|   |
53 | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | |
. | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | S | G | I | G | N | F | Y | S | N | L | H | P | A | L | A | D | N | V | V | Y | A | A | . |
D | R | A | G | L | V | K | A | L | N | A | D | D | G | K | E | I | W | S | V | S | L | A | E | K | D | G | W | F | S | K | E | P | A | L | L | S | G | G | V | T | V | S | G | G | H | V | Y | I | G | S | E | K | A | Q | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |
|   |   |   | . |   |   |   |
|   |
|   |
|   |
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |
|
|   |   |   |
|   |   |
|   |
|
|   |
|
|   |   |
|
|
|
|   |
|   |   |   |
Template Sequence |   |
G | A | M | G | S | K | P | A | Y | S | F | H | V | T | A | D | G | Q | M | Q | P | V | P | F | P | P | D | A | L | I | G | P | G | I | P | R | H | A | R | Q | I | N | T | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | H | G | E | V | V | C | A | V | T | I | S | N | P | T | R | H | V | Y | T | G | G | K | G | C | V |
Template Known Secondary structure |   |
|
|
|
|
|
| S |
|
|  |  |  |  |
| S | S | S |
|  |  |  |
|
|
|
| T | T | S | S | S | S | T | T |
|
| S |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
|
| S | S |
|
|
|  |  |  |  |
| S | S | S | S |  |  |  |  |  |
| B | S |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
438 | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . |
  |
  |   |
132 | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |
|
|
| . | . | . | . | . | . |
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | A | L | N | T | S | D | G | T | V | A | W | Q | T | K | . |
. |
. |
. |
. |
. |
V | A | G | E | A | L | S | R | P | V | V | S | D | G | L | V | L | I | H | T | S | N | G | Q | L | Q | A | L | N | E | A | D | G | A | V | K | W | T | V | N | L | D | M | P | S | L | S | L | R | G | E | S | A | P | T | T | A | F | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | V | W | D | I | S | H | P | G | N | K | S | P | V | S | Q | L | D | C | L | N | R | D | N | Y | I | R | S | C | K | L | L | P | D | G | C | T | L | I | V | G | G | E | A | S | T | L | S | I | W | D | L | A | A | P | R | I | K | A | E | L | T | S | S | A | P | A | . |
. |
C | Y | A | L | A | I | S | P | D | S | K |
Template Known Secondary structure |   |
 |  |  |  | T | T | S | T | T |
|
| S |
| S |  |  |  |  |
| S |
| T | T | S | B |  |  |  |  |  |  |
| T | T | S | S |  |  |  |  |  |  | S | S | S |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
| S | S | S |
| . | . |  |  |  |  |  |  |
| T | T | S | S |
Template Predicted Secondary structure |   |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
508 | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | |
|
. | . | . | . | . | 580 | . | . | . | . | . |
  |
  |   |
206 | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | A | V | V | G | G | D | N | G | R | V | S | A | V | L | M | E | Q | G | Q | M | I | W | Q | Q | R | I | S | Q | A | T | G | S | T | E | I | D | R | L | S | D | V | D | T | T | P | V | V | V | N | G | V | V | F | A | L | A | Y | N | G | N | L | T | A | L | D | L | R | S | G | Q | I | M | W | K | R | E | L | G | S |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | C | F | S | C | C | S | D | G | N | I | A | V | W | D | L | H | N | Q | T | L | V | R | Q | F | Q | G | H | T | D | G | A | S | C | I | D | I | S | N | D | G | T | K | L | W | T | G | G | L | D | N | T | V | R | S | W | D | L | R | E | G | R | Q | L | Q | Q | H | D | F | T | S | Q | I | F | S | L | G | Y | C | P |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T | S |
|  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |
|
|
| S | S |
|  |  |  |  |  |  |
| T | T | S | S |  |  |  |  |  |  | T | T | S |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |
| T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
588 | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . |
  |
  |   |
286 | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | N | D | F | I | V | D | G | N | R | I | Y | L | V | D | Q | N | D | R | V | M | A | L | T | I | D | G | G | V | T | L | W | T | Q | S | D | L | L | H | R | L | L | T | S | P | V | L | Y | N | G | N | L | V | V | G | D | S | E | G | Y | L | H | W | I | N | V | E | D | G | R | F | V | A | Q | Q | K | V | D | S | S |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |
|
|
|   |
|
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
T | G | E | W | L | A | . |
. |
. |
. |
. |
. |
V | G | M | E | S | S | N | V | E | V | L | H | V | N | K | P | D | K | Y | Q | L | H | L | H | E | S | C | V | L | S | L | K | F | A | Y | C | G | K | W | F | V | S | T | G | K | D | N | L | L | N | A | W | R | T | P | Y | G | A | S | I | F | Q | S | K | E | S | S | S |
Template Known Secondary structure |   |
T | S | S |  |  |  | . | . | . | . | . | . |  |  |  | T | T | S |
|  |  |  |  |  | T | T | S | S |
|  |  |  |  |
|
|
| S | S |
|  |  |  |  |  |  |
| T | T | S | S |  |  |  |  |  |  | T | T | S |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |
| S | S |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
668 | . | 670 | . | . | . | |
|
|
|
|
|
. | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . |
  |
  |   |
366 | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | F | Q | T | E | P | V | A | A | D | G | K | L | L | I | Q | A | K | D | G | T | V | Y | S | I | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |
|   |
|   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |
|
|
|
|   |   |
|   |
|
|
|   |
|
|   |
|   |
|
|
|
Template Sequence |   |
V | L | S | C | D | I | S | V | D | D | K | Y | I | V | T | G | S | G | D | K | K | A | T | V | Y | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
742 | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . |
  |