|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | |
|
. | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
Query Sequence |   |
K | Q | Y | L | I | A | P | S | I | L | S | A | . |
. |
D | F | A | R | L | G | E | D | T | A | K | A | L | A | A | G | A | D | V | V | H | F | D | V | M | D | N | H | Y | V | P | N | L | T | I | G | P | M | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | K | S | L | R | N | Y |
Query Conservation |   |
|
|   |   |
|   |
|   |
|   |   |   | . | . |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|
|
|
|
| . | . | . |
|
|
|
|
|   |
|
|
|
|   |
|
|   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
R | E | K | A | L | V | S | Y | L | M | V | G | Y | P | D | Y | E | T | S | L | K | A | F | K | E | V | L | K | N | G | T | D | I | L | E | I | G | F | . |
. |
. |
P | F | S | D | P | V | A | D | G | P | T | I | Q | V | A | H | E | V | A | L | K | N | G | I | R | F | E | D | V | L | E | L | S | E | T | L | R | K | E |
Template Known Secondary structure |   |
T | B |
|  |  |  |  |  |  |  | T | T | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |
| . | . | . |
|
| S |
|
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
| . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
15 | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | |
|
|
. | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . |
  |
  |   |
60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | I | T | A | P | I | D | V | H | L | M | V | K | P | V | . |
. |
. |
. |
. |
D | R | I | V | P | D | F | A | A | A | G | A | S | I | I | T | F | H | P | E | A | S | E | H | V | D | R | T | L | Q | L | I | K | E | N | G | C | K | A | G | L | V | F | N | P | A | T | P | L | S | Y | L | D | Y | V | M | D | K | L | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|
|
|
|   |
|   |
|   |
|   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|   |
|   |
|   |   |   |
|
|   |   |
|   |   |   |
|   |
Template Sequence |   |
F | P | D | I | P | F | L | L | M | T | Y | Y | N | P | I | F | R | I | G | L | E | K | F | C | R | L | S | R | E | K | G | I | D | G | F | I | V | P | D | L | P | P | E | E | A | E | E | L | K | A | V | M | K | K | Y | V | L | S | F | V | P | L | G | A | P | T | S | T | R | K | R | I | K | L | I | C | E | A | A | D |
Template Known Secondary structure |   |
| T | T | S |
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |
|
|  |  |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |
| S |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
92 | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . |
  |
  |   |
135 | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | |
|
. | . | . | . | 210 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
Query Sequence |   |
V | I | L | L | M | S | V | N | P | G | F | G | G | Q | S | F | I | P | Q | T | L | D | K | L | R | E | V | R | R | R | I | D | E | S | G | F | D | I | R | L | E | V | D | G | G | V | K | V | N | N | I | G | E | I | A | A | A | G | A | D | M | F | V | A | G | S | A | I | F | D | Q | . |
. |
P | D | Y | K | K | V | I |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|
|
|
|
|   |   |
| . | . |   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|   |   |
|   |   |
|   |
|
| . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|
|   |
|
|
|
|
|   |   |   |
|   |
|   |   |
|   |   | . |
|
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
E | M | T | Y | F | V | S | V | T | G | Y | E | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | K | K | K | V | E | E | Y | R | E | L | C | D | K | P | V | V | V | G | F | G | V | S | K | K | E | H | A | R | E | I | G | S | . |
F | A | D | G | V | V | V | G | S | A | L | V | K | L | A | G | Q | K | K | I | E | D | L |
Template Known Secondary structure |   |
S |
|  |  |  |  | S | S |
|
|
|  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
| S |
|  |  |  |  | S | S |
|
| S |  |  |  |  |  |  |  |  | T | . | T | S | S |  |  |  |  |
|  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
172 | . | . | . | . | . | . | . | 180 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | |
. | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 |
  |
  |   |
213 | . | . | . | . | . | . | 220 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | E | M | R | S | E | L | A | K | V | S | H | E |
Query Conservation |   |
  |   |
|   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|
|   |
|   |   |   |
Template Sequence |   |
G | N | L | V | K | E | L | K | E | G | L | R | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | T | B |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
250 | . | . | . | . | . | . | . | . | . | 260 | . | . |
  |