Return to main results Retrieve Phyre Job Id

Job DescriptionP0A8T7
Confidence100.00%DateWed Jan 25 15:20:19 GMT 2012
Rank5Aligned Residues1202
% Identity24%Templatec1i6hA_
PDB info PDB header:transcription/dna-rna hybridChain: A: PDB Molecule:dna-directed rna polymerase ii largest subunit; PDBTitle: rna polymerase ii elongation complex
Resolution3.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   910.........20.........30.........40.........50.........60.........70.........80........
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Query Sequence  KAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKC
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Template Conservation   
      
  
 
   
  

   
  

            
   

 
  
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Template Sequence  YSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRL. . . . . . . . . . . . . . . GSIDRNLKCQTC
Template Known Secondary structure 

SS





















S
BTTBSS

SSSS
SSS...............

STT


STT
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   6...10.........20.........30.........40.........50........ .60.........70
 
   8990.........100.........110.........120.........130.........140.........150.........160........
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Query Sequence  GVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDA
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Template Sequence  QEGMNECP. . . GHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMV
Template Known Secondary structure 


SSS

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GGGTTTTTTS

TTSTTTS


SSS

B
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   71....... .80.........90.........100.........110.........120.........130.........140.......
 
   169170.........180.........190.........200.........210.........220.........230.........240........
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Query Sequence  LEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPD
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Template Sequence  CETDVPSLVSRGGCGNTQPTIRKDGLKLVGSWKLRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPP
Template Known Secondary structure 

S



S



B

TT



T

TT

SSS

GGGS

TT
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   148.150.........160.........170.........180.........190.........200.........210.........220.......
 
   249250.........260.........270.........280.........290.........300.........310.........320........
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Query Sequence  LRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLA
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Template Sequence  VRPS. . . . . . . . . EDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQP. . . . . QAPVKSIR
Template Known Secondary structure  TS

.........

S


STTSTT
SSSSS

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S
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   246... 250.........260.........270.........280.........290.........300... ......310.
 
   329330.........340.........350.........360.........370.........380.........390.........400.......
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Query Sequence  DMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAV.
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Template Sequence  ARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVI
Template Known Secondary structure  SSSSSTTSS


SS
TTS
TTS

TTT
TTSTT
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   327..330.........340.........350.........360.........370.........380.........390.........400......
 
   408.410.........420.........430.........440.........450.........460.....
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . VWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQ
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Template Sequence  RDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDE
Template Known Secondary structure 
TT


TTS
GGGS




TT


TT

SS

SSTTSSSS
GGGT

TTT
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   407..410.........420.........430.........440.........450.........460.........470.........480......
 
   466...470.........480.........490.........500.........510.... .....520.........530.........540....
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Query Sequence  MAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMT. RDCVNAKGEGMVLTGPKEAERLYRSGLASL
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Template Sequence  MNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLY. . . . . . WVPDWDGVI
Template Known Secondary structure 


SSBTGGGSB
SSSSSBS



STT
......STT

S

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   487..490.........500.........510.........520.........530.........540.........550. ........560
 
   545....550.........560.........570. ........580.........590.........600.. .......610..
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Query Sequence  HARVKVRITEYEKDANGELVAKTSLKD. . . . . . . . TTVGRAILWMIVPKGLPYSIVNQALGKKAIS. . . . KMLNTCYRIL
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Template Sequence  P. . . TPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREK
Template Known Secondary structure 
...

S

SSS
S
TT




TT

SS
TTS
S
TTS

SSS
SS
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   561 ........570.........580.........590.........600.........610.........620.........630.......
 
   613......620.........630.........640......... 650.........660.........670.........680........
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Query Sequence  GLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEK. . . . KHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAA
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Template Sequence  GPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLR. . . . . .
Template Known Secondary structure 
TT




GGGG


TT




TTS
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   638.640.........650.........660.........670.........680.........690.........700.........710.
 
   689690.........700.........710.........720.........730.........740.........750........
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Query Sequence  ANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETP. . . . . . . . . .
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Template Sequence  . . ESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSK
Template Known Secondary structure  ..S
TT
TTTSS

S



BTTBS


SBTTBSSTTS
S
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   712.......720.........730.........740.........750.........760.........770.........780.........
 
   759760.........770.........780.........790.........800.........810.........820........
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Query Sequence  . . . . . . . . . . ITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEG
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Template Sequence  DDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYG
Template Known Secondary structure  S

STTTTT
S
TTT


TT

TTS

TT

SSGG
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   790.........800.........810.........820.........830.........840.........850.........860.........
 
   829830...... ...840.........850.
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Query Sequence  GDVKEPLR. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DRVLGRVTAEDVLKP
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Template Conservation   



                                                                           
Template Sequence  EDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVD
Template Known Secondary structure  GTTB
GGG
TTSSS



SS
TTSS

TTTSSSSTTTTT

TT
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   870.........880.........890.........900.........910.........920.........930.........940.........
 
   852.......860... ......870........
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Query Sequence  GTADILVPRNTL. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . LHEQWCDLLEENSVD
Query Conservation       
   
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Template Conservation                
                                                             
  
Template Sequence  GEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATR
Template Known Secondary structure 


S
TTTT

TTS




TTS

S



STTS
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   950.........960.........970.........980.........990.........1000.........1010.........1020.........
 
   879880.........890.........900.........910.........920.........930.........940.........950........
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Query Sequence  AVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSI
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Template Sequence  RVLQEYRLTKQAFDWVLSNIEAQ. . FLRSVVHPGEMVGVLAAQSIGEPATQMTLKKVT. . . . . . . . . . . . . . . . . . . . . S
Template Known Secondary structure  TS


..B

TT

TTTTT




S
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   1030.........1040.........1050.. .......1060.........1070.........1080..... .
 
   959960.........970.........980.........990.........1000.........1010.........1020.........1030........
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Query Sequence  KLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFT
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Template Sequence  GVPRLKEILNVAKNMKTPSLTVYLE. . PGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHF
Template Known Secondary structure  T
SS
SS

B
..SS
SS
S
SGGG


TTS
SSGGGTSS
Template Predicted Secondary structure 






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   1097..1100.........1110.........1120. ........1130.........1140.........1150.........1160.........1170....
 
   10391040.........1050.........1060.........1070.... .....1080.........1090.........1100.........1110.......
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Query Sequence  DMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDL. RPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISS
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Template Sequence  SLQQ. . . . . . . . . . . SPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLI. . . . . . . . IRCRVVAE
Template Known Secondary structure 



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S
TT

TTS
SSS

TTSSS
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   1175... .1180.........1190.........1200.........1210.........1220....... ..1230.....
 
   1118.1120.........1130.........1140.........1150.........1160.........1170.........1180.........1190.......
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Query Sequence  GDTLARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLN
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Template Sequence  EDHMLKKIENTMLENITLRGVENIERVVMMK. . . . . . . . . . . . . . . . . . . . . . . YDRKVPSPTGEYVKEPEWVLETDGVN
Template Known Secondary structure 
TT
S
TT

.......................


TTSS

S

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   1256...1260.........1270.........1280...... ...1290.........1300.........1310..
 
   1198.1200.........1210.........1220.........1230.........1240.........1250.........1260.........1270.......
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Query Sequence  VFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEG
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Template Sequence  LSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGL. . . . . . . . . . .
Template Known Secondary structure  TTSSSB
TTT
S

TTS



TTSS
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   1313......1320.........1330.........1340.........1350.........1360.........1370.........1380.
 
   1278.1280.........1290.........1300.........1310..... ....1320.........1330.........1340.........1350.....
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Query Sequence  EQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLA. . TESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGR
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQ
Template Known Secondary structure  .............................

SSTTSS

TTT
TT

S
STT
Template Predicted Secondary structure  .............................














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   1382.......1390.........1400.........1410.........1420.........1430..
 
   1356...1360......
Predicted Secondary structure 






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Query Sequence  LIPAGTGYAYH
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Template Conservation   
  


 


Template Sequence  MAPIGTGAFDV
Template Known Secondary structure 

SSGGGSS

Template Predicted Secondary structure 






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   1433......1440...
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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