|   |
289 | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | F | T | G | F | G | R | H | E | D | A | D | L | R | G | K | G | F | D | N | V | L | M | V | H | D | H | A | L | M | D | W | I | G | A | N | S | Y | R | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | H | Y | P | Y | A | E | E | M | L | D | W | A | D | E | H | G | I | V | V | I | D | E | T | A |
Query Conservation |   |
  |
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|
|
|
|   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |
|
|   |   |
|   |
|
|   |   |
|
|   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |
|
|   |   |   |
|
|   |
|
Template Sequence |   |
F | P | I | G | V | A | V | S | N | T | D | S | A | T | Y | N | L | L | T | N | S | R | E | Q | A | V | V | K | K | H | . |
. |
. |
. |
F | N | H | L | T | A | G | N | I | M | K | M | S | Y | M | Q | P | T | E | G | N | F | N | F | T | N | A | D | A | F | V | D | W | A | T | E | N | N | M | T | V | H | G | H | A | L |
Template Known Secondary structure |   |
|
|  |  |  |  |  | B |
| T | T |
| T | T | T | B | T | T | T |
|  |  |  |  |  |  |  |  |  |  | . | . | . | . |
| S |  |  |  |  | S | S | T | T | S |  |  |  |  |
| S | B | T | T | B |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
259 | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | |
|
|
|
. | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . |
  |
  |   |
354 | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
A | V | G | F | N | L | S | L | G | I | G | F | E | A | G | N | K | P | K | E | L | Y | S | E | E | A | V | N | G | E | T | Q | Q | A | H | L | Q | A | I | K | E | L | I | A | R | D | K | N | H | P | S | V | V | M | W | S | I | A | N | E | P | D | T | R | P | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|
|
|
|
|   |
|   |   |   |
|
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |
|   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | W | H | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
D | Y | Q | V | P | N | F | M | K | N | W | A | G | S | A | E | D | F | L | A | A | L | D | T | H | I | T | T | I | V | D | H | Y | E | A | K | G | N | L | V | S | W | D | V | V | N | E | A | I | D | D | N | S | P | A | N | F | R | T | T | D | S | A | F | Y | V | K |
Template Known Secondary structure |   |
 |  |
|
| . | . | . | . | . | . | . | . | . | G | G | G | S |
|  |  |  |  | T |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
| B |
| S | S | S | S |
|
| B |
|
| T | T |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
335 | . | . | . | |
|
|
|
|
|
|
|
|
. | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . |
  |
  |   |
|
|
420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . |
Predicted Secondary structure |   |
. | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
G | A | R | E | Y | F | A | P | L | A | E | A | T | R | K | L | D | P | T | R | P | I | T | C | V | N | V | M | F | C | D | A | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | D | T | I | S | D | L | F | D | V | L | C | L | N | R | Y | Y | G | W | Y | V | Q | S | G | D | L | E | T | A | E | K | V | L |
Query Conservation |   |
. | . |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|
|   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|
|
|
|   |
|   |
| . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
S | G | N | S | S | V | Y | I | E | R | A | F | Q | T | A | R | A | A | D | P | A | V | I | L | Y | Y | N | D | Y | N | I | E | Q | N | N | A | K | T | T | K | M | V | D | M | V | K | D | F | Q | A | R | S | I | P | I | D | G | V | G | F | Q | M | H | . |
. |
V | C | M | N | Y | P | S | I | A | N | I | S | A | A | M |
Template Known Secondary structure |   |
T | T | S |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |  |  |  |  |  |  | S | S | T | T | S |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |  |
|
|  | . | . |  |  | S | S |
| S |
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
| . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
406 | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | |
|
. | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . |
  |
  |   |
486 | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | |
|
|
. | . | . | . | . | . | . | . | 550 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | K | E | L | L | A | W | Q | E | K | L | H | Q | P | I | I | I | T | E | Y | G | . |
. |
. |
. |
. |
. |
. |
V | D | T | L | A | G | L | H | S | M | Y | T | D | M | W | S | E | E | Y | Q | C | A | W | L | D | M | Y | H | R | V | F | D | R | V | S | . |
. |
. |
A | V | V | G | E | Q | V | W | N | F | A | D | F | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |
| . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . | . |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   | . | . | . | . | . |   |   |
|   |
|
|   |
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |   |
|   |   |
Template Sequence |   |
K | K | V | V | . |
. |
. |
. |
. |
D | L | G | L | L | V | K | I | T | E | L | D | V | A | V | N | Q | P | H | C | D | A | Y | P | A | N | K | I | N | P | L | T | E | A | A | Q | L | A | Q | K | K | R | Y | C | D | V | V | K | A | Y | L | D | T | V | P | V | N | Q | R | G | G | I | S | V | W | G | T | T | D | A | N |
Template Known Secondary structure |   |
 |  |  |  | . | . | . | . | . | T | T | T |
|  |  |  |  |  |  |  |  |  |  | S | S |
| T | T | S | T | T | T | T | T | T |
|
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| G | G | G |  |  |  |  |  |  | S |
| S | B | G | G | G |
Template Predicted Secondary structure |   |
 |  |  |  | . | . | . | . | . |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
484 | . | . | . | |
|
|
|
|
. | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . |
  |
  |   |
556 | |
|
|
|
|
|
. | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . |
Predicted Secondary structure |   |
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | . |
. |
. |
. |
. |
. |
S | Q | G | I | L | R | V | G | G | N | K | K | G | I | F | T | R | D | R | K | P | K | S | A | A | F | L | L | Q | K | R | W | T | G | M | N | F | G | E | K |
Query Conservation |   |
  | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |
|
|
|
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
T | W | L | D | G | L | Y | R | E | Q | F | E | D | E | K | I | S | W | P | L | L | F | D | N | N | Y | N | D | K | P | A | L | R | G | F | A | D | A | L | I | G | T | Q | C | T | N | T |
Template Known Secondary structure |   |
|  |  |  |  |  | T | T | T | T | T | T | T |
|
|
|
|
|
| S | S | B |
| T | T | S |
| B |
|  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
| S |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
559 | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . |
  |