|   |
8 | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |
|
|
|  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | T | F | C | G | V | K | F | P | N | P | F | C | L | S | S | S | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
V | G | N | C | Y | E | M | C | A | K | A | Y | D | T | G | W | G | G | V | V | F | K | T | I | G | F | F | I | A | N | E | V | S | P | R | F | D | H | L | V | K | E | D | T | G | F | I | G | F | K | N | M | E |
Query Conservation |   |
  |   |   |   |
|   |   |
|   |
|
|
|   |   |
|
|
|   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |   |
|
|   |   |   |
|
|
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |
|
| . |
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
Template Sequence |   |
C | K | M | G | K | F | E | L | C | H | R | V | V | L | A | P | L | T | R | Q | R | S | Y | G | Y | I | P | Q | P | H | A | I | L | H | Y | S | Q | R | S | T | N | G | . |
G | L | L | I | G | E | A | T | V | I | S | E | T | G | I | G | Y | K | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | P | G |
Template Known Secondary structure |   |
 |  |  | T | T |  |  |  | S |
| S |  |  |  |
|
|
|
|
|
|
|
| G | G | G | S |
|
|  |  |  |  |  |  |  |  |  | T |
|
| T | T | . |
|  |  |  |
|
|
|  |  |
| S | G | G | G |
|
| S | T | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
| B |
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | |
. | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . |
  |
  |   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
Q | I | A | E | H | P | L | E | E | N | L | A | A | L | R | R | L | K | E | D | Y | P | D | K | V | L | I | A | S | I | M | G | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |
|
|   |   |
|   |   |
|   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |
Template Sequence |   |
I | W | T | K | E | Q | V | E | A | W | K | P | I | V | D | A | V | H | A | K | G | G | I | F | F | C | Q | I | W | H | V | G | R | V | S | N | K | D | F | Q | P | N | G | E | D | P | I | S | C | T | D | R | G | L | T | P | Q | I | M | S | N | G | I | D | I | A | H | F | T | R | P | R | R | L | T | T | D | E | I | P |
Template Known Secondary structure |   |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |
|
| T | T | S | S |
| T | T | T | S | G | G | G |
|
|
|  |  | S | S | S |
|
|
|
|
|  |  |
| T | T | S | S |
|  |  |
|
|
|
|
|  |  |
|
| T | T | T |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
84 | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . |
  |
  |   |
|
112 | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | 140 | . | . | . | . | |
|
. | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | |
. | . | 170 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
| . | . |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|
|  |  |  |  |
|
|
|
Query SS confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
N | E | Q | Q | W | E | E | L | A | R | L | V | Q | E | A | G | A | D | M | I | E | C | N | F | S | C | . |
. |
. |
. |
. |
. |
. |
. |
. |
P | Q | M | T | S | H | A | . |
. |
M | G | S | D | V | G | Q | S | P | E | L | V | E | K | Y | C | R | A | V | K | R | G | S | . |
T | L | P | M | L | A | K | M | T | P | N |
Query Conservation |   |
. |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |
|   | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   | . |   |   |
|
|   |
|
|
|   |
|   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |
|   |   |
|
|   |   |
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |
|
|
|
|
|   |   |
|   |
|
|
|   |
|
|
|
|   |
|
|
|   |
|
|   |   |
|
|
|   |
|
|
|   |   |
|
|   |   |   |
|
|
|
|
|   |   |   |
Template Sequence |   |
Q | I | V | N | E | F | R | V | A | A | R | N | A | I | E | A | G | F | D | G | V | E | I | H | G | A | H | G | Y | L | I | D | Q | F | M | K | D | Q | V | N | D | R | S | D | K | Y | G | G | S | L | E | N | R | C | R | F | A | L | E | I | V | E | A | V | A | N | E | I | G | S | D | R | V | G | I | R | I | S | P | F |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |  |
| T | T | S |  |  |  |  |  |  |
| T | T | T |
|
|
|
| S | T | T | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G |  |  |  |  |  |
| T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
164 | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
179 | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | G | D | M | C | E | V | A | L | A | A | K | R | G | G | A | D | G | I | A | A | I | N | T | V | K | S | I | T | N | I | D | L | N | Q | K | I | G | M | P | I | V | N | G | K | S | S | I | S | G | Y | S | G | K | A | V | K | P | I | A | L | R | F | I | Q | Q | M | R | T |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|
|
|
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |
|   |
|
|   |   |
|   |   |
|   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
Template Sequence |   |
A | H | Y | N | E | A | G | D | T | N | P | T | A | L | G | L | Y | M | V | E | S | L | N | K | Y | D | L | A | Y | C | H | V | V | E | P | R | M | K | T | C | T | E | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | V | P | M | R | K |
Template Known Secondary structure |   |
|
| T | T | T |
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  | G | G | G |
|
| S |  |  |  |  |  |
|
| S |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
244 | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 290 | . | . |
  |
  |   |
248 | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | |
. | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | P | E | L | R | D | F | P | I | S | G | I | G | G | I | E | T | W | E | D | A | A | E | F | L | L | L | G | . |
A | A | T | L | Q | V | T | T | G | I | M | Q | Y | G | Y | R | I | V | E | D | M | A | S | G |
Query Conservation |   |
  |   |   |   |   |   |
|
|
|
|   |   |
|
|
|   |   |   |   |
|
|   |   |   |
|   |
|
| . |
|   |   |
|
|
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  | . | . | . |   |   |   |
|
|
|   |   |
|   |   | . |   |   |   |   |
|
|   |   |
|   |   |
|   |   |
|   |
|   |   |
|
|   |
|
|
| . |
|
|
|   |   |   |
|   |   |   |
|
Template Sequence |   |
A | . |
. |
. |
Y | K | G | T | F | I | V | A | G | G | Y | . |
D | R | E | D | G | N | R | A | L | I | E | D | R | A | D | L | V | A | Y | G | R | L | F | I | S | . |
N | P | D | L | P | K | R | F | E | L | N |
Template Known Secondary structure |   |
 | . | . | . |
|
| S |
|  |  |  |  | S | S |
| . |
|  |  |  |  |  |  |  |  |  | T | T | S |
| S |  |  |  |  | S |  |  |  |  |  | . |
| T | T |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 | . | . | . |
|
|
|
|  |  |  |  |
|
|
| . |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |
| . |
|
|
|  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
299 | |
|
|
300 | . | . | . | . | . | . | . | . | . | 310 | |
. | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | |
. | . | . | . | 340 | . | . | . | . | . | . |
  |