|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | E | L | V | V | V | A | I | G | G | N | S | I | I | K | D | N | A | S | Q | S | I | E | H | Q | A | E | A | V | K | A | V | A | D | T | V | L | E | M | L | A | S | D | Y | D | I | V | L | T | H | G | N | G | P | Q | V | G | L | D | L | R | R | A | E | I | A | H | K | R | E | G | L | P | L | T | P | L | A | N | C |
Query Conservation |   |
  |
|   |
|
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|
|
|
|
|
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |
|   |
|
|
|
|
|
|
|
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|   |   |
|   |   |
|   |   |   |
|   |   |
|
|
|
|
|
|   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |
Template Sequence |   |
G | K | T | L | V | I | K | Y | G | G | N | A | M | E | S | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | L | K | A | G | F | A | R | D | V | V | L | M | K | A | V | G | I | N | P | V | V | V | H | G | G | G | P | Q | I | G | D | L | L | K | R | L | S | I | E | S | H | F | I | D | G | M | R | V | T | D | A | . |
. |
Template Known Secondary structure |   |
T |
|  |  |  |  |  |  |
|
| T | T | T | T | S | S | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  | T | T |
|
|
|
| B | S | S | S | S | B |
| B |
|  | . | . |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
27 | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | |
|
  |
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | A | D | T | Q | G | G | I | G | Y | L | I | Q | Q | A | L | N | N | R | L | A | R | H | G | E | K | K | A | V | T | V | V | T | Q | V | E | V | D | K | N | D | P | G | F | A | H | P | T | K | P | I | G | A | F | F | S | D | S | Q | R | D | E | L | Q | K | A | N | P | D | W | C | F | V | E | D | A | G | R | G | Y |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | T | M | D | V | V | E | M | V | L | G | G | Q | V | N | K | D | I | V | N | L | I | N | R | H | G | G | S | A | I | G | L | T | G | K | D | A | E | L | I | R | A | K | K | L | T | V | T | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  | T | G | G | G |
|  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
95 | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. |
  |
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | R | V | V | A | S | P | E | P | K | R | I | V | E | A | P | A | I | K | A | L | I | Q | Q | G | F | V | V | I | G | A | G | G | G | G | I | P | V | V | R | T | D | A | G | D | Y | Q | S | V | D | A | V | I | D | K | D | L | S | T | A | L | L | A | R | E | I | H | A | D | I | L | V | I | T | T | G | V | E | K | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |
|
|
|
|   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|   |   |
|   |
|   |   |
|
|   |   |
|
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |
|   |
|
|   |   |
|
|   |
|
|   |   |
|   |
|   |   |
|
|   |   |
|
|
|   |
|
|
Template Sequence |   |
I | I | D | I | G | H | V | G | E | V | T | G | V | N | V | G | L | L | N | M | L | V | K | G | D | F | I | P | V | I | A | P | I | G | V | G | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
N | G | E | S | Y | N | I | N | A | D | L | V | A | G | K | V | A | E | A | L | K | A | E | K | L | M | L | L | T | N | I | A | G | L |
Template Known Secondary structure |   |
|
|
|
| B | S | B |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |
| T | . | . | . | . | . | . | . | . | . | T | S |
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |  |  | S | S | S |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
153 | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . |
  |
  |   |
242 | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | |
|
|
. | . | 300 | . | . | . | . | . | |
. | . | . | |
. | 310 | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
| . | . | . |  |  |  |  |  |  |  |  | . |
|
|
| . |
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
| . |
|
|
| . |
|
|
|
|
|
|
|
Query Sequence |   |
C | I | H | F | G | K | P | Q | Q | Q | A | L | D | R | V | D | I | A | T | M | T | R | Y | M | Q | E | G | H | F | P | P | G | S | M | L | P | K | I | I | A | S | L | T | F | L | E | Q | G | G | K | E | V | I | I | T | T | . |
. |
. |
P | E | C | L | P | A | A | L | . |
R | G | E | . |
T | G | T | H | I | I | K |
Query Conservation |   |
  |   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |
|   |   | . | . | . |   |   |   |   |   |   |   |
| . |   |
|   | . |   |
|
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
| . |
|
|
| . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   | . | . | . | . |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   | . |   |
|
|
|   |   |
|
|   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |
|
|   |
|   |   |
Template Sequence |   |
M | D | K | Q | G | Q | . |
. |
. |
. |
V | L | T | G | L | S | T | E | Q | V | N | E | L | I | A | D | G | T | I | . |
Y | G | G | M | L | P | K | I | R | C | A | L | E | A | V | Q | G | G | V | T | S | A | H | I | I | D | G | R | V | P | N | A | V | L | L | E | I | F | T | D | S | G | V | G | T | L | I | S | N |
Template Known Secondary structure |   |
B |
| T | T | S |
| . | . | . | . | B |
|
|  |  |
|  |  |  |  |  |  |  |  |  | T | T |
| S | . |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |  | T | T | S | T | T |  |  |  |  |  |  | S | S | T | T |
|
| S |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
224 | . | . | . | . | . | |
|
|
|
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | |
. | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . |
  |