|   |
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | |
. | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | E | I | K | K | L | D | G | L | W | A | F | S | L | D | R | E | N | C | G | I | D | Q | R | W | W | E | S | A | L | Q | E | S | R | A | I | A | V | P | G | S | F | N | D | Q | F | A | D | A | . |
D | I | R | N | Y | A | G | N | V | W | Y | Q | R | E | V | F | I | P | K | G | W | A | G | Q | R | I | V | L | R | F |
Query Conservation |   |
|   |   |   |   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |
|
|   |   |
|   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|   |
|   |
|
|   |   |   |   |
|
|   |
|   |
|   |
|
Template Sequence |   |
R | Q | D | I | L | L | N | N | N | W | N | F | R | F | S | H | Q | V | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | D | T | R | R | V | D | L | P | H | T | W | N | A | Q | D | A | L | A | G | K | I | D | Y | K | R | G | I | G | N | Y | E | K | A | L | Y | I | R | P | E | W | K | G | K | R | L | F | L | R | F |
Template Known Secondary structure |   |
|  |  |  |  |
|
| S |
|  |  |  |  |  | T | T | S | T | T | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |
| S | S |
|
| T | T | T | T | T | G | G | G | T |
| T | T |
|
|
| S |  |  |  |  |  |  |  |  |  |
|
| G | G | G | T | T | S |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
38 | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . |
  |
  |   |
89 | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | A | V | T | H | Y | G | K | V | W | V | N | N | Q | E | V | M | E | H | Q | G | G | Y | T | P | F | E | A | D | V | T | P | Y | V | I | A | G | K | S | V | R | I | T | V | C | V | N | N | E | L | N | W | Q | T | I | P | P | G | M | V | I | T | D | E | N | G | K | K | K | Q | S | Y | F | H | D | F | F | N | Y | A |
Query Conservation |   |
  |
|
|   |   |   |
|   |
|   |
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |
|   |   |
|   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |   |
|   |
|   |
|
|
|   |   |
|
|   |
|   |   |
|
|   |   |
|   |   |
|
|
|   |   |
|   |   |
|   |   |
|   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
Template Sequence |   |
D | G | V | N | S | I | A | D | V | F | I | N | R | K | H | I | G | E | H | R | G | G | Y | G | A | F | I | F | E | I | T | D | L | V | K | Y | G | E | K | N | S | V | L | V | R | A | N | N | G | E | Q | L | D | I | M | P | L | V | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | F | N | F | Y | G |
Template Known Secondary structure |   |
S |
|
| B | S |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |
| S | S | S |
|  |  |  |  |
| T | T | T | S |
| T | T | S |  |  |  |  |  |  |  |  |  |
|
|
|
| S | S | S | S |
| S | S |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S | S |
|
|
|
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
107 | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 170 | . |
  |
  |   |
169 | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | 190 | . | |
. | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | |
|
|
. | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  | . | . | . | . | . | . | . |  |  |  |  |  | . |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
G | I | H | R | S | V | M | L | Y | T | T | P | N | T | W | V | D | D | . |
. |
. |
. |
. |
. |
. |
I | T | V | V | T | . |
H | V | A | Q | D | C | N | H | A | S | V | D | W | Q | V | V | A | N | G | . |
. |
. |
D | V | S | V | E | L | R | D | A | D | Q | Q | V | V | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|
|   |
|   |
|   |
|   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . |   |   |
|   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|   |
|   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | I | Y | R | D | V | H | L | L | I | T | D | E | T | C | I | S | P | L | D | Y | A | S | P | G | V | Y | L | V | Q | E | V | V | S | P | Q | E | A | K | V | C | A | K | V | N | L | S | N | R | A | A | D | G | T | A | E | L | Q | V | L | V | T | D | G | T | K | V | I | C | K | E | S | R | N | V | S | L | K | Q | G |
Template Known Secondary structure |   |
B |
|
| S |
|  |  |  |  |  |  |
| S |  |  |  |
| S |
| S | T | T | S |
| S |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | S |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
172 | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . |
  |
  |   |
226 | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | |
. | . | . | . | . | 250 | . | . | . | . | . | . | |
. | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | |
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  | . |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
| . |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | G | Q | G | T | S | G | T | L | Q | V | V | N | P | H | L | W | Q | P | . |
G | E | G | Y | L | Y | E | L | C | V | T | A | . |
K | S | Q | T | E | C | D | I | Y | P | L | R | V | G | I | R | S | V | A | V | K | G | E | . |
Q | F | L | I | N | H | K | P | F | Y | F | T | G | F | G | R | H | E | D | A | D | L | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|   |
| . |   |   |
|   |
|
|   |   |   |   |   |
| . |   |   |
|   |   |   |
|   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   | . |   |
|   |
|
|
|
|
|   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|
|   |   |   |
|   |
|
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |
|
|   |
|
|
|
|   |
|   |
|
|
|   |   |   |
|   |
|   |   |   |   |
Template Sequence |   |
A | D | I | L | E | Q | L | P | L | L | I | Q | K | P | R | L | W | N | G | C | E | D | P | F | M | Y | Q | V | S | I | S | L | H | K | D | G | K | Q | I | D | S | V | T | Q | P | L | G | L | R | Y | Y | H | T | D | P | D | K | G | F | F | L | N | G | K | H | L | P | L | H | G | V | C | R | H | Q | D | R | A | E | V |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  | S |
|
|
| B |
| G | G | G |
| B |
|
|  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | T | T | T |  |  |  |  | T | T |  |  |
|
|
|  |  |  |  |
|
| S |
| B | T | T | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
252 | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . |
  |
  |   |
303 | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | K | G | F | D | N | V | L | M | V | H | D | H | A | L | M | D | W | I | G | A | N | S | Y | R | T | S | H | Y | P | Y | A | E | E | M | L | D | W | A | D | E | H | G | I | V | V | I | D | E | T | A | A | V | G | F | N | L | S | L | G | I | G | F | E | A | G | N | K | P | K | E | L | Y | S | E | E | A | V | N | G |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
Template Conservation |   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|   |
|
|   |   |
|   |
|   |   |   |   |   |   |
|   |
|
|
|   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
Template Sequence |   |
G | N | A | L | R | P | Q | H | H | E | E | D | V | A | L | M | R | E | M | G | V | N | A | I | R | L | A | H | Y | P | Q | A | T | Y | M | Y | D | L | M | D | K | H | G | I | V | T | W | A | E | I | P | F | V | G | P | G | G | Y | A | D | K | G | F | V | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | A |
Template Known Secondary structure |   |
B | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  | T | T | S |
|
|
|  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |
|
|
| B |
|
| T | T | S | S | S |
| S |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | S |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
332 | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . |
  |
  |   |
383 | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | T | Q | Q | A | H | L | Q | A | I | K | E | L | I | A | R | D | K | N | H | P | S | V | V | M | W | S | I | A | N | E | P | D | T | R | P | Q | G | A | R | E | Y | F | A | P | L | A | E | A | T | R | K | L | D | P | T | R | P | I | T | C | V | N | V | M | F | C | D | A | H | T | D | T | I | S | D | L | F | D | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|
|
|
|
|   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|
|
|
|
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|
|
|
|
|   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
S | F | R | E | N | G | K | Q | Q | L | I | E | L | I | R | Q | H | Y | N | H | P | S | I | C | F | W | G | L | F | N | E | L | K | E | V | G | D | N | P | V | E | Y | V | K | E | L | N | A | L | A | K | Q | E | D | P | T | R | P | T | T | S | A | S | N | Q | D | . |
. |
. |
. |
. |
G | N | L | N | F | I | T | E | N |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| T | T |  |  |  |  |  |  |  |  | S |
|
| S | S | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |
|
|
| . | . | . | . | . | S | G | G | G | G | S | S | S | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
399 | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 470 | . | . | . |
  |
  |   |
463 | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | C | L | N | R | Y | Y | G | W | Y | V | Q | S | G | D | L | E | T | A | E | K | V | L | E | K | E | L | L | A | W | Q | E | K | L | H | Q | P | I | I | I | T | E | Y | G | V | D | T | L | A | G | L | H | S | M | Y | T | D | M | . |
. |
. |
. |
. |
. |
. |
W | S | E | E | Y | Q | C | A | W | L | D | M | Y | H | R |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |
|   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . | . | . |   |
|   |   |
|   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | A | W | N | R | Y | D | G | W | Y | G | . |
. |
S | T | P | K | T | L | A | T | F | L | D | R | T | H | K | K | . |
. |
. |
H | P | E | L | R | I | G | I | S | E | Y | G | A | G | A | S | I | Y | H | Q | Q | D | S | L | K | Q | P | S | A | S | G | W | W | H | P | E | N | W | Q | T | Y | Y | H | M | E | N | W | K |
Template Known Secondary structure |   |
 |  |  |  |
|
| T | T | T | S | S | . | . | S |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |
| T | T |
|
|  |  |  |  |  |  |
|
|
|
| B | T | T |
|
|
| S | S |
|
|
|
|
| T | T | S | S |
|
| B |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
474 | . | . | . | . | . | 480 | . | . | . | . | |
|
. | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | |
|
|
. | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . |
  |
  |   |
536 | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | |
|
. | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | |
. | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | F | D | R | V | S | A | V | V | G | E | Q | V | W | N | F | A | D | F | A | T | S | Q | G | I | . |
. |
L | R | V | G | G | N | K | K | G | I | F | T | R | D | R | K | . |
P | K | S | A | A | F | L | L | Q | K | R | W | T | G |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   | . |
|
|   |
|   |
|   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |   |
|   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |
|   |   |   |   |
|
|   |   |
|
|   |
|   |
|   |
|   |   |
Template Sequence |   |
I | I | A | E | R | P | F | V | W | G | T | F | V | W | N | M | F | D | F | G | A | A | H | R | T | E | G | D | R | P | G | I | N | D | K | G | L | V | T | F | D | R | K | V | R | K | D | A | F | Y | F | Y | K | A | N | W | N | K |
Template Known Secondary structure |   |
 |  |  | T |
| T | T |
|
|
|  |  |  | S |
| S | B |
|  |  |
| T | T |
|
|
| T | T | S | T | T |  |  |
|
|
| S | B |
| T | T | S |
|
| B |
|  |  |  |  |  |  |  |  |  |  |
| T |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
549 | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . |
  |