|   |
15 | . | . | . | . | 20 | . | . | . | |
|
|
|
|
. | . | . | . | . | |
|
|
. | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|  |  |  |
|
| . | . | . | . | . |
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | P | N | P | F | C | L | S | S | . |
. |
. |
. |
. |
S | P | V | G | N | . |
. |
. |
C | Y | E | M | C | A | K | A | Y | D | T | G | W | G | G | V | V | F | K | T | I | G | F | F | I | A | N | E | V | S | P | R | F | D | H | L | V | K | E | D | T | G | F | I | G | F | K | N | M | E | Q | I | A | E | H | P | L | E |
Query Conservation |   |
|   |
|
|
|   |   |
|
| . | . | . | . | . |
|   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|
|
|   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
L | P | H | G | L | I | V | S | C | Q | A | L | P | D | E | P | L | H | S | S | F | I | X | S | K | X | A | L | A | A | Y | E | G | G | A | V | G | I | R | A | N | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
S |
| S |  |  |  |  |  |
|
|
|
| T | T | S | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |  | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
87 | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | |
|
|
|
|
|
. | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | N | L | A | A | L | R | R | L | K | E | D | Y | P | D | K | V | L | I | A | S | I | M | G | E | N | E | Q | Q | . |
. |
. |
. |
. |
. |
W | E | E | L | A | R | L | V | Q | E | A | G | A | D | M | I | E | C | N | F | S | C | P | Q | M | T | S | H | A | M | G | S | D | V | G | Q | S | P | E | L | V | E | K | Y | C |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . |   |   |   |
|   |   |   |
|   |   |   | . |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
. |
. |
K | E | D | I | L | A | I | K | E | T | V | . |
D | L | P | V | I | G | I | V | K | R | D | Y | D | H | S | D | V | F | I | T | A | T | S | K | E | V | D | E | L | I | E | S | Q | C | E | V | I | A | L | D | A | T | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | Q | R | P | K | E | T | L | D | E | L | V |
Template Known Secondary structure |   |
. | . |  |  |  |  |  |  |  |  |  |  |
| . |
| S |
|  |  |  |  |
| B |
|
|
| T | T |
|
|
|
| B | S |
| S |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |  |
| S |
| . | . | . | . | . | . | . | . | . | . | . | S |
|
| S | S | S |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
44 | . | . | . | . | . | 50 | . | . | . | . | |
. | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | 100 | . | . | . | . | . | . | . | . | . |
  |
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | A | V | K | R | G | S | T | L | P | M | L | A | K | M | T | P | N | I | G | D | M | C | E | V | A | L | A | A | K | R | G | G | A | D | G | I | A | A | I | N | T | V | K | S | I | T | N | I | D | L | N | Q | K | I | G | M | P | I | V | N | G | K | S | S | I | S | G | Y | S | G | K | A | V | K | P | I | A | L | R |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|
|
|
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |
|   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |
|   |   |
| . | . | . | . |
|   |   |
|   |   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
Template Sequence |   |
S | Y | I | R | T | H | A | P | N | V | E | I | X | A | D | I | A | T | V | E | E | . |
. |
. |
. |
A | K | N | A | A | R | L | G | F | D | Y | I | G | T | T | L | H | G | Y | T | S | Y | T | Q | G | Q | L | L | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | N | D | F | Q |
Template Known Secondary structure |   |
 |  |  |  |  |  |
| T | T | S |  |  |  |  |  |
| S | S |  |  |  | . | . | . | . |  |  |  |  |  |  | T | T |
| S |  |  |  |
| T | T | T | T | S | S | T | T | S | T | T |
|
| T | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  | . | . | . | . |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | |
|
|
|
. | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
160 | . | . | . | . |
  |
  |   |
241 | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | I | Q | Q | M | R | T | H | P | E | L | R | D | F | P | I | S | G | I | G | G | I | E | T | W | E | D | A | A | E | F | L | L | L | G | A | A | T | L | Q | V | T | T | G | I | M | Q | Y | G | Y | R | I | V | E | D | M | A | S | G | L |
Query Conservation |   |
  |
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|
|
|   |   |   |   |
|
|   |   |   |
|   |
|
|
|   |   |
|
|
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   |   |   | . | . | . |   |   |
|
|
|
|
|   |
|
|
|   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |
|
|   |
|
|
|
|
|   | . | . |   |
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
F | L | K | D | V | L | Q | S | . |
. |
. |
V | D | A | K | V | I | A | E | G | N | V | I | T | P | D | X | Y | K | R | V | X | D | L | G | V | H | C | S | V | V | G | G | A | I | T | . |
. |
R | P | K | E | I | T | K | R | F | V | Q | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | . | . | . |
|
| S |  |  |  |  |  | S | S |
|
| S |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |
|  |  |  |  | . | . |
|  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  | . | . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
165 | . | . | . | . | 170 | . | . | |
|
|
. | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | |
|
. | . | 210 | . | . | . | . | . | . | . | . | . |
  |