Job Description P31552 Confidence 100.00% Date Thu Jan 5 11:48:13 GMT 2012 Rank 7 Aligned Residues 508 % Identity 22% Template c3eynB_ PDB info PDB header:ligase Chain: B: PDB Molecule:acyl-coenzyme a synthetase acsm2a; PDBTitle: crystal structure of human acyl-coa synthetase medium-chain2 family member 2a (l64p mutation) in a complex with coa Resolution 1.90 Å

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		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.		.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																									.
Query SS confidence																																																									.
Query Sequence		M	D	I	I	G	G	Q	H	L	R	Q	M	W	D	D	L	A	D	V	Y	G	H	K	T	A	L	I	C	E	S	S	G	G	V	V	N	R	Y	S	Y	L	E	L	N	Q	E	I	N	R	T	A	N	L	F	Y	.	T	L	G	I	R	K	G	D	K	V	A	L	H	L	D	N	C	P	E	F	I	F	C	W
Query Conservation																																																									.
Alig confidence																																																									.
Template Conservation
Template Sequence		F	N	F	A	S	D	V	L	D	H	W	A	D	M	E	K	A	G	K	R	P	P	S	P	A	L	W	W	V	N	G	K	G	K	E	L	M	W	N	F	R	E	L	S	E	N	S	Q	Q	A	A	N	V	L	S	G	A	C	G	L	Q	R	G	D	R	V	A	V	V	L	P	R	V	P	E	W	W	L	V	I
Template Known Secondary structure								T										T	T	S	S											S	S	S																							T	T	T				T	T									S
Template Predicted Secondary structure
Template SS confidence
		44	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.
		80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	G	L	A	K	I	G	A	I	M	V	P	I	N	A	R	L	L	C	E	E	S	A	W	I	L	Q	N	S	Q	A	C	L	L	V	T	S	A	Q	F	Y	P	M	Y	Q	Q	I	Q	Q	E	D	A	T	Q	L	R	H	I	C	L	T	D	V	A	L	P	A	D	D	G	V	S	S	F	T	Q	L	K	N	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	G	C	I	R	A	G	L	I	F	M	P	G	T	I	Q	M	K	S	T	D	I	L	Y	R	L	Q	M	S	K	A	K	A	I	V	A	G	D	E	V	I	Q	E	V	D	T	V	A	S	E	C	P	S	L	R	I	K	L	L	V	S	E	K	S	C	D	G	W	L	N	F	K	K	L	L	N	E	A	S	T
Template Known Secondary structure							T	T								T	T														T		S						T	T	T								G	G	G		T	T								S	S	S			T	T											S		S
Template Predicted Secondary structure
Template SS confidence
		124	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.
		160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	P	A	T	L	C	Y	A	P	P	L	S	T	D	D	T	A	E	I	L	F	T	S	G	T	T	S	R	P	K	G	V	V	I	T	H	Y	N	L	R	F	A	G	Y	Y	S	A	W	Q	C	A	L	R	D	D	D	V	Y	L	T	V	M	P	A	F	H	I	D	C	Q	C	T	A	A	M	A	A	F	S	A
Query Conservation
Alig confidence										.	.	.	.	.	.	.
Template Conservation										.	.	.	.	.	.	.
Template Sequence		T	H	H	C	V	E	T	G	.	.	.	.	.	.	.	S	Q	E	A	S	A	I	Y	F	T	S	G	L	P	K	M	A	E	H	S	Y	S	S	L	G	L	K	A	K	M	D	A	G	W	T	G	L	Q	A	S	D	I	M	W	T	I	S	D	T	G	W	I	L	N	I	L	C	S	L	M	E	P	W	A	L
Template Known Secondary structure									B	.	.	.	.	.	.	.	T	T	S																													T	T	T	T	S			T	T									T	T	S							T	T
Template Predicted Secondary structure										.	.	.	.	.	.	.
Template SS confidence
		204	.	.	.	.	.	210	.								.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.
				240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.
Predicted Secondary structure		.	.
Query SS confidence		.	.
Query Sequence		.	.	G	A	T	F	V	L	V	E	K	Y	S	A	R	A	F	W	G	Q	V	Q	K	Y	R	A	T	V	T	E	C	I	P	M	M	I	R	T	L	M	V	Q	P	P	S	A	N	D	Q	Q	H	R	L	R	E	V	M	F	Y	L	N	L	S	E	Q	E	K	D	A	F	C	E	R	F	G	V	R	L	L	T
Query Conservation		.	.
Alig confidence		.	.
Template Conservation
Template Sequence		G	A	C	T	F	V	H	L	L	P	K	F	D	P	L	V	I	L	K	T	L	S	S	Y	P	I	K	S	M	M	G	A	P	I	V	Y	R	M	L	L	Q	Q	D	L	S	S	Y	K	F	P	H	L	Q	N	C	V	T	V	G	E	S	L	L	P	E	T	L	E	N	W	R	A	Q	T	G	L	D	I	R	E
Template Known Secondary structure		T									S	S													S																	T	S		T	T	S	S			T	T								S	S															S
Template Predicted Secondary structure
Template SS confidence
		280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.
		318	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.			.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.
Predicted Secondary structure																																																											.	.
Query SS confidence																																																											.	.
Query Sequence		S	Y	G	M	T	E	T	I	V	G	I	I	G	D	R	P	G	D	K	R	R	W	P	S	I	G	R	V	G	F	C	Y	E	A	E	I	R	D	D	H	N	R	P	L	P	A	G	E	I	G	E	I	C	I	K	G	I	.	.	P	G	K	T	I	F	K	E	Y	F	L	N	P	Q	A	T	A	K	V	L	E
Query Conservation																																																											.	.
Alig confidence																			.																																								.	.
Template Conservation																			.
Template Sequence		S	Y	G	Q	T	E	T	G	L	T	C	M	V	S	K	T	M	.	K	I	K	P	G	Y	M	G	T	A	A	S	C	Y	D	V	Q	I	I	D	D	K	G	N	V	L	P	P	G	T	E	G	D	I	G	I	R	V	K	P	I	R	P	I	G	I	F	S	G	Y	V	D	N	P	D	K	T	A	A	N	I	R
Template Known Secondary structure						T	T	T								T	T	S	.				T	T							T	T								T	T	S		B			T	T										S	S	B			T	T	S					T	T								T
Template Predicted Secondary structure																			.
Template SS confidence
		360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.		.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.
		396	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	D	G	W	L	H	T	G	D	T	G	Y	R	D	E	E	D	F	F	Y	F	V	D	R	R	C	N	M	I	K	R	G	G	E	N	V	S	C	V	E	L	E	N	I	I	A	A	H	P	K	I	Q	D	I	V	V	V	G	I	K	D	S	I	R	D	E	A	I	K	A	F	V	V	L	N	E	G	E	T	L
Query Conservation
Alig confidence		.
Template Conservation		.
Template Sequence		.	G	D	F	W	L	L	G	D	R	G	I	K	D	E	D	G	Y	F	Q	F	M	G	R	A	D	D	I	I	N	S	S	G	Y	R	I	G	P	S	E	V	E	N	A	L	M	E	H	P	A	V	V	E	T	A	V	I	S	S	P	D	P	V	R	G	E	V	V	K	A	F	V	V	L	A	S	Q	F	L	S
Template Known Secondary structure		.	T	T												T	T	S								G	G	G					T	T														T	S	T	T												T	T	T												G	G	G	G	G
Template Predicted Secondary structure		.
Template SS confidence
			439	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.
		476						.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.
Predicted Secondary structure			.	.	.	.	.
Query SS confidence			.	.	.	.	.
Query Sequence		S	.	.	.	.	.	E	E	E	F	F	R	F	C	E	Q	N	M	A	K	F	K	V	P	S	Y	L	E	I	R	K	D	L	P	R	N	C	S	G	K	I	I	R	K	N	L	K
Query Conservation			.	.	.	.	.
Alig confidence			.	.	.	.	.
Template Conservation
Template Sequence		H	D	P	E	Q	L	T	K	E	L	Q	Q	H	V	K	S	V	T	A	P	Y	K	Y	P	R	K	I	E	F	V	L	N	L	P	K	T	V	T	G	K	I	Q	R	A	K	L	R
Template Known Secondary structure		S																	S		G	G	G	S		S						S				B		T	T			B
Template Predicted Secondary structure
Template SS confidence
		518	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.