|   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | |
|
. | . | . | 20 | . | . | . | . | . | . | . | |
|
. | . | 30 | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|  |  |  |
| . | . |
|
|  |  |  |
|
|
|
|
|
| . | . |
|
|  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | D | L | S | I | T | F | C | G | V | K | F | P | . |
. |
N | P | F | C | L | S | S | S | P | V | G | . |
. |
N | C | Y | . |
. |
. |
. |
. |
. |
. |
E | M | C | A | K | A | Y | D | T | G | W | G | G | V | V | F | K | T | I | G | F | F | I | A | N | E | V | S | P | R | F | D | H | L | V | K | E | D | T | G | F | I |
Query Conservation |   |
  |
|
|
|   |   |   |   |
|   |   |
|   | . | . |
|
|
|   |   |
|
|
|   |   |   | . | . |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |
|   |
|   |   |   |   |
|
|   |   |   |
|   |   |
|
|
|
|
|
|   |   |
|
|
|   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |
|
|
|   |
|
|   |
|   |   |   |   |   |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
Q | N | K | I | V | K | I | G | N | I | D | V | A | N | D | K | P | F | V | L | F | G | G | X | N | V | L | E | S | R | D | X | A | X | Q | V | C | E | A | Y | V | K | V | T | E | K | L | G | V | P | Y | V | F | K | A | S | F | D | K | A | N | R | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
|
|
|
|  |  |  | T | T |  |  |  |
| T | T | S |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  | S |
|
| T | T |
| S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
73 | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . |
Predicted Secondary structure |   |
 |  |
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | F | K | N | M | E | Q | I | A | E | H | P | L | E | E | N | L | A | A | L | R | R | L | K | E | D | Y | P | D | K | V | L | I | A | S | I | M | G | E | N | E | Q | Q | W | E | E | L | A | R | L | V | Q | E | A | G | A | D | M | I | E | C | N | F | S | C | P | Q | M | T | S | H | A | M | G | S | D | V | G | Q | S |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   | . |
|
|   |   |   |
|
|   |   |
| . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   | . |
|   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|   |   |   |   |
|
Template Sequence |   |
. |
. |
. |
S | I | H | S | Y | R | G | P | G | X | E | E | G | L | K | I | F | Q | E | L | K | D | T | F | . |
G | V | K | I | I | T | D | V | H | E | . |
. |
. |
. |
. |
. |
I | Y | Q | C | Q | P | V | A | D | V | . |
V | D | I | I | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | P | A | F | L | A | R | Q |
Template Known Secondary structure |   |
. | . | . | S | T | T | S |
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|  |  |  |  |  |
|
| S | . | . | . | . | . | . | G | G | G |  |  |  |  |  | T | T | . |
| S |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |
| G | G | G | T | T |
|
Template Predicted Secondary structure |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
65 | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | |
. | 90 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 100 | . | . | . | . | . | . | . | . | |
. | 110 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 120 | . |
  |
  |   |
153 | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | |
|
. | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | E | L | V | E | K | Y | C | R | A | V | K | R | G | S | T | L | P | M | L | A | K | M | T | P | . |
. |
N | I | G | D | M | C | E | V | A | L | A | A | K | R | G | G | A | D | G | I | A | A | I | N | T | V | K | S | I | T | N | I | D | L | N | Q | K | I | G | M | P | I | V | N | G | K | S | S | I | S | G | Y | S |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |
|
|
|   |
| . | . |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|
|
|
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
  |   |
|
|   |   |
|
|   | . | . | . | . | . |   |
|
|
|
|
|
|
|
|
|   |
|   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|   |
|   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |
|
Template Sequence |   |
T | D | L | V | E | A | X | A | K | . |
. |
. |
. |
. |
T | G | A | V | I | N | V | K | K | P | Q | F | L | S | P | S | Q | X | G | N | I | V | E | K | I | E | E | C | G | N | D | K | I | I | L | C | D | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | T | N | F |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | . | . | . | . | . | T | T |
|  |  |  |  |  |
|
| T | T | S |
| G | G | G |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
122 | . | . | . | . | . | . | . | 130 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 170 | . | . |
  |
  |   |
231 | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 290 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  | . | . | . | . | . |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | K | A | V | K | P | I | A | L | R | F | I | Q | Q | M | R | T | H | P | E | L | R | D | F | P | I | S | G | . |
. |
. |
. |
. |
I | G | G | I | E | T | W | E | D | A | A | E | F | L | L | L | G | A | A | T | L | Q | V | T | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | I | M | Q | Y | G | Y | R | I | V | E | D |
Query Conservation |   |
|   |   |
|   |
|   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|   | . | . | . | . | . |   |
|
|
|   |   |   |   |
|
|   |   |   |
|   |
|
|
|   |   |
|
|
|   |
| . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |   |   |   | . | . |   |   |   |
|
|
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |
|   |
|
|
|
|
|   |
|   |
|   |   |   |   |
|   |   |   |
|
|   |
|   |   |
|   |   |
Template Sequence |   |
G | Y | D | N | L | I | V | D | X | L | G | F | S | V | X | K | K | A | S | . |
. |
K | G | S | P | V | I | F | D | V | T | H | S | L | Q | R | A | Q | V | T | E | L | A | R | S | G | L | A | V | G | I | A | G | L | F | L | E | A | H | P | N | P | N | Q | A | K | C | D | G | P | S | A | L | P | L | S | A | L | E | G |
Template Known Secondary structure |   |
S | T | T |
|  |  |
|
| T | T |  |  |  |  |  |  |  |  | T | . | . | T | S |
|
|  |  |  |  |  |  |  |  |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  | S | S | G | G | G |
| S | S |
|
| T | T |
|  |  | G | G | G |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
173 | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | |
|
. | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 |
  |
  |   |
296 | . | . | . | 300 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
Query Sequence |   |
M | A | S | G | L | S | H | Y |
Query Conservation |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |
|
|   |
|
Template Sequence |   |
F | V | S | Q | X | K | A | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
  |   |
263 | . | . | . | . | . | . | 270 |
  |