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Job DescriptionP75906
Confidence63.27%DateThu Jan 5 12:15:53 GMT 2012
Rank246Aligned Residues195
% Identity21%Templatec1o7dA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:lysosomal alpha-mannosidase; PDBTitle: the structure of the bovine lysosomal a-mannosidase2 suggests a novel mechanism for low ph activation
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   112... ....120.........130.........140.........150.........160.........170.........
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Query Sequence  TFDD. . . . . . . . . . . . GYQSFYTRVFPILQAFQWPAVWAPVGSWVDTPADKQVKFGDELVDREYFATWQQVREVARSRLV
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Template Sequence  TVDQYFYGIYNNIQPAGVQYILDSVISSLLANPTRRFIYVEIAFFSRWWRQQTN. . . . . . . . . . . ATQKIVRELVRQGRL
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   80.........90.........100.........110.........120.........130... ......140........
 
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Query Sequence  ELASHTWNSHYGIQANATGSLLPVYVNRAYFTDHARYETAAEYRERIRLDAVKMTEYLRTKVEV. . NPHVFVWPYG. EAN
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Template Sequence  EFANGGWVMNDEATTH. . . . . . . . . . . . . . . . . . . . . . . . . . . YGAIIDQMTLGLRFLEETFGSDGRPRVAWHIDPFGHS
Template Known Secondary structure  SS
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   149150.........160.... .....170.........180.........190.........200.
 
   257..260.........270..... ....280.. .......290.......
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Query Sequence  GIAIEELKKLGYDMFFTLE. . . . . . . . . . . . . . . . . . . SGLANAS. QLDSIPRVLIANNPS. . . . . . . . . . . . . . . . . . .
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Template Sequence  REQASLFAQMGFDGFFFGRLDYQDKKVRKKTLQMEQVWRASTSLKPPTADLFTSVLPNMYNPPEGLCWDMLCADKPVVED
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   202.......210.........220.........230.........240.........250.........260.........270.........280.
 
   298.300.........310...... ...320.........330.........340.....
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Query Sequence  . . . . . . . . . . . LKEFAQQIITVQEKSPQRI. . MHIDLDYVYDENLQQMDRNIDVLIQRVKD
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Template Sequence  TRSPEYNAKELVRYFLKLATDQGKLYRTKHTVMTMGSDFQYE. NANTWFKNLDKLIQLVNA
Template Known Secondary structure  TTSTT

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   282.......290.........300.........310.........320... ......330.........340.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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