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Job DescriptionP21189
Confidence100.00%DateThu Jan 5 11:38:01 GMT 2012
Rank3Aligned Residues723
% Identity22%Templatec2gv9B_
PDB info PDB header:transferaseChain: B: PDB Molecule:dna polymerase; PDBTitle: crystal structure of the herpes simplex virus type 1 dna polymerase
Resolution2.68 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   10.........20.........30 .........40......... 50.........60.........70.....
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Query Sequence  RHWRDTPQGTEVSFWLATDNG. PLQVTLAPQESVAFIPADQ. . . . . . . . . . . . . VPRAQHILQGEQGFRLTPLALKDFHR
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Template Sequence  FMDAITPTGTVITLLGLTPEGHRVAVHVYGTRQYFYMNKEEVDRHLQCRAPRDLCERMAAALRESRGISADHFEAEVVER
Template Known Secondary structure  TTSS
TTS



TTTTS
SSS





STT
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   171........180.........190.........200.........210.........220.........230.........240.........250
 
   76 ...80.........90.........100.........110........ .120.........130...
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Query Sequence  Q. . . . . . . . . . PVYGLYCRAHRQLMNYEKRLREGGVTVYEADVRPPERYLMER. FITSPVWVEGDMHNG. . . . . . . . . . .
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Template Sequence  TDVYYYETRPALFYRVYVRSGRVLSYLCDNF. CPAIKKYEGGVDATTRFILDNPGFVTFGWYRLKPGRNNTLAQPRAPMA
Template Known Secondary structure  SS
TT


S
TTS.
SS


BSTT

TSTT

SS

BTTTB



GGG
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   256...260.........270.........280...... ...290.........300.........310.........320.........330....
 
   134.....140.... .....150.........160.........170..... ....180.......
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Query Sequence  TIVNARLKPHP. . . . . . . . . . . DYRPPLKWVSIDIETTRHGELYCIGLEGCGQ. . RIVYMLGPENGD. . . . . . . . . . . . .
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Template Sequence  FGTSSDVEFNCTADNLAIEGGMSDLPAYKLMCFDIECKAGGED. ELAFPVAGHPEDLVIQISCLLYDLSTTALEHVLLFS
Template Known Secondary structure 

BS
SGGG
SS

S





SS
.TTS


TTSTTSTTT

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   335....340.........350.........360.........370....... ..380.........390.........400.........410...
 
   188.190.........200.........210.........220.........230.........240... ......
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Query Sequence  . . . . . . . . . . . . . . . . ASSLDFELEYVASRPQLLEKLNAWFANYDPDVIIGWNVVQFDLRMLQKHAERYRLP. . LRLGRD
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Template Sequence  LGSCDLPESHLNELAARGLPTPVVLEFDSEFEMLLAFMTLVKQYGPEFVTGYNIINFDWPFLLAKLTDIYKVPLDGYGRM
Template Known Secondary structure  S




TT



SS

SSSTTTTTTT



TTSSSB
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   414.....420.........430.........440.........450.........460.........470.........480.........490...
 
   250...... ...260.........270.........280.........290.........300.........310.........320.....
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Query Sequence  NSELEWR. . . . EHGFKNGVFFAQAKGRLIIDGIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDK
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Template Sequence  NGRGVFRVWDIGQSHFQKRSKIKVNGMVNIDMYGIITDK. IKLSSYKLNAVAEAVLKDKKK. DLSYRDIPAYYATGPAQR
Template Known Secondary structure  SSS




SS

TTS



BTTBTT.


S

S




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TTT
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   494.....500.........510.........520.........530.. .......540.........550... ......560.........570.
 
   326...330.........340.........350.........360...... ...370.........380.........390.........400...
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Query Sequence  PALATYNLKDCELVTQIFHKTEIMPFLLERATVNGLPVDRH. . GGSVAAFGHLYFPRMHRAGYVAPNLGEVPPHASPGGY
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Template Sequence  GVIGEYCIQDSLLVGQLFFKFLPHLELSAVARLAGINITRTIYDGQQIRVFTCLLRLADQKGFILPDT. . . . . . . . . . . .
Template Known Secondary structure 
T

SS
T
B

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   572.......580.........590.........600.........610.........620.........630.........
 
   404.....410.... .....420.........430.........440.........450.. .......460.. .......470..
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Query Sequence  VMDSRPGLYDS. VLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHSTE. . . . . . . GFLDAWFSRE. . . KHCLPEIVTN
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Template Sequence  VLDPTSGFHVNPVVVFDFASLYPSIIQAHNLCFSTLSLRADAVAHLEAGKDYLEIEVGGRRLFFVKAHVRESLLSILLRD
Template Known Secondary structure 






S
TTTT

TTTS
T




TS
TTTT

SSS

TTT


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   701........710.........720.........730.........740.........750.........760.........770.........780
 
   473......480..... ....490.........500.........510.........520.........530.......
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Query Sequence  IWHGRDEAKRQGN. . . . . . . . . . KPLSQALKIIMNAFYGVLGTTACRFFDPRLASSITMRGHQIMRQTKALIEAQ. . . . .
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Template Sequence  WLAMRKQIRSRIPQSSPEEAVLLDKQQAAIKVVCNSVYGFTGVQHGLLPCLHVAATVTTIGREMLLATREYVHARWAAFE
Template Known Secondary structure  GGGS
TT
TTSSS

TSS
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   781........790.........800.........810.........820.........830.........840.........850.........860
 
   538.540.........550.........560.........570.........580.........590.........
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Query Sequence  . . . . . . . . . . . . . . . . . . GYDVIYGDTDSTFVWLKGAHSEEEAAKIGRALVQHVNAWWAETLQKQRLTSALELEYETHFC
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Template Sequence  QLLADFPEAADMRAPGPYSMRIIYGDTDSIFVLCRG. LTAAGLTAMGDKMASHISRAL. . . . . . . . FLPPIKLECEKTFT
Template Known Secondary structure 
TTGGGTB
SS


SST.B
STT........

TT

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   861........870.........880.........890...... ...900.........910....... ..920.........930.
 
   600.........610.........620.........630.........640.........650.........660..
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Query Sequence  RFLMPTIRGADTGSKKRYAGLIQEGDKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPY. . . . . . . . . . . . . . . . .
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Template Sequence  KLLLIA. . . . . . . . KKKYIGVIYGG. . . KMLIKGVDLVRKNNCAFINRTSRALVDLLFYDDTVSGAAAALAERPAEEWLA
Template Known Secondary structure  ........TTTTS...
S

S

TTS

TTSS
GGGGGT
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   932..... ..940........ .950.........960.........970.........980.........990.........1000
 
   663......670......... 680.........690.........700.........710.........720.........730.
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Query Sequence  . . . . . . . . . . QEYVRETIDKLMAGELD. ARLVYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQNRGTIKYV
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Template Sequence  RPLPEGLQAFGAVLVDAHRRITDPERDIQDFVLTAELSRHPRAYTNKRLAHLTVYYKLMAR. . . . . RAQVPSIKDRIPYV
Template Known Secondary structure  S


GGG
SS

GGGG


S
GGG
SS


T.....T




TT
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   1001........1010.........1020.........1030.........1040.........1050.........1060. ........1070.....
 
   732. ......740.. .......750.........760.........770...
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Query Sequence  WT. . . . . . . . . . . . . . . . . . . . . . . . TNGPEPLDY. . . QRSPLDYEHYLTRQLQPVAEGILPFIEDNFA
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Template Sequence  IVAQTREVEETVARLAALRELDKLLVSELAEDPAYAIAHGVALNTDYYFSHLLGAACVTFKALFGNNAK
Template Known Secondary structure  B


TT



GGGG
TT

B
GGGGTT
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   1076...1080.........1090.........1100.........1110.........1120.........1130.........1140....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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