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Job DescriptionP76092
Confidence99.78%DateThu Jan 5 12:18:46 GMT 2012
Rank244Aligned Residues243
% Identity11%Templatec2px6A_
PDB info PDB header:transferaseChain: A: PDB Molecule:thioesterase domain; PDBTitle: crystal structure of the thioesterase domain of human fatty2 acid synthase inhibited by orlistat
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  FTTSDNTALFYRHWPALQPGAKKVIVLFHRGHEHSGRLQHLVDELAMPDTAFYAWDARGHGKSSGPRGYSPSLARSVRDV
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Template Sequence  LVNPEGPTLMRLNSVQSSERP. . . LFLVHPIEGSTTVFHSLASRL. . . SIPTYGLQCTRAAPL. . . . . . . DSIHSLAAYY
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   2223......2230.........2240... ......2250.........2260.... .....2270......... 2280.........
 
   92.......100.........110.........120........ .130.........140.........150.........160........
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Query Sequence  DEFVRFAASDSQVGLEEVVVIAQSVGAVLVATWIHDY. . . APAIRGLVLASPAFKVKLYVPLARPALALWHRLRGLFFIN
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Template Sequence  IDCIRQVQ. . . . . PEGPYRVAGYSYGACVAFEMCSQLQAQQPTHNSLFLFDGSPTYAEAETEAICFFVQQFTDMEHNRVL
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   2290....... ..2300.........2310.........2320.........2330.........2340.........2350.........2360....
 
   169170.........180.........190.........200.........210...... ...220.........230.........240...
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Query Sequence  SYVKGRYLTHDRQRGASFNNDPLITRAIAVNILLDLYKTSERIIRDAA. . . . . AITLPTQLLISGDDYVVHRQPQIDFYQ
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Template Sequence  EALLPLKGLEERVAAAVDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGADYNLS. . . . . . .
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   2385....2390.........2400.........2410.........2420.........2430.........2440.........2450.......
 
   244.....250.........260.........270.........
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Query Sequence  RLRSPLKELHLLPGFYHDTLGEENRALAFEKMQSFI
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Template Sequence  QVCDGKVSVHVIEGDHRTLLEGSGLESIISIIHSSL
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   2466...2470.........2480.........2490.........2500.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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