|   |
68 | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | |
|
|
. | . | . | . | . | . | . | . | . | 140 | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
| . | . | . |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | D | N | V | V | Y | A | A | D | R | A | G | L | V | K | A | L | N | A | D | D | G | K | E | I | W | S | V | S | L | A | E | K | D | G | W | F | S | K | E | P | A | L | L | S | G | G | V | T | V | S | G | G | H | V | Y | I | G | S | E | K | A | Q | . |
. |
. |
V | Y | A | L | N | T | S | D | G | T | V | A | W | Q |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   | . | . |   |   |   |   |   |   |   | . |   |
|   |   |
|
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   | . | . | . |   |
|
|
|
|   |   |
|
|
|   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |
|
Template Sequence |   |
A | K | G | D | V | I | . |
. |
T | L | N | F | E | T | F | . |
V | D | S | D | T | Q | V | K | V | T | R | L | T | P | T | D | I | I | C | H | R | N | Y | F | Y | Q | K | C | . |
. |
. |
F | T | Q | D | G | K | K | L | L | F | A | G | D | F | D | G | N | R | N | Y | Y | L | L | N | L | E | T | Q | Q | A | V | Q | L |
Template Known Secondary structure |   |
| T | T |
|  |  | . | . |  |
|
|
|  |  |  | . |  |
| T | T | T |
|
|  |  |  |  |
| S |
| T | T | S |
|  |  |
|
|
| T | T | S |
|
| . | . | . | B |
| T | T | S |
|  |  |  |  |  |  |
| T | T | S | S |
|  |  |  |  |  |  | T | T | T | T |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|  |  |  | . | . |  |  |
|
|  |  |  | . |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|  | . | . | . |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | |
|
. | . | 10 | . | . | . | . | |
. | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | |
|
|
. | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . |
  |
  |   |
145 | . | . | . | . | 150 | . | . | . | . | . | . | |
. | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | |
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
| . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
T | K | V | A | G | E | A | L | S | R | P | V | . |
V | S | D | G | L | V | L | I | H | T | S | N | G | Q | L | Q | A | L | N | E | A | D | G | A | V | K | W | T | V | N | L | D | M | P | S | L | S | L | R | G | E | S | A | P | T | T | A | F | G | A | A | V | V | G | G | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
T | E | G | K | G | D | N | T | F | G | G | F | I | S | T | D | E | R | A | F | F | Y | V | K | N | E | L | N | L | X | K | V | D | L | E | T | L | E | E | Q | V | I | Y | T | V | D | E | E | W | K | G | Y | G | T | W | V | A | N | S | D | C | T | K | L | V | G | I | E | I | L | K | R | D | W | Q | P | L | T | S | W |
Template Known Secondary structure |   |
|
| S | S |
| B |
| T | T | T |
|  |  |
| T | T | S | S |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |
|
| T | T |  |  |  |  |  |  |  |  |  |
| T | T | S | S |  |  |  |  |  |  |  |  | G | G | G |
|
|
|
|
| S |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
76 | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
213 | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | G | R | V | S | A | V | L | M | E | Q | G | Q | M | I | W | Q | Q | R | I | S | Q | A | T | G | S | T | E | I | D | R | L | S | D | V | D | T | T | P | V | V | V | N | G | V | . |
. |
. |
. |
. |
. |
. |
V | F | A | L | A | Y | N | G | N | L | T | A | L | D | L | R | S |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | K | F | A | E | F | Y | H | T | N | P | T | C | R | L | I | K | V | D | I | E | T | G | E | L | E | V | I | H | Q | D | T | A | W | L | G | H | P | I | Y | R | P | F | D | D | S | T | V | G | F | C | H | E | G | P | H | D | L | V | D | A | R | X | W | L | V | N | E | D | G | S | N | V | R | K | I | K | E | H | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T |
|
|
|  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  | S | S |
|  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |
| S |
| S | S | S |
| S |
|
|
|  |  |  |  | T | T | S |
|
|
|  |  | S | S |
|
|
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
156 | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . |
  |
  |   |
275 | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | Q | I | M | W | K | R | E | L | G | S | V | N | D | F | I | V | D | G | N | R | I | Y | L | V | D | Q | N | D | R | V | M | A | L | T | I | D | G | G | V | T | L | W | T | Q | S | D | L | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
H | R | L | L | T | S | P | V | L | Y | N | G | N | L | V | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | G | E | S | C | T | H | E | F | W | I | P | D | G | S | A | X | A | Y | V | S | Y | F | K | G | Q | T | D | R | V | I | Y | K | A | N | P | E | T | L | E | N | E | E | V | X | V | X | P | P | C | S | H | L | X | S | N | F | D | G | S | L | X | V | G | D | G | C | D | A | N | I | E | N | D | P | F | L | Y | V | L |
Template Known Secondary structure |   |
T | T |  |  |  |  |  |  |  |  |
| T | T | S | S |
|  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |
| T | T | T |
|
|  |  |  |  |  |  |
|
| S |  |  |  |  |  |  |
| S | S | S | S |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
236 | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . |
  |
  |   |
340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | |
|
. | . | 380 | . | . | . | . | . | |
|
. | . | . | . | 390 | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  | . | . |  |  |  |  |  |
|
|
| . | . |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
Query Sequence |   |
G | D | S | E | G | Y | L | H | W | I | N | V | E | D | G | R | F | V | A | Q | Q | K | V | D | S | S | G | F | Q | T | E | P | V | A | A | D | G | K | . |
. |
L | L | I | Q | A | K | D | G | . |
. |
T | V | Y | S | I | T |
Query Conservation |   |
  |   |   |   |
|   |
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   | . | . |
|   |
|   |   |   |   |
| . | . |   |
|   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|
Template Sequence |   |
N | T | K | A | K | S | A | Q | K | L | C | K | H | S | T | S | W | D | V | L | D | G | D | R | Q | I | T | H | P | H | P | S | F | T | P | N | D | D | G | V | L | F | T | S | D | F | E | G | V | P | A | I | Y | I | A | D |
Template Known Secondary structure |   |
 | T | T | T | T | B |
|
|  |  |  |  |
|
|
|
|
|
|
| B | T | T | B | S | S | T | T |
|
|
|
|  |  |
| T | T | S | S |  |  |  |  |  |  |
| T | T | S | S |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
326 | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . |
  |