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Job DescriptionP25889
Confidence100.00%DateThu Jan 5 11:42:42 GMT 2012
Rank1Aligned Residues390
% Identity37%Templatec1gthD_
PDB info PDB header:oxidoreductaseChain: D: PDB Molecule:dihydropyrimidine dehydrogenase; PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil
Resolution2.25 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   5....10.........20.........30.........40.........50.. .......60.........70.. ......
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Query Sequence  DLSITFCGVKFPNPFCLSSSPVGNCYEMCAKAYDTGWGGVVFKTIGFF. . IANEVSPRFDHLVKEDTGFI. . . . GFKNME
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Template Sequence  DISVEMAGLKFINPFGLASAAPTTSSSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIVRGTTSGPMYGPGQSSFLNIE
Template Known Secondary structure 


TTSSS
SSGGGSST
S


B

GGG




SS


TT
S

SS

S


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   532.......540.........550.........560.........570.........580.........590.........600.........610.
 
   7980.........90.........100.........110 .........120.........130......... 140.........150......
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Query Sequence  QIAEHPLEENLAALRRLKEDYPDKVLIASIMG. ENEQQWEELARLVQEAGADMIECNFSCPQ. MTSHAMGSDVGQSPELV
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Template Sequence  LISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWMELSRKAEASGADALELNLSCPHGMGERGMGLACGQDPELV
Template Known Secondary structure 
S
SS

TTS


S
TT
S



SSGGGGT
T
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   612.......620.........630.........640.........650.........660.........670.........680.........690.
 
   157..160.........170.........180.........190.........200.........210..... ....220.........230.....
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Query Sequence  EKYCRAVKRGSTLPMLAKMTPNIGDMCEVALAAKRGGADGIAAINTVKSITNIDLNQKI. GMPIVNGKSSISGYSGKAVK
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Template Sequence  RNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGADGVTATNTVSGLMGLKADGTPWPAVGAGKRTTYGGVSGTAIR
Template Known Secondary structure 
SS

S
SS
T
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B
TTS
BSS
BTTTTB


SGGG
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   692.......700.........710.........720.........730.........740.........750.........760.........770.
 
   236...240.........250.........260.........270.........280.........290.........300....
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Query Sequence  PIALRFIQQMRTHPELRDFPISGIGGIETWEDAAEFLLLGAATLQVTTGIMQYGYRIVEDMASGLSHYL. . . . . . . . . . .
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Template Sequence  PIALRAVTTIARAL. . PGFPILATGGIDSAESGLQFLHSGASVLQVCSAVQNQDFTVIQDYCTGLKALLYLKSIEELQGW
Template Known Secondary structure  S..TT

SS

STT
SSTS
TTTT
GGGTTS
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   772.......780..... ....790.........800.........810.........820.........830.........840.........
 
   305....310.........320
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ADQGFDSLQEMVGLAN
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Template Sequence  DGQSPGTESHQKGKPVPRIAELMGKKLPNFGPYLEQRKKIIAEEKMRLKEQNAAFPPLERKPFIPKKPIPAIKDVIGKAL
Template Known Secondary structure  BTTB




TT



TTTTTS


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TTTTG
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   850.........860.........870.........880.........890.........900.........910.........920.........
 
   321........330.........340.........350.........360.........370.........380.........390 .......
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Query Sequence  NNIVPAEDLDRSYIVYPRINLDKCVGCGRCYISCYDGGHQAMEWSEKTRTPHCNTEKCVGCLLCGHVCPV. GCIELGE
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Template Sequence  QYLGTFGELSNIEQVVAVIDEEMCINCGKCYMTCNDSGYQAIQFDP. ETHLPTVTDTCTGCTLCLSVCPIIDCIRMVS
Template Known Secondary structure  GG


GGGS
SSS

TTT




S
S

T.TT


TT





SSTTS
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   930.........940.........950.........960.........970..... ....980.........990.........1000......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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