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Job DescriptionP25889
Confidence100.00%DateThu Jan 5 11:42:42 GMT 2012
Rank5Aligned Residues310
% Identity21%Templatec2fptA_
PDB info PDB header:oxidoreductaseChain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial; PDBTitle: dual binding mode of a novel series of dhodh inhibitors
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  LTKDLSITFCGVKFPNPFCLSSSPVGNCYEMCAKAYDTGWGGVVFKTIGFFIA. NEVSPRFDHLVKEDT. . GFIGFKN. .
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Template Sequence  DSDMLEVRVLGHKFRNPVGIAAG. FDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHG
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GGG
TTSSS
TT.TTTTSS
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B

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   75....80.........90....... ..100.........110.........120.........130.........140.........150...
 
   77..80.........90.........100........ .110.........120.........130.........140.... .....150.
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Query Sequence  MEQIAEHPLEENLAALRRLKEDYPDKVLIASI. . MGENEQQWEELARLVQEAGADMIECNFSCPQMTSHA. . . MGSDVGQ
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Template Sequence  LSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPL. ADYLVVNVSSPNTAGLRSLQGKAELRR
Template Known Secondary structure  TTTT




TT
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TTSTTSGGGGS
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   154.....160.........170.........180.........190.........200..... ....210.........220.........230..
 
   152.......160.........170.........180. ........190.........200.........210.........220.........
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Query Sequence  SPELVEKYCRAVKRGSTLPMLAKMTPNIGD. . MCEVALAAKRGGADGIAAINTVKSITNIDLNQKIGMPIVNGKSSISGY
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Template Sequence  LLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSR. . . . . . . . PAGLQGALRSETGGL
Template Known Secondary structure  TS
GGG


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   233......240.........250.........260.........270.........280......... 290.........300....
 
   230.........240.........250.........260.........270.........280.........290.........300.........
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Query Sequence  SGKAVKPIALRFIQQMRTHPELRDFPISGIGGIETWEDAAEFLLLGAATLQVTTGIMQYGYRIVEDMASGLSHYLADQGF
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Template Sequence  SGKPLRDLSTQTIREMYALTQ. GRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGF
Template Known Secondary structure  TT.T
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   305....310.........320..... ....330.........340.........350.........360.........370.........380...
 
   310.........320..
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Query Sequence  DSLQEMVGLANNN
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Template Sequence  GGVTDAIGADHRR
Template Known Secondary structure  SSTT
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   384.....390......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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