Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	Q	S	R	N	D	H	L	R	Q	T	A	L	R	N	A	H	T	P	A	L	L	L	T	T	L	T	E	P	Q	D	R	S	L	A	I	N	N	P	Q	L	A	A	D	V	K	T	A	W	L	K	E	D	P	S	L	L	L	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?									?										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.
Sequence		V	E	Q	P	D	L	S	L	L	R	D	L	V	K	T	G	A	T	R	K	I	R	S	E	A	R	H	R	L	E	E	K	Q
Secondary structure
SS confidence
Disorder																		?	?													?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1sg5 chain A domain 1 Region: 32 - 42 Aligned: 11 Modelled: 11 Confidence: 24.5% Identity: 18% Fold: Rof/RNase P subunit-like Superfamily: Rof/RNase P subunit-like Family: Rof-like Phyre2 PDB 1h3g chain A domain 1 Region: 28 - 42 Aligned: 15 Modelled: 14 Confidence: 12.3% Identity: 20% Fold: Immunoglobulin-like beta-sandwich Superfamily: E set domains Family: E-set domains of sugar-utilizing enzymes Phyre2 PDB 3af5 chain A Region: 53 - 79 Aligned: 27 Modelled: 27 Confidence: 9.1% Identity: 37% PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein ph1404; PDBTitle: the crystal structure of an archaeal cpsf subunit, ph1404 from2 pyrococcus horikoshii Phyre2 PDB 2a93 chain A Region: 79 - 90 Aligned: 12 Modelled: 12 Confidence: 6.8% Identity: 50% PDB header:leucine zippers Chain: A: PDB Molecule:c-myc-max heterodimeric leucine zipper; PDBTitle: nmr solution structure of the c-myc-max heterodimeric2 leucine zipper, 40 structures Phyre2 PDB 1a93 chain A Region: 79 - 90 Aligned: 12 Modelled: 12 Confidence: 6.8% Identity: 50% PDB header:leucine zipper Chain: A: PDB Molecule:myc proto-oncogene protein; PDBTitle: nmr solution structure of the c-myc-max heterodimeric2 leucine zipper, nmr, minimized average structure Phyre2 PDB 2h80 chain A domain 1 Region: 41 - 58 Aligned: 16 Modelled: 18 Confidence: 6.0% Identity: 25% Fold: SAM domain-like Superfamily: SAM/Pointed domain Family: Variant SAM domain Phyre2 PDB 2oa5 chain A domain 1 Region: 70 - 92 Aligned: 23 Modelled: 23 Confidence: 5.9% Identity: 22% Fold: BLRF2-like Superfamily: BLRF2-like Family: BLRF2-like Phyre2 1 d1sg5a1 2 d1h3ga1 3 c3af5A_ 4 c2a93A_ 5 c1a93A_ 6 d2h80a1 7 d2oa5a1

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1sg5a1 24.5 18 Fold:Rof/RNase P subunit-like Superfamily:Rof/RNase P subunit-like Family:Rof-like 2 d1h3ga1 12.3 20 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:E-set domains of sugar-utilizing enzymes 3 c3af5A_ 9.1 37 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein ph1404; PDBTitle: the crystal structure of an archaeal cpsf subunit, ph1404 from2 pyrococcus horikoshii 4 c2a93A_ 6.8 50 PDB header:leucine zippers Chain: A: PDB Molecule:c-myc-max heterodimeric leucine zipper; PDBTitle: nmr solution structure of the c-myc-max heterodimeric2 leucine zipper, 40 structures 5 c1a93A_ 6.8 50 PDB header:leucine zipper Chain: A: PDB Molecule:myc proto-oncogene protein; PDBTitle: nmr solution structure of the c-myc-max heterodimeric2 leucine zipper, nmr, minimized average structure 6 d2h80a1 6.0 25 Fold:SAM domain-like Superfamily:SAM/Pointed domain Family:Variant SAM domain 7 d2oa5a1 5.9 22 Fold:BLRF2-like Superfamily:BLRF2-like Family:BLRF2-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0