|   |
272 | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
Query Sequence |   |
R | S | V | A | V | K | G | E | Q | F | L | I | N | H | K | P | F | Y | F | T | G | F | G | R | H | E | D | A | D | L | R | G | K | G | F | D | N | V | L | M | V | H | D | H | A | L | M | D | W | I | G | A | N | S | Y | R | T | S | H | Y | P | Y | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E |
Query Conservation |   |
|   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
  |   |
|   |   |
|   |   |
|   |   |
|
|
|   |   |   |   |
|   |
|
|
|   |
|
|
| . | . | . | . | . |
|
|
|   |
|
|   |
|   |
|   |
|   |
|   |
|
|   |
|   |
|   |
|   |
|
|
|   |
|
|   |
|
|
|   |   |
|   |   |
|
|
|
|   |   |
|
|   |
Template Sequence |   |
N | I | V | T | W | D | E | H | S | L | F | V | H | G | E | R | V | V | I | F | S | G | E | V | H | P | F | . |
. |
. |
. |
. |
R | L | P | V | P | S | L | Y | L | D | V | F | H | K | I | K | A | L | G | F | N | T | V | S | F | Y | V | D | W | A | L | L | E | G | K | P | G | R | F | R | A | D | G | I | F | S | L | E |
Template Known Secondary structure |   |
S | S |  |  |  |
| S | S |
|  |  |  | T | T |  |  |  |
|  |  |  |  |  |  |
| G | G | . | . | . | . | . | G |
|
|
| G | G | G |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |
|
|  |  |  |  |
| S | B | T | T | B |
|
|
|
| G | G | G |
| S |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
44 | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . |
  |
  |   |
336 | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 410 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  | . | . | . | . | . |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
Query Sequence |   |
E | M | L | D | W | A | D | E | H | G | I | V | V | I | D | E | T | A | A | V | G | F | N | L | S | L | G | I | G | F | E | A | G | N | K | P | K | E | L | Y | S | E | E | A | V | N | G | E | T | Q | Q | A | H | L | Q | A | I | K | E | L | I | A | R | D | K | N | H | P | S | . |
. |
. |
. |
. |
V | V | M | W | S | I |
Query Conservation |   |
  |   |   |
|   |
|
|
|   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|
|
| . | . | . | . | . |
|
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |
|
|   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |   |
|
|
|
|   |
|
|   |   |   |   |   | . |   |   |
|
|   |
|
|   |
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |
|
|
|
|
|   |   |
|
|
Template Sequence |   |
P | F | F | E | A | A | T | K | A | G | I | Y | L | L | A | R | P | G | P | Y | I | N | A | E | V | S | G | G | G | F | P | G | W | L | Q | R | V | K | G | . |
K | L | R | T | D | A | P | D | Y | L | H | A | T | D | N | Y | V | A | H | I | A | S | I | I | A | K | A | Q | I | T | N | G | G | P | V | I | L | Y | Q | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  | S |
|
|
| T | T | B | G | G | G | G |
|
| G | G | G | G | G |
|
| S | . |
| T | T | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | B | G | G | G | T | S | S |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
| . |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
119 | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | |
. | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . |
  |
  |   |
411 | . | . | . | . | . | . | . | . | 420 | |
|
|
|
. | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | |
. | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | |
|
. | . | . | . | 480 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
A | N | E | P | D | T | R | P | Q | G | . |
. |
. |
. |
A | R | E | Y | F | A | P | L | A | E | A | T | R | K | L | D | P | T | R | P | I | T | C | V | N | V | M | F | C | D | A | H | T | D | T | . |
I | S | D | L | F | D | V | L | C | L | N | R | Y | Y | G | W | Y | V | Q | S | . |
. |
G | D | L | E | T | A | E | K |
Query Conservation |   |
  |
|
|   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |
|
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | N | E | Y | S | G | A | A | E | G | V | L | F | P | N | K | P | Y | M | Q | Y | V | I | D | Q | A | R | N | A | G | I | I | V | P | L | I | N | N | D | A | F | P | G | G | T | G | A | P | G | T | G | L | G | S | V | D | I | Y | G | H | D | G | Y | P | L | G | F | D | C | A | H | P | S | A | W | P | D | N | G | L |
Template Known Secondary structure |   |
S | S |
|
|
|
| B |
| T | T | S |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |
| B | B |
|
| B | S | S | S |
|
| T | T |
| T | T | S |
| T | T |
|
| S | B |
|  |  |  |  |
| T | T |
| S |
|
| S |
| T | T |
|
|
| T | T |
| S |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
198 | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . |
  |
  |   |
484 | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | E | K | E | L | L | A | W | Q | E | K | L | H | Q | P | I | I | I | T | E | Y | G | V | D | T | L | A | G | L | H | S | M | Y | T | D | M | W | S | E | E | Y | Q | C | A | W | L | D | M | Y | H | R | V | F | D | R | V | . |
. |
. |
. |
. |
. |
. |
S | A | V | V | G | E | Q | V | W | N | F | A | D | F | A | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |
|
|   |
|
|
|
|
|
|
|   |   |   |   |   |   |
Template Sequence |   |
P | T | T | W | R | Q | D | H | L | N | I | S | P | S | T | P | F | S | L | V | E | F | Q | G | G | A | F | D | P | F | G | G | W | G | F | E | Q | C | S | A | L | V | N | H | E | F | E | R | V | F | Y | K | N | N | M | A | A | G | V | T | I | F | N | I | Y | M | T | F | G | G | T | N | W | G | N | L | G | H | P | G |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
| T | T | S |
|
|  |  |  |  |  |  | S | S |
|
|
|
| T | T | S |
|
|  |  |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |  |  |  |
|
| B |
|
| T | T |
| B |
| T | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
278 | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . |
  |
  |   |
557 | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | |
. | 580 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | Q | G | I | L | R | V | G | G | N | K | K | G | I | F | T | R | D | R | K | P | K | . |
S | A | A | F | L | L | Q | K | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |
|
| . |   |
|   |
|   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|
|
|
|   |
| . | . | . | . |
|
|   |
|   |
|   |
|   |
|   |
|
|   |   |
|
|   |
|
Template Sequence |   |
G | Y | T | S | Y | D | Y | G | A | . |
. |
. |
. |
S | I | R | E | D | R | R | I | D | R | E | K | Y | S | E | L | K | L | Q |
Template Known Secondary structure |   |
S |
| S | B |
|
| T | T |
| . | . | . | . | S | B |
| T | T |
|
|
|
| S |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
358 | . | 360 | . | . | . | . | . | . | |
|
|
|
. | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . |
  |