|   |
8 | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | |
|
|
30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | |
|
|
. | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | |
|
|
. | . |
Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
| . | . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
Query Sequence |   |
G | E | H | F | F | T | T | S | D | N | T | A | L | F | Y | R | H | W | P | A | L | Q | . |
. |
. |
P | G | A | K | K | V | I | V | L | F | H | R | G | H | E | H | S | G | R | . |
. |
. |
L | Q | H | L | V | D | E | L | A | M | P | D | T | A | F | Y | A | W | D | A | R | G | H | G | K | S | S | G | . |
. |
. |
P | R |
Query Conservation |   |
  |
|   |   |
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |
|   |   |
|
|
|   |
|
|   |   |
|   |   |   |   | . | . | . |
|   |   |
|
|   |   |
|
|   |   |
|
|   |
|   |   |   |
|   |
|
|
|
|   |
|   |
| . | . | . |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
Template Conservation |   |
|   |
|   |   |   |
|   |
|
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | Q | I | F | Y | P | S | K | D | G | T | K | I | P | M | F | I | V | H | K | K | G | I | K | L | D | G | S | H | P | A | F | L | Y | G | Y | G | G | F | N | I | S | I | T | P | N | Y | S | V | S | R | L | I | F | V | R | H | M | G | G | V | L | A | V | A | N | I | R | G | G | G | E | Y | G | E | T | W | H | K | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  | T | T |
|
|
| S | S |
| S |
|  |  |  |  |
|
|
|
| T | T |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
| T | T | S | S | T | T |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
438 | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . |
  |
  |   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | Y | S | P | S | L | A | R | S | V | R | D | V | D | E | F | V | R | F | A | A | S | D | S | Q | V | G | L | E | E | V | V | V | I | A | Q | S | V | G | A | V | L | V | A | T | W | I | H | D | Y | A | P | A | I | R | G | L | V | L | A | S | P | A | F | K | V | K | L | Y | V | P | L | A | R | P | A | L | A | L | W |
Query Conservation |   |
|   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|   |
|
|
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
G | I | L | A | N | K | Q | N | C | F | D | D | F | Q | C | A | A | E | Y | L | I | K | E | G | Y | T | S | P | K | R | L | T | I | N | G | G | S | N | G | G | L | L | V | A | T | C | A | N | Q | R | P | D | L | F | G | C | V | I | A | Q | V | G | V | M | D | M | L | K | F | H | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
T | S | G | G | G | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
| G | G | G |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G |
| S |  |  |  |  |  | S |
|
|
|
| T | T | T | G | G | G | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
| . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
518 | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
  |
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | R | L | R | G | L | F | F | I | N | S | Y | V | K | G | R | Y | L | T | H | D | R | Q | R | G | A | S | F | N | N | D | P | L | I | T | R | A | I | A | V | N | I | L | L | D | L | Y | K | T | S | E | R | I | I | R | D | A | A | A | I | T | L | P | T | Q | L | L | I | S | G | D | D | Y | V | V | H | R | Q | P | Q |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |   |   |
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |
|   |   |
|   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
Y | T | I | G | H | A | W | T | T | D | Y | G | S | D | S | K | Q | H | F | E | W | L | I | K | Y | S | P | L | H | N | V | K | L | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | A | D | D | I | Q | Y | P | S | M | L | L | L | T | A | D | H | D | D | R | V | V | P | L | H | S |
Template Known Secondary structure |   |
. | . | . | . | . | . | S | T | T | G | G | G | G |  |  |  |  |
|
|
| S |  |  |  |  |  |  |  |  |  |  |
| G | G | G |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | S | S | T | T |
|
|
|
|  |  |  |  |  |  |  | T | T |
|
| S | S |
| T |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
589 | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . |
  |
  |   |
239 | 240 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | |
. | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | D | F | Y | Q | R | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
R | S | P | L | K | E | L | H | L | L | P | G | F | Y | H | D | T | L | G | E | E | N | . |
R | A | L | A | F | E | K | M | Q | S | F | I | S | R | L | Y |
Query Conservation |   |
  |   |   |
|
|   |
| . | . | . | . | . | . | . | . | . |   |
|   |   |
|
|
|   |   |
|   |
|   |   |
|   |
|
|   |
|   |   | . |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
Template Sequence |   |
L | K | F | I | A | T | L | Q | Y | I | V | G | R | S | R | K | Q | N | N | P | L | L | I | H | V | D | T | K | A | G | H | G | A | G | K | P | T | A | K | V | I | E | E | V | S | D | M | F | A | F | I | A | R | C | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T | T | S | T | T |
|
| S |
|  |  |  |  |  |  | S | S |
|
| S | S | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . |
  |