|   |
8 | . | 10 | . | |
. | . | . | . | . | . | . | . | 20 | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
| . |
|  |  |  |
|
|
|  |  |  |
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |
Query SS confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | T | F | C | . |
G | V | K | F | P | N | P | F | C | L | S | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
S | P | V | G | N | C | Y | E | M | C | A | K | A | Y | D | T | G | W | G | G | V | V | F | K | T | I | G | F | F | I | A | N | E | V | S | P | R | F | D | H | L | V | K | E | D | T | G | F | I | G | F | K | N | M |
Query Conservation |   |
  |   |   |   | . |
|   |   |
|   |
|
|
|   |   |
|
| . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
|   |
|
|
|
|
|   |
|
|
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |
|
|   |
|
|   |
|
|
|
|   |
|   |   |   |
|   |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
Template Sequence |   |
I | H | L | P | N | G | I | K | I | S | N | R | F | V | L | S | P | X | T | V | N | A | S | T | K | E | G | Y | I | T | K | A | D | L | A | Y | A | A | R | R | S | N | S | A | G | X | Q | V | T | G | A | A | Y | I | E | P | Y | G | K | L | F | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | G | F |
Template Known Secondary structure |   |
 |  |
| T | T | S |
|  |  | S | S | S |  |  |  |
|
|
|
|
|
|
| S |
| T | T |
|
|
|
|  |  |  |  |  |  |  |  |  | T | T | T | S |
| S |  |  |  |  |  |  |  |  | S | S | G | G | G |
|
| S | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T |
|  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
11 | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . |
  |
  |   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
Query Sequence |   |
E | Q | I | A | E | H | P | L | E | E | N | L | A | A | L | R | R | L | K | E | D | Y | P | D | K | V | L | I | A | S | I | M | G | E | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | Q | Q | W | E | E | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   |   |
|   |   |   |
|   |
|   |   |   |
|
|   |   |
|   |   |
|   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |
|
|   |   |
|   |   |
|
Template Sequence |   |
N | I | D | H | D | A | C | I | P | G | L | T | N | X | A | S | T | X | K | Q | H | G | S | L | A | I | I | Q | L | A | H | A | G | R | F | S | N | Q | A | I | L | N | F | G | K | V | Y | G | P | S | P | X | T | L | H | S | P | I | E | H | V | V | I | A | X | S | H | E | K | I | N | S | I | I | Q | Q | Y | R | D | A |
Template Known Secondary structure |   |
 |
| S | S | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |
|
| G | G | G |
|  |  |  |  |  |  |  | S |  |  |  |  | S | S |
|  |  |  |
| S | S | S | S |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
76 | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . |
  |
  |   |
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | 140 | . | . | . | . | |
|
. | . | . | |
. | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 170 | . | . | . | . | . | . | . | |
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
| . | . |
|
|  | . |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . |
|
|
|  |  |  |  |
|
| . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
| . |
. |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
Query Sequence |   |
A | R | L | V | Q | E | A | G | A | D | M | I | E | C | N | F | S | C | . |
. |
. |
. |
. |
. |
. |
. |
. |
P | Q | M | T | S | H | A | . |
. |
M | G | S | . |
D | V | G | Q | S | P | E | L | V | E | K | Y | C | R | A | V | K | R | G | S | T | . |
. |
. |
. |
. |
. |
L | P | M | L | A | K | M | T | P | . |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |
|   | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   | . | . |   |
|   | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   | . | . | . | . | . | . |   |
|
|   |
|
|
|   |
| . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
| . | . |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
|   |
|
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|   |
|
|   |
|
|
|
|
|
|
|   |
|
|
|
|
|   |
|
|   |   |
|
|
|   |
|
|
|   |
|
|
|   |
|   |
|   |   |   |   |
|
|   |
|
|   |   |   |
|   |   |
Template Sequence |   |
T | L | R | A | I | K | A | G | F | D | G | V | E | I | S | I | A | Q | R | L | L | I | Q | T | F | F | S | T | F | S | N | R | R | T | D | H | Y | G | A | D | S | L | K | N | R | A | R | L | C | L | E | V | X | R | A | V | Q | E | V | I | D | K | E | A | P | D | N | F | I | L | G | F | R | A | T | P | E | E | T | R |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T |
| S |  |  |  |  |  |
|
| T | T | S |  |  |  |  |  |  |
| T | T | T |
|
|
|
| S | T | T | S | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T |
|  |  |  |  |  |  |
| S |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
156 | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
178 | . | 180 | . | . | . | . | . | . | . | . | . | |
190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 |
Predicted Secondary structure |   |
. | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  | . |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
N | I | G | D | M | C | E | V | A | L | A | A | . |
K | R | G | G | A | D | G | I | A | A | I | N | T | V | K | S | I | T | N | I | D | L | N | Q | K | I | G | M | P | I | V | N | G | K | S | S | I | S | G | Y | S | G | K | A | V | K | P | I | A | L | R | F | I | Q | Q | M | R | T | H | P | E |
Query Conservation |   |
. | . | . | . | . | . |   |   |   |   |   |   |   |
|
|   |   |
| . |   |   |   |
|
|
|
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |
|   |
|
|   |   |
|   |   |
|   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |
|   |
|   |   |
|
|
|   |
|   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | S | D | L | G | Y | T | I | D | E | F | N | Q | L | I | D | W | V | X | D | V | S | N | I | Q | Y | L | A | I | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | W | G | R | H | I | Y | Q | N | T | S | R | T | P | G | D | H | F | G | R | P | V | N | Q | I | V | Y | E | H | L | A |
Template Known Secondary structure |   |
T | T |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| T | T |
|
| G | G | G |
| B |
|
|
| S | S | T | T | T | T | S | B |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
236 | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . |
  |
  |   |
251 | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | R | D | F | P | I | S | G | I | G | G | I | E | T | W | E | D | A | A | E | F | L | L | L | G | A | A | T | L | Q | V | T | T | G | I | M | Q | Y | G | Y | R | I | V | E | D | M | A | S | G |
Query Conservation |   |
  |   |   |
|
|
|
|   |   |
|
|
|   |   |   |   |
|
|   |   |   |
|   |
|
|
|   |   |
|
|
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |   |   |
|
|
|
|   |   |
|   |
|   |   |
|   |   |
|
|   |   |
|   |   |   | . |
|   |
|   |   |
|
|   |   |
|
| . |
|
|   |   |   |   |
|   |   |   |
|
Template Sequence |   |
. |
G | R | I | P | L | I | A | S | G | G | I | N | S | P | E | S | A | L | D | A | L | Q | H | A | . |
D | X | V | G | X | S | S | P | F | V | T | . |
E | P | D | F | V | H | K | L | A | E | Q |
Template Known Secondary structure |   |
. | T | S | S |
|  |  |  |
| S | S |
|
| S |  |  |  |  |  |  |  | G | G | G |
| . | S |  |  |  |  | S | T |  |  |  |  | . |
| T | T |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
. |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . |
|  |  |  |  |
|
|  |  |  |
| . |
|  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
297 | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | |
. | . | . | . | . | . | . | . | . | 330 | . | |
. | . | . | . | . | . | . | . | 340 | . | . |
  |