|   |
24 | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | P | V | G | N | C | Y | E | M | C | A | K | A | Y | D | T | G | W | G | G | V | V | F | K | T | I | G | F | F | I | A | N | E | V | S | P | R | F | D | H | L | V | K | E | D | T | G | F | I | G | F | K | N | M | E | Q | I | A | E | H | P | L | E | E | N | L | A | A | L | R | R | L | K | E | D | Y | P | D | K | V |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|   |
|   |
|   |
|   |   |
|
|   |
|
|   |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|   |
|
|
|   |   |
|   |   |   |   |   |
|   |   |
|
|   |
|   |   |   |   |   |
|   |   |
Template Sequence |   |
G | P | K | T | N | N | P | E | T | L | V | A | L | R | K | A | G | L | N | I | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | M | N | F | S | H | G | S | Y | E | Y | H | K | S | V | I | D | N | A | R | K | S | E | E | L | Y | P | G | R | P |
Template Known Secondary structure |   |
| T | T | T |
| S |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  | T | T | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| S |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
28 | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . |
  |
  |   |
104 | . | . | . | . | . | 110 | . | . | . | |
|
|
. | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | |
. | . | . | . | 170 | . | . | . | . | . | . | |
|
. |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|  |  |  |  |
| . | . |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
Query Sequence |   |
L | I | A | S | I | M | G | E | N | E | . |
. |
. |
Q | Q | W | E | E | L | A | R | L | V | Q | E | A | G | A | D | M | I | E | C | N | F | S | C | P | Q | M | T | S | H | A | M | G | S | D | V | G | Q | S | P | E | L | V | E | K | Y | C | R | A | V | K | R | . |
G | S | T | L | P | M | L | A | K | M | T | . |
. |
P |
Query Conservation |   |
  |
|   |
|
|   |
|   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   | . |   |   |   |   |
|
|   |
|
|
|   | . | . |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
Template Conservation |   |
|   |
|   |   |
|
|   |
|
|   |
|
|
|
|
|   |   |
|
|   |   |
|   |   |   |
|
|
|   |
|   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |
|
|   |
|
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |
|
|
|
|
|
|
|   |   |
Template Sequence |   |
L | A | I | A | L | D | T | K | G | P | A | L | S | E | K | D | K | E | D | L | R | F | G | V | K | N | G | V | H | M | V | F | A | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | I | R | T | A | N | D | V | L | T | I | R | E | V | L | G | E | Q | G | K | D | V | K | I | I | V | K | I | E | N | Q | Q |
Template Known Secondary structure |   |
| B |
|  |  |  |
|
|
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |
|
| T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T |
|
| S |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G | T | T | S |
|
|  |  |  |  |
| S |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . |
  |
  |   |
178 | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | I | G | D | M | C | E | V | A | L | A | A | K | R | G | G | A | D | G | I | A | A | I | N | T | V | K | S | I | T | N | I | D | L | N | Q | K | I | G | M | P | I | V | N | G | K | S | S | I | S | G | Y | S | G | K | A | V | K | P | I | A | L | R | F | I | Q | Q | M | R | T | H | P | E | L | R | D | F | P | I | S |
Query Conservation |   |
  |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|
|
|
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |
|   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|   |
|
|   |   |   | . | . | . | . | . |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|   |
|   |   |   |
|   |
|   |   |   |
|
|   |
|
|   |   |
|   |   |   | . | . | . |
|
|
|
|
|
Template Sequence |   |
G | V | N | N | F | D | E | I | L | K | V | . |
. |
. |
. |
. |
T | D | G | V | M | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | R | G | D | L | G | I | E | I | P | A | P | E | V | L | A | V | Q | K | K | L | I | A | K | S | N | L | A | . |
. |
. |
G | K | P | V | I |
Template Known Secondary structure |   |
 |  | T | T |  |  |  |  |  |  |  | . | . | . | . | . |
| S |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | T |
|
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . |
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
246 | . | . | . | 250 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 260 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | |
|
|
. | . | . | . | . |
  |
  |   |
258 | . | 260 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | |
|
. | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  | . | . |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | I | G | G | I | E | T | W | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | D | A | A | E | F | L | L | L | G | A | A | T | L | Q | V | T | . |
. |
T | G | I | M | Q | Y | G | Y | R | I | V | E | D | M | A | S |
Query Conservation |   |
  |   |
|
|
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |   |   |
|   |
|
|
|   |   |
|
|
|   | . | . |
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|   |
|
|
|
|   |   |   |   |   |
|
|
|
|
|
|   |
|
|   |
|
|
|   |
|
|   |
|   |
|
|
|
|   |
|
|
|   |
|   |   |
|   |   |   |
|   |   |   |   |   |
Template Sequence |   |
C | A | T | Q | M | L | E | S | M | T | Y | N | P | R | P | T | R | A | E | V | S | D | V | G | N | A | I | L | D | G | A | D | C | V | M | L | S | G | E | T | A | K | G | N | Y | P | I | N | A | V | T | T | M | A | E |
Template Known Secondary structure |   |
 |  | S | S | S | S | G | G | G | G | T |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |
|
| S |  |  |  |  | S |
| S |
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
296 | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 |
  |