|   |
28 | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
D | F | V | V | I | H | I | P | D | Q | I | G | D | A | M | A | I | F | P | V | I | R | A | L | E | L | H | K | I | K | H | L | L | I | V | T | S | T | I | N | L | E | V | F | N | A | L | K | L | E | Q | T | K | L | T | L | V | T | M | T | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |
|
|
|   |   |
|   |   |
|
|
|   |
|   |   |   |
|   |
|
|
|
|
|   |   |
|   |   |   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|
|
|   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|   |   |
|   |   |
| . |
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
X | R | V | L | F | A | S | L | G | T | H | G | H | T | Y | P | L | L | P | L | A | T | A | A | R | A | A | . |
G | H | E | V | T | F | A | T | G | E | G | F | A | G | T | L | R | K | L | G | F | E | P | V | A | T | G | X | P | V | F | D | G | F | L | A | A | L | R | I | R | F | D | T | D | S | P | E | G | L | T | P |
Template Known Secondary structure |   |
|  |  |  |  |  |
|
| S | S |  |  |  |  | G | G | G |  |  |  |  |  |  |  |  |  | T | . | T |
|  |  |  |  |  |  |
| G | G | G |  |  |  |  |  |  | T | T |
|  |  |  |  |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| S |
|
| T | T |
|
|  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | |
. | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
89 | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | D | H | A | T | L | K | E | I | K | D | L | A | K | N | I | T | Q | Q | Y | G | T | P | D | L | C | I | E | G | M | R | K | K | N | L | K | T | M | L | F | I | S | Q | L | K | A | K | T | N | F | Q | V | V | G | I | T | M | N | C | F | S | P | L | C | K | N | A | S | S | M | D |
Query Conservation |   |
. | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | Q | L | S | E | L | P | Q | I | V | F | G | R | V | I | P | Q | R | V | F | D | E | L | Q | P | V | I | E | R | L | R | P | D | L | V | V | Q | E | I | S | N | Y | G | A | G | L | A | A | L | K | A | G | I | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | I | C | H | G | V | G | R | D | T | P |
Template Known Secondary structure |   |
 |  |  | T | T |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  | T |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
| S |
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 140 | . | . | . | . |
  |
  |   |
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | K | L | R | A | P | V | P | M | T | W | A | F | M | M | R | E | A | G | F | P | A | V | R | P | I | Y | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | P | L | S | E | D | V | L | D | E | V | R | E | E | M | R | S | L | G | S | Y |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | D | L | T | R | S | I | E | E | E | V | R | G | L | A | Q | R | L | G | L | D | L | P | P | G | R | I | D | G | F | G | N | P | F | I | D | I | F | P | P | S | L | Q | E | P | E | F | R | A | R | P | R | R | H | E | L | R | P | V | P | F | A | E | Q | G | D | L | P | A | W | L | S | S | R | D | T | A | R | P | L |
Template Known Secondary structure |   |
S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
| S | S |
|
| G | G | G | G |
|
|  |  |  |
| S |
| T | T | T | S |
|  |  |  |  | T |
| T | T |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| G | G | G | G | G | S |
| T | T | S |
|  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
145 | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . |
  |
  |   |
209 | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | A | F | N | L | E | G | S | S | Q | E | R | T | F | S | L | S | I | A | E | N | L | I | A | K | I | Q | S | E | T | D | I | P | I | V | I | V | H | G | P | K | G | E | D | K | A | R | A | L | V | D | C | Y | N | N | V | Y | R | L | S | L | P | P | S | I | K | R | S | A | A | I | I | K | D | A | Y | I | A | I | T |
Query Conservation |   |
|   |
|   |
|
|
|
|   |   |   |
|   |
|
|   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|   |
|
|   |   |
|
|   |   |
|   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
V | Y | L | T | L | G | T | S | S | G | G | . |
. |
. |
T | V | E | V | L | R | A | A | I | D | G | L | A | G | L | D | A | D | V | L | V | A | S | G | P | S | L | D | V | S | . |
. |
. |
. |
G | L | G | E | V | P | A | N | V | R | L | E | S | W | V | P | Q | A | A | . |
. |
. |
L | L | P | H | V | D | L | V | V | H |
Template Known Secondary structure |   |
 |  |  |  |
| T | T | T | T | S |
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  | T | S | S | S |  |  |  |  |  |
| T | T | T |
|
|
| T | . | . | . | . | T |
|
|
|
|
| T | T |  |  |  |  | S |
|
|
|  |  |  | . | . | . |  | G | G | G |
| S |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  | . | . | . | . |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
225 | . | . | . | . | 230 | . | . | . | . | . | |
|
|
. | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | |
|
|
|
. | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | |
|
|
. | . | . | . | . | 290 | . | . | . | . |
  |
  |   |
289 | 290 | . | . | . | |
. | . | . | . | . | . | 300 | . | . | . | . | . | . | . | |
|
. | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  | . |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | D | T | S | I | . |
L | H | M | A | S | A | Y | N | T | P | V | V | A | I | . |
. |
Y | A | D | Y | K | T | R | W | P | A | M | A | D | V | S | E | S | V | V | V | G | Q | K | I | D | N | I | S | L | D | E | F | A | K | A | L | K | S | V | L | A | R |
Query Conservation |   |
  |
|
|
|   | . |   |
|
|
|
|
|   |   |   |
|   |
|
|
| . | . |
|
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|   |   |
|
|
|
|   |
|   |
|
|
|   |   |
|   |   |   |
|
|   |   |   |
|   |   |
|   |   |   |
|   |
|   |   |
|   |   |   | . | . |   |   |   |   |   |   |
|
|   |
|
|   |   |
|
|   |
|
Template Sequence |   |
H | G | G | S | G | T | T | L | G | A | L | G | A | G | V | P | Q | L | S | F | P | W | A | G | D | S | F | A | N | A | Q | A | V | A | Q | A | G | A | G | D | H | L | L | P | D | . |
. |
N | I | S | P | D | S | V | S | G | A | A | K | R | L | L | A | E |
Template Known Secondary structure |   |
S |
|
|  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |
|
|
| S | T | T |  |  |  |  |  |  |  |  |  |  | T | T | S |  |  |  |
|
| G | G | . | . | G |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|  |  | . | . |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
295 | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | |
|
340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . |
  |