|   |
38 | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | S | A | L | N | N | F | L | E | P | L | L | R | K | E | N | L | R | I | I | L | T | G | A | G | T | S | A | F | I | G | D | I | I | A | P | W | L | A | S | H | T | . |
G | K | N | F | S | A | V | P | T | T | D | L | V | T | N | P | M | D | Y | L | N | P | A | H | P | L | L | L | I | S | F | G | R | S | G | N | S |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|
|
|   |   |
|
|   |   |   |   |   |   |
|   |   |   |   | . |   |   |   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |
|
|
|   |
|
|   |
|
|   |
|
Template Sequence |   |
N | R | E | V | Q | A | F | L | Q | D | L | K | G | K | T | I | D | H | V | F | F | V | A | C | G | G | S | S | A | I | X | Y | P | S | K | Y | V | F | D | R | E | S | K | S | I | N | S | D | L | Y | S | A | N | E | F | I | Q | R | N | P | V | Q | L | G | E | K | S | . |
. |
L | V | I | L | C | S | H | S | G | N | T |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |  |  |  |
| T |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T |
| S | T | T |  | . | . |  |  |  |  |  |
| S | S | S |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
9 | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | |
|
. | . | . | . | 80 | . | . | . | . | . | . |
  |
  |   |
117 | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 190 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
Query Sequence |   |
P | E | S | V | A | A | V | E | L | A | N | Q | F | V | P | E | C | Y | H | L | P | I | T | C | N | E | A | G | A | L | Y | Q | N | A | I | N | S | D | N | A | F | A | L | L | M | P | A | E | T | H | D | R | G | F | A | M | T | S | S | I | T | T | M | M | A | S | C | L | A | V | F | . |
. |
. |
. |
. |
A | P | E | T |
Query Conservation |   |
  |
|
|
|   |
|
|   |   |
|
|   |   |
|   |   |   |   |
|
|   |
|
|
|   |   |   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|
|
|   |
|   |   |
|
|   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|   |   |   |
|   |   |   |
| . | . |
|   |   |
|   |
|
|   |   |   |   |
|   |
|
|   |   |
|
| . | . | . | . | . | . |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | E | T | V | K | A | A | A | F | A | R | G | K | G | . |
. |
A | L | T | I | A | X | T | F | K | P | E | S | P | L | A | Q | E | A | Q | . |
. |
. |
. |
. |
. |
Y | V | A | Q | Y | D | W | G | D | E | A | L | A | I | N | T | N | Y | G | V | L | Y | Q | I | V | F | G | T | L | Q | V | L | E | N | N | T | K | F | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T | T | . | . |
|  |  |  |  |  |  | S |
| T | T | S |  |  |  |  |  | S | S | . | . | . | . | . | . |  |  |  |  |
|
|
| S | T | T |
|
| G | G | G | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S |
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
| . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
87 | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | |
|
. | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
  |
  |   |
192 | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | |
. | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | |
. | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | N | S | Q | T | F | R | D | V | A | D | R | C | Q | A | I | L | T | S | L | G | D | F | S | E | G | . |
V | F | G | Y | A | P | W | K | R | I | V | Y | L | G | S | G | G | L | Q | G | A | A | R | E | S | A | L | K | . |
V | L | E | L | T | A | G | K | L | A | A | F | Y | D | S | P | T | G | F | R | H | G | P | K |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |
|
|
|
|
| . |
|
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |
|   |
|
|
|   |
|   |
|   |   | . | . |   |
|   |
|   |   |   |   |   |   |
|
|   |
|
|
|   |
Template Sequence |   |
Q | A | I | E | G | L | D | Q | L | Q | A | V | Y | E | K | A | L | K | Q | E | A | D | N | A | K | Q | F | A | K | A | H | E | K | E | S | I | I | Y | T | X | A | S | G | A | N | Y | G | V | A | Y | S | Y | S | I | C | I | L | X | E | X | Q | . |
. |
W | I | H | S | H | A | I | H | A | G | E | Y | F | H | G | P | F |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| S | B |
|  |  |  |  |
| G | G | G |  |  |  |  |  |  |  |  |  | T | T | T |  |  |  |  | . | . |
|
| B |
|
|  |  |  | T | T | G | G | G | G | T | G | G |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|
|  |  |  |
|  |  |  |
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | |
|
220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . |
  |
  |   |
270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | L | V | D | D | E | T | L | V | V | V | F | V | S | S | H | P | Y | T | R | Q | Y | D | L | D | L | L | A | E | L | R | R | D | N | Q | A | M | R | V | I | A | I | A | A | E | S | S | D | I | V | A | A | G | P | H | I | I | L | P | P | S | R | H | F | I | D | V | E | Q | A | F | C | F | L | M | Y | A | Q | T | F |
Query Conservation |   |
|
|
|   |   |   |   |   |
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |
|
|
|
|   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |
|
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
Template Sequence |   |
E | I | I | D | E | S | V | P | F | I | I | L | L | G | L | D | E | . |
T | R | P | L | E | E | R | A | L | T | F | S | K | K | Y | G | K | . |
. |
K | L | T | V | L | D | A | A | S | Y | D | F | T | A | . |
. |
. |
. |
. |
. |
. |
. |
I | D | D | S | V | K | G | Y | L | A | P | L | V | L | N | R | V | L | R | S | Y |
Template Known Secondary structure |   |
G | G |
|
| T | T |
|
|  |  |  |  |  |
| S | S | T | . | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|  |  |  |  |  | G | G | G | S |
|
| T | T | . | . | . | . | . | . | . | . | S |
| T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
237 | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | |
. | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | |
|
. | . | . | . | . | . | . | . | . | 280 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . |
  |
  |   |
350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | L | M | Q | S | L | H | M | G | N | T | P | D | T | P | S | A | S | G | T | V |
Query Conservation |   |
|
|   |   |
|   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|
|   |   |
|
|   |   |   |
|   |
|
|
|   |   |
|
|
Template Sequence |   |
A | D | E | L | A | E | E | R | N | H | P | L | S | H | R | R | Y | X | W | K | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T |
|
| T | T |
|
| S | S | T | T | T | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
306 | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . |
  |