|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | N | A | E | L | A | I | G | I | D | L | G | T | T | N | S | L | I | A | V | W | K | D | G | A | A | Q | L | I | P | N | K | F | G | E | Y | L | T | P | S | I | I | S | M | D | E | N | N | H | I | L | V | G | K | P | A | V | S | R | R | T | S | H | P | D | K | T | A | A | L | F | K | R | A | M | G | S | N | T | N |
Query Conservation |   |
  |   |   |   |   |
|
|
|
|
|   |
|
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|
|
|
|   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
| . | . | . | . | . | . | . | . |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |
Template Sequence |   |
E | D | E | T | T | A | L | V | C | D | N | G | S | G | L | V | K | A | G | F | A | G | D | D | A | P | R | A | V | . |
. |
. |
. |
. |
. |
. |
. |
F | P | S | I | V | G | R | P | R | H | Q | G | V | M | V | G | M | G | Q | K | D | S | Y | V | G | D | E | A | Q | S | K | R | G | I | . |
. |
. |
. |
. |
L | T | L | K |
Template Known Secondary structure |   |
T | T | T | T | T |
|  |  |  |  |  |
| S | S |  |  |  |  |  |  | T | T |
| S | S |
| S |  |  | . | . | . | . | . | . | . | . |  |  |
|
|  |  |  |  | S | S |
|
|
|
| T | T |
|
|
|
| S |
|  |  | T |  |  |  |  |  | T | G | G | G | . | . | . | . | . |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|  |  |  |  |
|
|
|
|
| . | . | . | . | . |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | |
|
|
|
|
. | . | . | . |
  |
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | |
. | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | R | L | G | S | D | T | F | N | A | P | E | L | S | S | L | V | L | R | S | L | K | E | D | A | E | E | F | L | Q | R | P | I | K | D | V | V | I | S | V | P | A | Y | F | S | D | E | Q | R | K | H | T | R | L | . |
A | A | E | L | A | G | L | N | A | V | R | L | I | N | E | P | T | A | A | A | M | A | Y | G | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   | . |
|   |   |   |
|
|   |   |   |   |   |
|
|   |
|   |   |
|
|
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
| . |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|
|   |
|
|
|   |   |   |
|   |
Template Sequence |   |
Y | P | I | E | H | G | I | I | T | N | W | D | D | M | E | K | I | W | H | H | T | F | Y | N | E | L | . |
R | V | A | P | E | E | H | P | T | L | L | T | E | A | P | L | N | P | K | A | N | R | E | K | M | T | Q | I | M | F | E | T | F | N | V | P | A | M | Y | V | A | I | Q | A | V | L | S | L | Y | A | S | G | R |
Template Known Secondary structure |   |
| S |  |  | T | T |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | . |
|
|
| G | G | G | S |
|  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
69 | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | |
. | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . |
  |
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | |
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
Query Sequence |   |
H | T | Q | Q | N | T | R | S | L | V | F | D | L | G | G | G | T | F | D | V | T | V | L | E | Y | A | T | P | V | I | E | V | H | A | S | A | G | D | N | F | L | G | G | E | D | F | T | H | M | L | V | D | E | V | L | K | R | A | D | V | A | R | T | T | L | N | E | S | E | L | A | A | L | Y | A | C | . |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |
|
|
|   |
|   |
|   |
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|
|
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
. | . | . | . | . |   |   |   |
|
|
|
|   |
|   |   |   |
|   |
|   |   |
|   | . | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
T | T | G | I | V | L | D | S | G | D | G | V | T | H | N | V | P | I | Y | . |
. |
. |
E | G | Y | A | L | P | H | A | I | M | R | L | D | L | A | G | R | D | L | T | D | Y | L | M | K | I | L | T | E | R | G | Y | S | F | V | T | T | A | E | R | E | I | V | R | D | I | K | E | K | L | C | Y | V |
Template Known Secondary structure |   |
. | . | . | . | . | S | S |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  | . | . | . | T | T |  |  |
| G | G | G |
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template Predicted Secondary structure |   |
. | . | . | . | . |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | . | . | . |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
148 | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | |
|
|
. | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
237 | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | |
|
. | . | . | . | . | . | 300 | . |
Predicted Secondary structure |   |
. | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |  |  |  |
|
|  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
V | E | A | A | K | C | S | N | Q | S | P | L | H | I | R | W | Q | Y | Q | E | E | T | R | E | C | E | F | Y | E | N | E | L | E | . |
. |
. |
. |
. |
. |
. |
. |
D | L | W | L | P | L | L | N | R | L | R | V | P | I | E | Q | A | L | R | D | A | R | L | K | . |
. |
P | S | Q | I | D | S | L | V |
Query Conservation |   |
. | . | . | . | . |   |
|   |   |
|   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
| . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   | . | . |   |   |   |
|   |   |
|   |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   | . |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
Template Sequence |   |
A | L | D | F | E | N | E | M | A | T | A | A | S | S | S | S | L | E | K | S | Y | E | L | P | . |
D | G | Q | V | I | T | I | G | N | E | R | F | R | C | P | E | T | L | F | Q | P | S | F | I | G | M | E | S | A | G | I | H | E | T | T | Y | N | S | I | M | K | C | D | I | D | I | R | K | D | L | Y | A | N | N | V |
Template Known Secondary structure |   |
| S | S | S |  |  |  |  |  |  |  |  |  |
|
| T | T |
|  |  |  |  |
| S | . | S | S |
|  |  |  |  | S | S |  |  |  |  | T | T |  |  |  |  |
| G | G | G | G | T |
|
| S |
|
|  |  |  |  |  |  |  |  |  | T | T | S |
| T | T | T |  |  |  |  |  | T |
|  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
| . |
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | |
. | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . |
  |
  |   |
302 | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | V | G | G | A | S | Q | M | P | L | V | Q | R | I | A | V | R | L | F | G | . |
. |
. |
. |
. |
. |
. |
. |
K | L | P | Y | Q | S | Y | D | P | S | T | I | V | A | L | G | A | A | I | Q | A | A | C |
Query Conservation |   |
|
|
|
|   |
|   |   |
|   |
|   |   |   |
|   |   |   |
|   | . | . | . | . | . | . | . | . |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|   |
|   |
|
|
|
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|   |   |   |   |
Template Sequence |   |
M | S | G | G | T | T | M | Y | P | G | I | A | D | R | M | Q | K | E | I | T | A | L | A | P | S | T | M | K | I | K | I | I | A | P | P | E | R | K | Y | S | V | W | I | G | G | S | I | L | A | S | L |
Template Known Secondary structure |   |
 |  | S | G | G | G | G | S | T | T |  |  |  |  |  |  |  |  |  |  | T | T | S |
| T | T | S |
|
|
|  |  |
|
| T | T | G | G | G |  |  |  |  |  |  |  |  |  |  |  | S |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
299 | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . |
  |