Job Description P0ABQ4 Confidence 100.00% Date Thu Jan 5 11:16:05 GMT 2012 Rank 18 Aligned Residues 156 % Identity 35% Template c3dg8B_ PDB info PDB header:oxidoreductase, transferase Chain: B: PDB Molecule:bifunctional dihydrofolate reductase-thymidylate PDBTitle: quadruple mutant (n51i+c59r+s108n+i164l) plasmodium2 falciparum dihydrofolate reductase-thymidylate synthase3 (pfdhfr-ts) complexed with rjf670, nadph, and dump Resolution 2.58 Å

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		2	.	.	.	.	.	.	.	10	.																		.	.	.	.	.	.	.	.	20	.	.	.		.	.	.	.	.	.	30	.	.	.	.	.	.																									.	.	.
Predicted Secondary structure												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.													.														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.													.														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		I	S	L	I	A	A	L	A	V	D	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	R	V	I	G	M	E	N	A	M	P	W	N	.	L	P	A	D	L	A	W	F	K	R	N	T	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	N	K	P
Query Conservation												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.													.														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.													.														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		I	Y	A	I	C	A	C	C	K	V	E	S	K	N	E	G	K	K	N	E	V	F	N	N	Y	T	F	R	G	L	G	N	K	G	V	L	P	W	K	C	I	S	L	D	M	K	Y	F	R	A	V	T	T	Y	V	N	E	S	K	Y	E	K	L	K	Y	K	R	C	K	Y	L	P	N	S	K	K	L	Q	N	V
Template Known Secondary structure														T	T				S	S					G	G	G						B	T	T	B		S	S	S																		T	T	T	S								G	G	G						S
Template Predicted Secondary structure
Template SS confidence
		11	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90
		40	.	.	.	.	.	.	.	.	.	50	.				.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.				.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.			.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.			.	.	.
Predicted Secondary structure														.	.	.																		.	.	.																					.	.																			.	.
Query SS confidence														.	.	.																		.	.	.																					.	.																			.	.
Query Sequence		V	I	M	G	R	H	T	W	E	S	I	G	.	.	.	R	P	L	P	G	R	K	N	I	I	L	S	S	Q	P	G	T	.	.	.	D	D	R	V	T	W	V	K	S	V	D	E	A	I	A	A	C	G	D	V	.	.	P	E	I	M	V	I	G	G	G	R	V	Y	E	Q	F	L	P	K	.	.	A	Q	K
Query Conservation														.	.	.																		.	.	.																					.	.																			.	.
Alig confidence														.	.	.																		.	.	.																					.	.																			.	.
Template Conservation
Template Sequence		V	V	M	G	R	T	N	W	E	S	I	P	K	K	F	K	P	L	S	N	R	I	N	V	I	L	S	R	T	L	K	K	E	D	F	D	E	D	V	Y	I	I	N	K	V	E	D	L	I	V	L	L	G	K	L	N	Y	Y	K	C	F	I	L	G	G	S	V	V	Y	Q	E	F	L	E	K	K	L	I	K	K
Template Known Secondary structure												S		S	T	T		S		T	T								S	S			T	T	T	S		S	S	S				S	S	T	T								T	S																				T	T			S
Template Predicted Secondary structure
Template SS confidence
		102	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.
		110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	Y	L	T	H	I	D	A	E	V	E	G	D	T	H	F	P	D	Y	E	P	D	D	W	E	S	V	F	S	E	F	H	D	A	D	A	Q	N	S	H	S	Y	C	F	E	I	L	E	R	R
Query Conservation
Alig confidence																														.	.
Template Conservation																														.	.
Template Sequence		I	Y	F	T	R	I	N	S	T	Y	E	C	D	V	F	F	P	E	I	N	E	N	E	Y	Q	I	I	S	.	.	V	S	D	V	Y	T	S	N	N	T	T	L	D	F	I	I	Y	K	K	T
Template Known Secondary structure														S								T	T	T						.	.								T	T
Template Predicted Secondary structure																														.	.
Template SS confidence
		182	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.			210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions