|
|   |   |
|   |   |
|
|
|   |
|   |   |   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |
|   |
|
|
|   | . | . | . | . | . |   |   |
|
|   |
|   |
|   |   |
|
|
|
|   |
Template Sequence |   |
Y | N | E | P | C | H | T | F | N | E | Y | L | L | I | P | G | L | S | T | V | D | C | I | P | S | N | V | N | L | S | T | P | L | V | K | F | Q | K | G | Q | Q | S | E | I | N | L | K | I | P | L | V | S | A | I | M | Q | S | V | S | G | . |
. |
. |
. |
. |
E | K | M | A | I | A | L | A | R | E | G | G | I | S | F |
Template Known Secondary structure |   |
| S | S |
|
|
|
| G | G | G |  |  |  |
|
|
|
|
|
| T | T |
|
| G | G | G |
| B |
|
|  |  |
| S |
|  |  | T | T | S |
|
| S |
|  |  | S | S | S |  |  |  |
| S |
| T | T | T |
| S | . | . | . | . | . |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . |
  |
  |   |
889 | 890 | . | . | . | . | . | . | . | . | . | 900 | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | . | . | . | 920 | . | . | . | . | . | . | . | . | . | 930 | . | . | . | . | . | . | . | . | . | 940 | . | . | . | . | . | . | . | . | . | 950 | . | . | . | . | . | . | . | . | . | 960 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | G | E | G | G | E | D | P | A | R | Y | G | T | N | K | V | S | R | I | K | Q | V | A | S | G | R | F | G | V | T | P | A | Y | L | V | N | A | D | V | I | Q | I | K | V | A | Q | G | A | K | P | G | E | G | G | Q | L | P | G | D | K | V | T | P | Y | I | A | K | L | R | Y | S | V | P | G | V | T | L | I | S | P |
Query Conservation |   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|   |   |   |   |
|   |   |
|   |   |
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |   |
|
|   |   |
|   |   |   |
|
|
|   |
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |
|   |
|   |   |
Template Sequence |   |
I | F | G | S | Q | S | I | E | S | Q | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | M | V | H | A | V | K | N | F | R | Y | L | V | G | A | G | I | N | T | R | D | F | R | E | R | V | P | A | L | V | E | A | G | A | D | V | L | C | I | D | S |
Template Known Secondary structure |   |
 |
|
| S | S |
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  | T |
|
|
|
|
|  |  |  |  |
| S | S | S |  |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . |
  |
  |   |
969 | 970 | . | . | . | . | . | . | . | . | . | 980 | . | . | . | . | . | . | . | . | . | 990 | . | . | . | . | . | . | . | . | . | 1000 | . | . | . | . | . | . | . | . | . | 1010 | . | . | . | . | . | . | . | . | . | 1020 | . | . | . | . | . | . | . | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | P | H | H | D | I | Y | S | I | E | D | L | A | Q | L | I | F | D | L | K | Q | V | N | P | K | A | M | I | S | V | K | L | V | S | E | P | G | V | G | T | I | A | T | G | V | A | K | A | Y | A | D | L | I | T | I | A | G | Y | D | G | G | T | G | A | S | P | L | S | S | V | K | Y | A | G | C | P | W | E | L | G |
Query Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|   |   |
|   |   |
|   |
|   |
|
|
|
|   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|   |
|
|   |
|   |
|
|
|   |
|
|
|
|
|
|
|   |   |   |
|   |
|   |   |
|   |
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   | . | . | . |   |
|
|
|
|
|
|   |
|   | . | . | . |
|   |
|   |
|   |   |
|   |   |
|
|
|
|   |
|   |
|   |
|   |
|
|   |   |   |   |   |   |   |   | . | . |   |   |   |
|   |
|   |   |   |   |
Template Sequence |   |
S | D | G | F | S | E | W | Q | K | I | T | I | G | W | I | R | E | K | Y | G | D | . |
. |
. |
K | V | K | V | G | A | G | N | I | V | . |
. |
. |
D | G | E | G | F | R | Y | L | A | D | A | G | A | D | F | I | K | I | G | I | G | G | G | S | I | C | I | T | R | E | Q | . |
. |
K | G | I | G | R | G | Q | A | T | A |
Template Known Secondary structure |   |
S |
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | . | . | . | G | S |
|  |  |  |  |  |  |
| . | . | . | S |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |
| S | S |
| S | T | T | B |
|  |  |  |  | . | . | T |
|
|
|
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|  |  |  |  |  |
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
263 | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | |
|
|
. | . | . | . | . | . | 290 | . | . | . | |
|
|
. | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | |
|
. | . | . | . | . | 330 | . | . | . | . |
  |
  |   |
1049 | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | |
|
. | . | . | . | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080 | . | . | . | . | . | . | . | . | . | 1090 | . | . | . | . | . | . | . | |
|
|
. | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | 1120 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . |  |  |  |  |  |  |
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | V | E | T | Q | Q | A | L | V | A | N | G | L | R | H | . |
. |
K | I | R | L | Q | V | D | G | G | L | K | T | G | V | D | I | I | K | A | A | I | L | G | A | E | S | F | G | F | G | T | G | P | M | . |
. |
. |
V | A | L | G | C | K | Y | L | R | I | C | H | L | N | N | C | A | T | G | V | A | T | Q | D | D | K |
Query Conservation |   |
|   |
|   |   |   |   |
|   |   |   |
|
|
|   | . | . |   |
|   |
|   |   |
|
|
|   |   |
|   |   |
|
|   |   |
|   |   |
|
|
|   |   |   |   |   |
|
|   |   |
| . | . | . |
|
|   |
|
|
|
|   |
|   |
|
|   |   |   |
|
|
|
|
|
|
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|
|
|   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |
|
|   |
|   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|   |   |
|   |
Template Sequence |   |
V | I | D | V | V | A | E | R | N | K | Y | F | E | E | T | G | I | Y | I | P | V | C | S | D | G | G | I | V | Y | D | Y | H | M | T | L | A | L | A | M | G | A | D | F | I | M | L | G | R | Y | F | A | R | F | E | E | S | P | T | R | K | V | T | I | N | G | S | V | M | K | E | Y | W | G | E | G | S | S | R | A | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |  |  |
|
|  |  |  |  | S |
|
|
| S |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  | S |  |  |  |  | T | B | T | T | S | S | S |
|  |  |  |  | T | T |  |  |  |  |  |  |  |
| T | T | S | T | T | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |
|
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
335 | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . |
  |
  |   |
1124 | . | . | . | . | . | 1130 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 1140 | . | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | R | K | N | H | Y | H | G | L | P | F | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | T | N | Y | F | E | F | I | A | R | E | T | R | E | L | M | A | Q | L | G | V | T | R | L | V | D | L | I | G | R | T | D | L | L | K | E | L |
Query Conservation |   |
|   |   |   |   |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |
|
|   |   |
|   |   |
|   |
|
|
|   |
|
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |
|
|   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
N | W | Q | R | Y | D | L | G | G | K | Q | K | L | S | F | E | E | G | V | D | S | Y | V | P | Y | A | G | K | L | K | D | N | V | E | A | S | L | N | K | V | K | S | T | M | C | N | C | G | A | L | T | I | P | Q | L | Q | S | K | A | K | I | T | L | V | S |
Template Known Secondary structure |   |
| G | G | G | G |
| S | S | S |
| S | S |
| S | S |
|
| B |
|  |  |  |  |  |
|
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S | B |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
415 | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . |
  |