|   |
540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | |
|
|
|
. | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | |
|
|
|
. | . | 590 | . | . | . | |
|
. | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . |
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |
|
|
|
| . | . |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | Q | A | E | G | Y | Q | Q | M | I | A | Q | L | A | D | W | L | V | K | L | T | G | Y | D | . |
. |
. |
. |
A | V | C | M | Q | P | N | S | G | A | Q | G | E | Y | A | G | L | L | A | I | R | H | Y | H | . |
. |
. |
. |
E | S | R | N | E | G | . |
. |
H | R | D | I | C | L | I | P | A | S | A | H | G | T | N | P |
Query Conservation |   |
|   |
|
|
|   |
|
|   |
|   |
|   |
|   |   |
|   |
|
|
|
|
|
| . | . | . | . |   |
|
|
|
|
|   |
|
|
|   |
|
|   |
|
|
|   |   |
|
|
|
|   | . | . | . | . |   |
|
|
|   |   | . | . |   |
|   |   |
|
|
|
|   |
|
|
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |
|
|   |   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |
| . |
|
|   |
|
|
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |
|   |   |
Template Sequence |   |
E | I | A | P | V | F | V | L | L | E | Y | V | T | L | K | K | M | R | E | I | I | G | W | P | G | G | S | G | D | G | I | F | S | P | G | . |
G | A | I | S | N | M | Y | A | M | M | I | A | R | F | K | M | F | P | E | V | K | E | K | G | M | A | A | L | P | R | L | I | A | F | T | S | E | H | S | H | F | S | L | K |
Template Known Secondary structure |   |
T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| G | G | G |
| S |  |  |  |  |  | S | S | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |  |  |  |  |
| G | G | G | S |
|
|  |  |  |  |  |  | T | T | S |
| T |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
208 | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | |
. | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . |
  |
  |   |
610 | . | . | . | . | . | . | . | |
|
|
. | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | |
|
|
. | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | |
. | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
| . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| . |
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | S | A | H | M | A | G | M | . |
. |
. |
Q | V | V | V | V | A | C | D | K | N | G | N | I | D | L | T | D | L | R | A | K | A | E | . |
. |
. |
Q | A | G | D | N | L | S | C | I | M | V | T | Y | P | S | T | H | . |
G | V | Y | E | E | T | I | R | E | V | C | E | V | V | H | Q | F | G | G | Q | V | Y | L | D | G |
Query Conservation |   |
|
|
|   |   |   |
|   | . | . | . |   |
|
|   |
|   |   |   |   |
|
|   |
|
|
|   |   |
|
|   |   |   |   | . | . | . |   |   |   |   |   |
|
|
|
|
|
|
|   |
|
|
|   | . |
|
|
|
|   |   |
|   |
|
|   |
|
|
|
|   |   |
|
|
|
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |
|
|
|
|   |   |   |
|   |   |
|   |   |
|   |   |
|   |
|
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |
|   |
|
|
|   |
|
|   |
|
|
| . |
|   |   |
|
|   |
|   |   |   |   |
|   |   |
|
|
|
|
|
Template Sequence |   |
K | G | A | A | A | L | G | I | G | T | D | S | V | I | L | I | K | C | D | E | R | G | K | M | I | P | S | D | L | E | R | R | I | L | E | A | K | Q | K | G | F | V | P | F | L | V | S | A | T | A | G | T | T | V | Y | G | A | F | D | P | . |
L | L | A | V | A | D | I | C | K | K | Y | K | I | W | M | H | V | D | A |
Template Known Secondary structure |   |
 |  |  |  |  | T | T | S |
| G | G | G |  |  |  |  |
| B |
| T | T | S |
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  | B | S |
| T | T | T |
|
| B |
|
| . |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
287 | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | |
. | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . |
  |
  |   |
683 | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . |
|
|
|  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | N | M | N | A | Q | V | G | I | T | S | P | G | F | I | . |
. |
. |
. |
. |
G | A | D | V | S | H | L | N | L | H | K | T | F | C | I | P | H | G | G | G | G | P | G | M | G | P | I | G | V | K | A | H | L | A | P | F | V | P | G | H | S | V | V | Q | I | E | G | M | L | T | R | Q | G | A | V | S | A | A | P | F |
Query Conservation |   |
|
|   |
|
|
|   |
|
|   |   |
|
|
|   | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|
|   |
|   |   |
|
|
|   |   |
|
|
|   |
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |   |
|   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template Conservation |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|
|
|   |   |   |
|
| . |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . |
Template Sequence |   |
A | W | G | G | G | L | L | M | S | R | K | H | K | W | K | L | S | G | V | E | R | A | N | S | V | T | W | N | P | H | M | . |
M | G | V | P | L | Q | C | S | A | L | L | V | R | E | E | G | L | M | Q | N | C | N | Q | M | H | D | L | S | Y | D | T | G | D | K | A | L | Q | C | G | R | H | V | D | . |
. |
. |
. |
. |
Template Known Secondary structure |   |
T | T | G | G | G | G | G | G |
| T | T | T | G | G | G | G | T | T | G | G | G |
| S |  |  |  |  |
|
|
|
| . |
|
|
| S | S |
|
|  |  |  |  |  | S | S | T | T |  |  |  |  |  |  |
|
|
|
| G | G | G |
|
| G | G | G | S | S |
| S | S |
|
|
|
| . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|  |  | . |  |
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
366 | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | |
. | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
  |
  |   |
758 | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
G | S | A | S | I | L | P | I | S | W | M | Y | I | R | M | M | G | A | E | G | L | K | K | A | S | Q | V | A | I | L | N | A | N | Y | I | A | S | R | L | Q | D | A | F | P | V | L | Y | T | G | R | D | G | R | V | A | H | E | C | I | L | D | I | R | P | L | K | E | E | T | G | I | S | . |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|   |
|   |   |   |
|   |
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |
|
|
|   |
|   |
|
|
|
|
|
|   |   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|   | . | . | . | . | . | . | . | . |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
Template Conservation |   |
. | . | . | . | . |
|
|   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
V | F | K | L | W | L | M | W | R | A | K | G | T | T | G | F | E | A | H | V | D | K | C | L | E | L | A | E | Y | L | Y | N | I | I | K | N | R | E | G | Y | E | M | V | F | D | G | K | P | Q | H | T | N | V | C | F | W | Y | I | P | P | S | L | R | T | L | E | E | R | M | S | R | L | S | K | V |
Template Known Secondary structure |   |
. | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | T | T |  |  |  | S | S | S | S |
|
| S | S | S |
|  |  |  |  |  |
|
| T | T | T | T | T |
|
|
|
|  |  |  |  | T | T |  |
Template Predicted Secondary structure |   |
. | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
452 | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . |
  |
  |   |
830 | . | . | . | . | . | . | . | . | . | 840 | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | |
|
|
. | . | . | . | . | 860 | |
. | . | . | . | . | . | . | . | . | 870 | . | . | . | . | . | . | . | . | . | 880 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |  |  |  |  |  |
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | L | D | I | A | K | R | L | I | D | Y | G | F | H | A | P | T | M | S | F | P | V | A | G | T | . |
. |
. |
L | M | V | E | P | T | . |
E | S | E | S | K | V | E | L | D | R | F | I | D | A | M | L | A | I | R | A | E |
Query Conservation |   |
|   |
|
|
|
|
|
|   |
|   |
|
|
|
|
|
|   |   |   |
|
|   |   |   | . | . | . |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|
|   |   |
|
|
|   |
|
|   |   |
|   |   |
|
|   |
|
Template Sequence |   |
A | P | V | I | K | A | R | M | M | E | Y | G | T | T | M | V | S | . |
Y | Q | P | L | G | D | K | V | N | F | F | R | M | V | I | S | N | P | A | A | T | H | Q | D | I | D | F | L | I | E | E | I | E | R | L | G | Q | D |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T | S |
|  |  |  | . |  |  |  |  | T | T |  |  |  |  |  |  |  |
|
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | |
. | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . |
  |