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Job DescriptionP0A855
Confidence99.92%DateThu Jan 5 11:06:56 GMT 2012
Rank18Aligned Residues262
% Identity15%Templatec2g5tA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   161........170...... ...180.........190.........200.........210.........220.........230.......
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Query Sequence  GAFRTRIAYVVQTNGG. . . QFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVTFESGRSALVIQTLANGAVR
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Template Sequence  SPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNN. . . . DIYVKIEPNLPSY
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   108.110.........120.........130.........140.........150.........160.........170 .........180...
 
   238.240...... ...250.........260.........270.........280.........290........
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Query Sequence  QVASFPRHN. . . . . . . . . . . . . . . . . . . GAPAFSPDGSKLAFALSKTGSLNLYVMDLASGQIRQVTDGRSNNTEPTWFPD
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Template Sequence  RITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVN
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   184.....190.........200.........210.........220.........230.........240.........250.........260...
 
   299300 .........310.........320.........330.........340.........350..... ....360.........370..
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Query Sequence  SQ. NLAFTSDQAGRPQVYKVNINGGAPQRITWEGSQNQDADVSSDGKFMVMVSSNGGQ. . . QHIAKQDLATGGVQVLS. .
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Template Sequence  PTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVAR
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   264.....270.........280.........290.........300.........310.........320.........330.........340...
 
   373......380.........390. ........400.........410.........420......
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Query Sequence  . . . . . . . . . . . STFLDETPSLAPNGTMVIY. SSSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAW
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Template Sequence  QHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEA
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   344.....350.........360.........370.........380.........390.........400.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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