Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP37746
DateThu Jan 5 11:57:22 GMT 2012
Unique Job ID66a21274a882a1c0

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3mkuA_
Top template information
PDB header:transport protein
Chain: A: PDB Molecule:multi antimicrobial extrusion protein (na(+)/drug
PDBTitle: structure of a cation-bound multidrug and toxin compound extrusion2 (mate) transporter
Confidence and coverage
Confidence:100.0% Coverage: 98%
406 residues ( 98% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MNTNKLSLRRNVIYLAVVQGSNYLLPLLTFPYLVRTLGPENFGIFGFCQATMLYMIMFVE
Secondary structure 



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   .........70.........80.........90.........100.........110.........120
Sequence  YGFNLTATQSIAKAADSKDKVTSIFWAVIFSKIVLIVITLIFLTSMTLLVPEYNKHAVII
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   .........130.........140.........150.........160.........170.........180
Sequence  WSFVPALVGNLIYPIWLFQGKEKMKWLTLSSILSRLAIIPLTFIFVNTKSDIAIAGFIQS
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   .........190.........200.........210.........220.........230.........240
Sequence  SANLVAGIIALAIVVHEGWIGKVTLSLHNVRRSLADGFHVFISTSAISLYSTGIVIILGF
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   .........250.........260.........270.........280.........290.........300
Sequence  ISGPTSVGNFNAANTIRNALQGLLNPITQAIYPRISSTLVLNRVKGVILIKKSLTCLSLI
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   .........310.........320.........330.........340.........350.........360
Sequence  GGAFSLILLLGASILVKISIGPGYDNAVIVLMIISPLPFLISLSNVYGIQVMLTHNYKKE
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   .........370.........380.........390.........400.........410.....
Sequence  FSKILIAAGLLSLLLIFPLTTLFKEIGAAITLLATECLVTSLMLMFVRNNKLLVC
Secondary structure 





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??
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3mku chain A

3D model

Region: 2 - 411
Aligned: 406
Modelled: 406
Confidence: 100.0%
Identity: 13%
PDB header:transport protein
Chain: A: PDB Molecule:multi antimicrobial extrusion protein (na(+)/drug
PDBTitle: structure of a cation-bound multidrug and toxin compound extrusion2 (mate) transporter

Phyre2

PDB 2iub chain A domain 2

3D model

Region: 357 - 411
Aligned: 50
Modelled: 55
Confidence: 19.0%
Identity: 18%
Fold: Transmembrane helix hairpin
Superfamily: Magnesium transport protein CorA, transmembrane region
Family: Magnesium transport protein CorA, transmembrane region

Phyre2

PDB 1pv7 chain A

3D model

Region: 4 - 411
Aligned: 394
Modelled: 394
Confidence: 15.5%
Identity: 8%
Fold: MFS general substrate transporter
Superfamily: MFS general substrate transporter
Family: LacY-like proton/sugar symporter

Phyre2

PDB 1b9u chain A

3D model

Region: 391 - 410
Aligned: 20
Modelled: 20
Confidence: 8.2%
Identity: 10%
PDB header:hydrolase
Chain: A: PDB Molecule:protein (atp synthase);
PDBTitle: membrane domain of the subunit b of the e.coli atp synthase

Phyre2

PDB 2xq2 chain A

3D model

Region: 1 - 249
Aligned: 247
Modelled: 249
Confidence: 7.2%
Identity: 9%
PDB header:transport protein
Chain: A: PDB Molecule:sodium/glucose cotransporter;
PDBTitle: structure of the k294a mutant of vsglt

Phyre2
1

c3mkuA_
2

d2iuba2
3

d1pv7a_
4

c1b9uA_
5

c2xq2A_



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3mkuA_



100.0 13 PDB header:transport protein
Chain: A: PDB Molecule:multi antimicrobial extrusion protein (na(+)/drug
PDBTitle: structure of a cation-bound multidrug and toxin compound extrusion2 (mate) transporter
2d2iuba2



19.0 18 Fold:Transmembrane helix hairpin
Superfamily:Magnesium transport protein CorA, transmembrane region
Family:Magnesium transport protein CorA, transmembrane region
3d1pv7a_



15.5 8 Fold:MFS general substrate transporter
Superfamily:MFS general substrate transporter
Family:LacY-like proton/sugar symporter
4c1b9uA_



8.2 10 PDB header:hydrolase
Chain: A: PDB Molecule:protein (atp synthase);
PDBTitle: membrane domain of the subunit b of the e.coli atp synthase
5c2xq2A_



7.2 9 PDB header:transport protein
Chain: A: PDB Molecule:sodium/glucose cotransporter;
PDBTitle: structure of the k294a mutant of vsglt

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0