|   |
271 | . | . | . | . | . | . | . | . | 280 | . | . | |
. | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|  |  |  | . |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
Query Sequence |   |
I | R | S | V | A | V | K | G | E | Q | F | L | . |
I | N | H | K | P | F | Y | F | T | G | F | G | R | H | E | D | A | D | L | R | G | K | G | F | D | N | V | L | M | V | H | D | H | A | L | M | D | W | I | G | A | N | S | Y | R | T | S | H | Y | P | Y | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |
|   | . |
|
|
|
|
|   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
  |   |   |
|   |
|   |
|   |   |
|   |
|   |
|
|   |   |   |   |
|   |
|
|
|   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |
|   |
|   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
Template Sequence |   |
Y | G | K | V | Q | V | C | G | T | Q | L | C | D | E | H | G | N | P | V | Q | L | R | G | M | S | T | H | . |
G | I | Q | W | F | D | H | C | L | T | D | S | S | L | D | . |
. |
. |
A | L | A | Y | D | W | K | A | D | I | I | R | L | S | M | Y | I | Q | E | D | G | Y | E | T | N | P | R | G | F | T | D | R | M | H |
Template Known Secondary structure |   |
 |
| S |
|  |  |  | T | T |  |  |  |
| T | T | S |
| B |
|
|
|  |  |  |  |  |
| . |
|  |  |  |  | G | G | G |
| S |  |  |  |  |  | . | . | . |  |  |  |  | T | S |
|
| S |  |  |  |  |  |  |  | S | S | T | T | S | G | G | G |
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
| . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  | . | . | . |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
132 | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | |
. | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | |
|
|
. | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . |
  |
  |   |
336 | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | M | L | D | W | A | D | E | H | G | I | V | V | I | D | E | T | A | A | V | G | F | N | L | S | L | G | I | G | F | E | A | G | N | K | P | K | E | L | Y | S | E | E | A | V | N | G | E | T | Q | Q | A | H | L | Q | A | I | K | E | L | I | A | R | D | K | N | H | P | S | V | V | M | W | S | I | A | N | E | P | D |
Query Conservation |   |
  |   |   |
|   |
|
|
|   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|
|
|
|
|   |
|   |   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|   |   |   |
|
|   |
|
|
|
|   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|   |   |
Template Sequence |   |
Q | L | I | D | M | A | T | A | R | G | L | Y | V | I | V | D | W | H | I | L | T | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | D | P | H | Y | N | L | D | R | A | K | T | F | F | A | E | I | A | Q | R | H | A | S | K | T | N | V | L | Y | E | I | A | N | E | P | N | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |  |  |
|
| S | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
| G | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| S | S |  |  |  |  |
|
| S |
|
|
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
208 | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . |
  |
  |   |
416 | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | R | P | Q | G | A | R | E | Y | F | A | P | L | A | E | A | T | R | K | L | D | P | T | R | P | I | T | C | V | N | V | M | F | C | D | A | H | T | D | T | I | S | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | F | D | V | L | C | L | N | R | Y | Y | G | W | Y | V | Q | S | G | D | L | E | T | A | E | K | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |
|   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |
Template Sequence |   |
V | S | W | A | S | I | K | S | Y | A | E | E | V | I | P | V | I | R | Q | R | D | P | D | S | V | I | I | V | G | T | R | G | W | S | S | L | G | V | S | E | G | S | G | P | A | E | I | A | A | N | P | V | N | A | S | N | I | M | Y | A | F | H | F | Y | A | A | S | H | R | . |
. |
. |
. |
. |
D | N | Y | L | N | A |
Template Known Secondary structure |   |
S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|  |  |  |  |
|
|  |  |  |  | S | T | T | G | G | G | T |
|
| T |  |  |  |  |  | S |
|
| S | S | S | S |  |  |  |  |  |  |  |  | T | T | T |
|
| . | . | . | . | . |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  | . | . | . | . | . |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
267 | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 340 | . |
  |
  |   |
485 | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | E | K | E | L | L | A | W | Q | E | K | L | H | Q | P | I | I | I | T | E | Y | G | V | D | T | L | A | G | L | H | S | M | Y | T | D | M | W | S | E | E | Y | Q | C | A | W | L | D | M | Y | H | R | V | F | D | R | V | S | A | V | V | G | E | Q | V | W | N | F | A | D | F | A | T | S | Q | G | I | L | R | V | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   | . | . | . | . | . | . |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | R | E | A | S | E | L | . |
. |
. |
. |
. |
. |
F | P | V | F | V | T | E | F | G | T | E | T | Y | T | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
D | G | A | N | D | F | Q | M | A | D | R | Y | I | D | L | M | A | E | R | K | . |
. |
I | G | W | T | K | W | N | Y | S | D | D | F | R | S | G | A | V | F | Q | P | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | . | . | . | . | . | . | S |
|  |  |  |  |  |  |  | S | S |
| T | T | S | . | . | . | . | . | . | . | . | . |
| S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . |
|  |  |  |  |  |  |  | S |
|
| S | S | T | T | S | S | B |
| T | T |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
| . | . | . | . | . | . |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
342 | . | . | . | . | . | . | |
|
|
|
|
|
. | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | |
|
. | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . |
  |
  |   |
565 | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 |
Predicted Secondary structure |   |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | N | K | K | G | I | F | T | R | D | R | K | P | K | S | A | A | F | L | L | Q | K | R | W | T | G |
Query Conservation |   |
  |   |   |   |
|
|
|
|   |
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | C | A | S | G | G | P | W | S | G | S | S | L | K | A | S | G | Q | W | V | R | S | K | L | Q | S |
Template Known Secondary structure |   |
T | T | T | T | T |
|
| S | S | G | G | G | B |
|  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
405 | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 |
  |