|   |
531 | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | E | L | H | P | F | C | P | P | E | Q | A | E | G | Y | Q | Q | M | I | A | Q | L | A | D | W | L | . |
. |
. |
. |
. |
V | K | L | T | G | Y | D | A | V | C | M | Q | P | N | S | G | A | Q | G | E | Y | A | G | L | L | A | I | R | H | Y | H | E | S | R | N | E | G | H | R | D | I | C | L | I | P | A | S | A | H |
Query Conservation |   |
  |   |   |
|
|
|
|
|   |
|   |
|
|
|   |
|
|   |
|   |
|   |
|   |   |
| . | . | . | . | . |   |
|
|
|
|
|
|   |
|
|
|
|
|   |
|
|
|   |
|
|   |
|
|
|   |   |
|
|
|
|   |   |
|
|
|   |   |   |
|   |   |
|
|
|
|   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   | . | . | . |   |   |
|   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . |
|
|
|   |
|
|
|   |   |
|   |
|
Template Sequence |   |
S | L | N | H | E | Y | L | P | . |
. |
. |
I | L | G | L | P | E | F | R | A | N | A | S | R | I | A | L | G | D | D | S | P | A | I | A | Q | K | R | V | G | S | V | Q | G | L | G | G | T | G | A | L | R | I | G | A | E | F | L | R | R | W | Y | N | G | N | N | N | . |
T | A | T | P | V | Y | V | S | S | P | T | W |
Template Known Secondary structure |   |
T |
|
|
|
|
|
|
| . | . | . | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S | S | S | S |
| . | T | T | S |
|  |  |  |  | S | S |
|
|
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
| . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|
|  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
65 | . | . | . | . | 70 | . | . | |
|
|
. | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | |
. | 130 | . | . | . | . | . | . | . | . | . | 140 |
  |
  |   |
606 | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | |
|
|
. | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | |
|
|
. | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |
| . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . | . | . |  |
|
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | T | N | P | A | S | A | H | M | A | G | M | Q | V | V | V | V | A | C | . |
. |
. |
D | K | N | G | N | I | D | L | T | D | L | R | A | K | A | E | Q | A | G | D | N | L | S | C | I | M | V | . |
. |
. |
T | Y | P | S | T | H | G | V | Y | E | E | T | I | R | E | V | C | E | V | V | H | Q | F | G | G | Q | V | Y |
Query Conservation |   |
|
|
|
|
|
|
|   |   |   |
|   |   |
|
|   |
|   |   | . | . | . |   |   |
|
|   |
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|
| . | . | . |
|   |
|
|
|   |
|
|
|
|   |   |
|   |
|
|   |
|
|
|
|   |   |
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|
Template Sequence |   |
E | N | H | N | S | V | F | M | D | A | G | F | K | D | I | R | T | Y | R | Y | W | D | A | A | K | R | G | L | D | L | Q | G | L | L | D | D | M | E | K | A | P | E | F | S | I | F | I | L | H | A | C | A | H | N | P | T | G | T | D | P | T | P | D | E | W | K | Q | I | A | A | V | M | K | R | R | C | L | F | P | F |
Template Known Secondary structure |   |
T |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |
|
|  |  | T | T | T | T |  |  |
|  |  |  |  |  |  |  |  |  | T | S |
| T | T |
|  |  |  |  |  | S | S | S |
| T | T | T |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
141 | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 |
  |
  |   |
680 | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | |
|
. | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
| . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
| . | . |
|
|  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | D | G | A | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
M | N | A | Q | V | G | I | T | S | P | G | F | I | G | A | D | V | S | H | L | N | L | H | K | T | F | C | I | P | H | G | G | G | G | P | G | . |
. |
M | G | P | I | G | V | K | A | H | L | A | P | F | V | P | G | H | S | V | V | Q | I | E | G | M | L | T | R |
Query Conservation |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . |   |
|
|
|   |
|
|   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|
| . | . |   |
|   |   |
|
|
|   |   |
|
|
|   |
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |   | . | . | . | . | . | . |   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
F | D | S | A | Y | Q | G | F | A | S | G | S | L | D | K | D | A | W | A | V | R | Y | F | V | S | E | G | F | E | L | F | C | A | Q | S | F | S | K | N | F | . |
. |
. |
. |
. |
. |
G | L | Y | N | E | R | V | G | N | L | S | V | V | G | K | D | E | D | N | V | Q | R | V | L | S | Q | M | E | K | I | V | R | T | T |
Template Known Secondary structure |   |
 |  |  | S |
| T | T | T | T | T | S |
|  |  |  |  | T |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |
| T | T | T | S | . | . | . | . | . | . |
|
| G | G | G |
|  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |
| . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
221 | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | |
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . |
  |
  |   |
749 | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | |
|
|
|
. | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | G | A | V | S | A | A | P | F | G | S | A | S | I | L | P | I | S | W | M | Y | I | R | M | M | G | A | E | G | L | K | K | A | S | Q | V | A | I | L | N | A | N | Y | I | A | S | R | L | Q | D | A | F | P | V | . |
. |
. |
. |
L | Y | T | G | R | D | G | R | V | A | H | E | C | I | L | D | I | R | P | L | K | E |
Query Conservation |   |
  |
|   |
|
|   |   |   |   |
|   |
|   |   |   |
|   |
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |
|
|
|   |
|   |
|
|
|
|
|
|   |   |
|
|   |   |   |   |   |
| . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
W | S | N | P | P | S | Q | G | A | R | I | V | A | T | T | L | T | S | P | Q | L | F | A | E | W | K | D | N | . |
V | K | T | M | A | D | R | V | L | L | M | R | S | E | L | R | S | R | L | E | S | L | G | T | P | G | T | W | N | H | I | T | D | Q | I | G | M | F | S | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
T | S | S |
|
| S |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S | S |
|
| T |  |  |  |  |
|
| S | S |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
295 | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | |
. | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | |
|
|
|
|
|
|
|
|
|
|
  |
  |   |
825 | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840 | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | . | . | . | 860 | . | . | . | . | . | . | . | . | . | 870 | . | . | . | . | . | . | . | . | . | 880 | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | T | G | I | S | E | L | D | I | A | K | R | L | I | D | Y | G | F | H | A | P | T | M | S | F | P | V | A | G | T | L | M | V | E | P | T | E | S | E | S | K | V | E | L | D | R | F | I | D | A | M | L | A | I | R | A | E | I | D |
Query Conservation |   |
  |   |
|
|   |
|   |
|
|
|
|
|
|   |
|   |
|
|
|
|
|
|   |   |   |
|
|   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |   |
|   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
| . |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |   |   | . | . | . | . | . | . |
|
|   | . |
|
|
|   |
| . |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |
Template Sequence |   |
. |
T | G | L | N | P | K | Q | V | E | Y | M | I | K | E | K | H | I | Y | L | M | . |
. |
. |
. |
. |
. |
A | S | G | . |
R | I | N | M | C | . |
G | L | T | T | K | N | L | D | Y | V | A | K | S | I | H | E | A | V | T | K | I | Q |
Template Known Secondary structure |   |
. |
|
|
|
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |
|
| . | . | . | . | . | . | T | T |
| . |  |  |  | G | G | . | G |
|
| T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
Template Predicted Secondary structure |   |
. |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  | . | . | . | . | . | . |
|
|
| . |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
363 | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | |
|
|
|
|
|
. | . | . | |
. | . | . | . | 390 | |
. | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . |
  |