|   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | T | K | Q | M | L | N | N | A | Q | R | G | G | Y | A | V | P | A | F | N | I | H | N | L | E | T | M | Q | V | V | V | E | T | A | A | N | L | H | A | P | V | I | I | A | G | T | P | G | T | F | T | H | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | T | E | N | L | L | A | L | V | S | A | M | A | K | Q | Y | H | H |
Query Conservation |   |
  |   |
|   |
|
|   |   |
|   |   |   |   |
|
|
|   |
|
|
|   |   |
|   |
|   |   |   |
|
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |
| . | . | . | . |
|
|   |
|
|   |   |
|
|   |   |   |
|   |
|   |
|
|   |
|
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
S | P | G | Q | A | F | R | A | A | L | A | K | E | N | P | L | Q | I | V | G | A | I | N | A | N | H | A | L | L | A | Q | R | A | . |
. |
. |
. |
G | Y | Q | A | I | Y | L | S | G | G | G | V | A | A | G | S | L | G | L | P | D | L | G | I | S | T | L | D | D | V | L | T | D | I | R | R | I | T | D | V | C | P | L |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  | S | S | S |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  | . | . | . | . | T |
| S |  |  |  |  |
|  |  |  |  |  |  | T | T | S |
|
|
| S | S | S |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | |
|
|
|
. | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
  |
  |   |
76 | . | . | . | 80 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | |
|
. | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | |
|
. | 140 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  | . | . |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
Query Sequence |   |
P | L | A | I | H | L | D | H | H | T | K | . |
. |
. |
. |
. |
. |
F | D | D | I | A | Q | K | V | R | S | G | V | R | S | V | M | I | D | A | S | H | L | . |
. |
P | F | A | Q | N | I | S | R | V | K | E | V | V | D | F | C | H | R | F | D | V | S | V | E | A | E | L | G | Q | L | . |
. |
G | G | Q | E | D | D | V |
Query Conservation |   |
|
|   |
|
|
|
|
|   |   |   | . | . | . | . | . | . |   |
|   |
|   |   |
|
|   |   |
|
|
|
|
|
|
|
|
|
|   |
| . | . |
|   |
|
|
|
|   |   |
|   |
|
|
|   |   |
|
|   |   |
|
|   |
|
|
|
|
|
|   |
| . | . |   |
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|   |
|   |
|
|
|   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|   |   |   |   |
|   |   |
|
|
|
Template Sequence |   |
P | L | L | V | D | A | D | I | G | F | G | S | S | A | F | N | V | A | R | T | V | K | S | I | A | K | A | G | A | A | A | L | H | I | E | D | Q | V | A | I | V | S | K | E | E | M | V | D | R | I | R | A | A | V | D | A | R | T | D | P | N | F | V | I | M | A | R | T | D | A | L | A | V | E | G | L | E | A | A | L |
Template Known Secondary structure |   |
|  |  |  |  |
| T | T |
| S | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |
| B |
|
| B |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | T | T | S |  |  |  |  |  |  |
|  |  |  |  |  |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
  |
  |   |
146 | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | |
|
. | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  | . | . |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | V | N | E | A | D | A | L | Y | T | N | P | A | Q | A | R | E | F | A | E | A | T | G | I | D | S | L | A | V | A | I | G | T | A | H | G | M | Y | A | S | A | P | A | L | D | F | S | R | L | E | N | I | R | Q | W | V | N | L | P | L | . |
. |
V | L | H | G | A | S | G | L | S | T | K | D | I | Q | Q | T | I | K |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |
|
|   |   |
|
|
|
|   |
|
|
|
|
|
|
|   |
|
|   |
|   |   |   |
|   |
|
|   |   |   |
|   |   |
|   |   |   |   |   |
|
|
| . | . |
|
|
|
|
|
|
|   |   |   |
|   |   |   |   |
|
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |
|
|   |   | . |
|
|
|
|   |
|   |
| . | . | . | . | . |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | R | A | Q | A | Y | V | D | . |
A | G | A | D | M | L | F | P | . |
. |
. |
. |
. |
E | A | I | T | . |
. |
. |
. |
. |
. |
E | L | S | M | Y | R | R | F | A | D | V | A | Q | V | P | I | L | A | N | I | T | E | F | G | A | T | P | L | F | T | T | D | E | L | R | S |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  | . | T | T |
| S |  |  |  |  | . | . | . | . | . |
| S |
|
| . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
| S |
| B |  |  |  |
|
| S | S | S | S | S |
|
|
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  | . | . | . | . | . |
|
|
|
| . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
172 | . | . | . | . | . | . | . | |
180 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 190 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . |
  |
  |   |
224 | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | G | I | C | K | I | N | V | A | T | E | L | K | N | A | F | S | Q | A | L | K | N | Y | L | T | E |
Query Conservation |   |
  |
|
|   |
|
|
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
A | H | V | A | M | A | L | Y | P | L | S | A | F | R | A | M | N | R | A | A | E | K | V | Y | T | V |
Template Known Secondary structure |   |
T | T |
|
|  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
228 | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . |
  |