Job Description P0C8J6 Confidence 97.44% Date Thu Jan 5 11:30:05 GMT 2012 Rank 52 Aligned Residues 191 % Identity 14% Template c2cw6B_ PDB info PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Resolution 2.10 Å

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		26	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	N	L	E	T	M	Q	V	V	V	E	T	A	A	N	L	H	A	P	V	I	I	A	G	T	P	G	T	F	T	H	A	G	T	E	N	L	L	A	L	V	S	A	M	A	K	Q	Y	H	H	P	L	A	I	H	L	D	H	H	T	K	F	D	D	I	A	Q	K	V	R	S	G	V	R	S	V	M	I	D	A
Query Conservation
Alig confidence																																																											.	.
Template Conservation																																																											.	.
Template Sequence		V	S	T	P	V	K	I	K	L	I	D	M	L	S	E	A	G	L	S	V	I	E	T	T	S	F	V	S	P	K	W	V	P	Q	M	G	D	H	T	E	V	L	K	G	I	Q	K	F	P	G	I	N	Y	P	V	L	T	.	.	P	N	L	K	G	F	E	A	A	V	A	A	G	A	K	E	V	V	I	F	G
Template Known Secondary structure																	T	T		S										T	T	T		G	G	G	T	T								S				T	T		B						.	.		S										T	T		S
Template Predicted Secondary structure																																																											.	.
Template SS confidence
		51	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.			.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.
		106	.	.	.	110											.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.				.	.	.	.	170	.	.
Predicted Secondary structure							.	.	.	.	.	.	.	.	.	.																																																								.	.	.
Query SS confidence							.	.	.	.	.	.	.	.	.	.																																																								.	.	.
Query Sequence		S	H	L	P	F	.	.	.	.	.	.	.	.	.	.	A	Q	N	I	S	R	V	K	E	V	V	D	F	C	H	R	F	D	V	S	V	E	A	E	L	G	Q	L	G	G	Q	E	D	D	V	Q	V	N	E	A	D	A	L	Y	T	N	P	A	Q	A	R	E	F	A	E	.	.	.	A	T	G	I	D	S	L
Query Conservation							.	.	.	.	.	.	.	.	.	.																																																								.	.	.
Alig confidence							.	.	.	.	.	.	.	.	.	.																																				.	.	.	.	.	.	.	.													.	.	.							.
Template Conservation																																																				.	.	.	.	.	.	.	.																						.
Template Sequence		A	A	S	E	L	F	T	K	K	N	I	N	C	S	I	E	E	S	F	Q	R	F	D	A	I	L	K	A	A	Q	S	A	N	I	S	V	R	G	Y	V	S	C	A	L	G	C	P	Y	E	G	.	.	.	.	.	.	.	.	K	I	S	P	A	K	V	A	E	V	T	K	K	F	Y	S	M	G	C	Y	E	.
Template Known Secondary structure			S									T	S	S		T	T	T															T	T									S	T	T		B	T	T	T	B	.	.	.	.	.	.	.	.	S																T	T		S		.
Template Predicted Secondary structure																																																				.	.	.	.	.	.	.	.																						.
Template SS confidence
		129	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.									.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.
		173	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.		.	.	.	.	.	.	.	.	210	.			.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230
Predicted Secondary structure																															.											.	.
Query SS confidence																															.											.	.
Query Sequence		A	V	A	I	G	T	A	H	G	M	Y	A	S	A	P	A	L	D	F	S	R	L	E	N	I	R	Q	W	V	.	N	L	P	L	V	L	H	G	A	S	.	.	G	L	S	T	K	D	I	Q	Q	T	I	K	L	G	I	C	K	I	N
Query Conservation																															.											.	.
Alig confidence		.										.	.																		.											.	.
Template Conservation		.										.	.
Template Sequence		.	I	S	L	G	D	T	I	G	V	.	.	G	T	P	G	I	M	K	D	M	L	S	A	V	M	Q	E	V	P	L	A	A	L	A	V	H	C	H	D	T	Y	G	Q	A	L	A	N	T	L	M	A	L	Q	M	G	V	S	V	V	D
Template Known Secondary structure		.						T	T			.	.																	S		G	G	G						B		T	T	S												T	T
Template Predicted Secondary structure		.										.	.
Template SS confidence
			200	.	.	.	.	.	.	.	.			.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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