|   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | S | F | F | H | W | G | I | S | A | W | A | T | Y | T | L | A | S | L | I | M | A | Y | H | F | H | V | R | K | N | K | G | L | S | L | S | G | I | I | A | A | I | T | G | V | R | P | Q | G | P | W | G | K | L | V | D | L | M | F | L | I | A | T | V | G | A | L | T | I | S | L | V | V | T | A | A | T | F | T | R |
Query Conservation |   |
  |
|   |
|
|
|
|   |   |
|
|
|
|
|   |
|   |
|
|
|   |
|
|   |   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |   |
|
|
|
|   |
|   |   |
|   |   |
|   |   |
|
|
|
|   |
|   |
|
|
|   |
|   |
|
|
|
|
|
|
|   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   | . |   |   | . |
|
|   |   |   |   |
|
|   |
|   |
|   |   |
|
|
| . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
Template Sequence |   |
L | A | I | A | S | Y | E | W | M | S | A | I | T | L | I | I | V | G | K | Y | F | L | P | . |
I | F | . |
I | E | K | G | I | Y | T | I | P | E | F | V | E | K | R | F | N | . |
. |
. |
. |
. |
. |
. |
K | K | L | K | T | I | L | A | V | F | W | I | S | L | Y | I | F | V | N | L | T | S | V | L | Y | L | G | G | L |
Template Known Secondary structure |   |
G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |  |  | . |  |  | . |  |  | T | T |
|
| S |  |  |  |  |  |  |  |  | T |
| . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  | . |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | |
. | . | |
. | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . |
  |
  |   |
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | L | S | A | L | T | G | L | P | D | N | F | T | V | Q | A | F | V | I | L | L | S | G | G | I | F | C | L | S | S | W | I | G | I | N | N | G | L | Q | R | L | S | K | M | V | G | W | G | A | F | L | L | P | L | L | V | L | I | V | G | P | T | E | F | I | T | N | S | I | I | N | A | I | G | L | T | T | Q | N | F |
Query Conservation |   |
|
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|
|   |   |
|   |   |   |
|
|   |
|
|
|
|   |
|
|   |   |
|   |   |
|   |   |   |
|
|   |   |
|
|   |   |
|
|
|   |
|
|
|   |   |   |   |   |
|
|
|   |
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|
|   |   | . | . |   |   |   |
|
|
|   |   |   |   |   |   |   |
|
|   | . | . | . |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | L | E | T | I | L | G | I | P | L | . |
. |
M | Y | S | I | L | G | L | A | L | F | A | L | V | Y | S | I | . |
. |
. |
V | V | W | T | D | V | I | Q | V | F | F | L | V | L | G | G | F | M | T | T | Y | M | A | V | S | F | I | G | G | T | D | G | W | . |
F | A | G | V | S | K | M | V | D | A | A | P | G | H | F |
Template Known Secondary structure |   |
 |  |  |  |  | T | T |
|
|  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . | . | . |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  | . |  |  |  |  |  |  |  |  |  |  |
| G | G | G | G |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
153 | . | . | . | . | . | . | 160 | . | . | |
|
. | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | |
|
|
. | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | |
. | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . |
  |
  |   |
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | |
|
|
. | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | Q | M | S | L | F | T | D | P | L | G | D | G | S | F | T | R | N | W | T | V | F | Y | W | L | W | W | I | S | Y | T | P | G | V | . |
. |
. |
A | M | F | V | T | R | V | S | R | G | R | K | I | K | E | V | I | W | G | L | I | L | G | S | T | V | G | C | W | F | F | F | G | V | M | E | S | Y | A | I | H | Q | F |
Query Conservation |   |
  |   |
|
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|   |   |
|
|   |   |   |   |
|
|
|   |
|   |
|
|   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
Template Sequence |   |
E | M | I | L | D | Q | S | N | P | . |
. |
Q | Y | M | N | L | P | G | I | A | V | L | I | G | G | L | W | V | A | N | L | Y | Y | W | G | F | N | Q | Y | I | I | Q | R | T | L | A | A | K | S | V | S | E | A | Q | K | G | I | V | F | A | A | F | L | K | L | I | V | P | F | L | V | V | L | P | G | I | A | A | Y | V |
Template Known Secondary structure |   |
| S | S |
|
| S | S | S | S | . | . | G | G | G | G | S |
| T | T |  |  |  |  | S | T |  |  |  |  |  |  |  |  | T | T | T | T |
|  |  |  |  |  |  |  | S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G | T | T |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
233 | . | . | . | . | . | . | 240 | . | |
|
. | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 |
  |
  |   |
317 | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 380 | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
I | N | G | V | I | N | V | P | Q | V | L | E | T | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | G | E | T | A | V | Q | Q | V | L | M | S | L | P | A | G | K | L | F | L | A | A | Y | L | G | V | M | I | I | F | L | A | S | H | M | D | A | V | A | Y | T | M | A | A | T | S | T | . |
. |
. |
. |
. |
R | N | L | Q | E |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |
|   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |
|
|   |
|   |   |
|
|   |   |
|
| . | . | . | . | . |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
| . | . |   |   |
|   |
|
|   |   |
|   |
|
|
|
|   |
|
|
|   |   |
|   |
|   |   |   |
|
|   |   |   |   |
|
|   |   |   |   |   |   |   |
Template Sequence |   |
I | T | S | D | P | Q | L | M | A | S | L | G | D | I | A | A | T | N | L | P | S | A | A | N | A | D | K | A | Y | P | W | L | T | Q | F | L | P | . |
. |
V | G | V | K | G | V | V | F | A | A | L | A | A | A | I | V | S | S | L | A | S | M | L | N | S | T | A | T | I | F | T | M | D | I | Y | K | E | Y | I | S | P |
Template Known Secondary structure |   |
 |  |  |
|  |  |  |  |  |  |  |
| T | T |
|
| S |
|
|
|
| S | S | S | G | G | G |  |  |  |  |  |  | T | T |
|
| . | . | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|
| S |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
311 | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | |
|
. | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . |
  |
  |   |
383 | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | D | D | P | D | R | G | L | R | L | F | W | C | V | V | I | T | L | I | P | L | S | I | L | F | T | . |
. |
. |
. |
. |
. |
G | A | S | L | E | T | M | K | T | T | V | V | L | T | A | L | P | F | L | V | I | L | L | V | K | V | G |
Query Conservation |   |
  |   |
|
|   |   |   |   |
|   |   |
|   |
|   |
|
|   |
|
|   |   |
|
|   |   | . | . | . | . | . | . |
|
|   |
|   |   |
|
|   |   |   |
|
|   |
|
|
|
|   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|
|   |
Template Sequence |   |
D | S | G | D | H | K | L | V | N | V | G | R | T | A | A | V | V | A | L | I | I | A | C | L | I | A | P | M | L | G | G | I | G | Q | A | F | Q | Y | I | Q | E | Y | T | G | L | V | S | P | G | I | L | A | V | F | L | L | G | L | F |
Template Known Secondary structure |   |
| S |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G | G | G | G |
| S |
|  |  |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
389 | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . |
  |