|   |
49 | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | |
|
. | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | |
|
|
. | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |
| . | . |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | K | N | Y | A | G | R | P | T | A | L | T | K | C | Q | N | I | T | A | G | T | N | . |
. |
T | T | L | Y | L | K | R | E | D | L | L | H | G | G | A | H | K | T | N | Q | V | L | G | Q | A | L | L | A | K | R | M | G | K | T | . |
. |
. |
E | I | I | A | E | T | G | A | G | Q | H | G | V | A | S | A | L | A | S |
Query Conservation |   |
  |   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |
|
|   |   |
|
| . | . |   |   |
|
|
|
|   |
|   |
|
|
|
|
|
|   |
|   |
|   |
|   |   |   |
|   |   |
|   |   |   |
|   |   | . | . | . |   |   |
|   |   |   |
|
|
|
|   |
|   |
|   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   | . |
|
|
|   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |
|
|   |
|   |
|   |   |
|
|
|
|
|
|
|
|
|   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |
|   |
|   |
|   |   |
|
Template Sequence |   |
I | L | K | K | I | G | D | . |
T | P | M | V | R | I | N | K | I | G | K | K | F | G | L | K | C | E | L | L | A | K | C | E | F | F | N | A | G | G | S | V | K | D | R | I | S | L | R | M | I | E | D | A | E | R | D | G | T | L | K | P | G | D | T | I | I | E | P | T | S | G | N | T | G | I | G | L | A | L | A | A |
Template Known Secondary structure |   |
G | G | G | G | S | S |
| . |
|
|  |  |  |
|
| S |  |  |  |  | T | T |
|
| S |  |  |  |  |  |  | G | G | G | S | T | T | S | B | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |
| T | T |
|  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
| . |
|
|  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
80 | . | . | . | . | . | . | |
. | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
  |
  |   |
124 | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | L | L | G | L | K | C | R | I | Y | M | G | A | K | D | V | E | R | Q | S | P | N | V | F | R | M | R | L | M | G | A | E | V | I | P | V | H | S | G | S | A | T | L | K | D | A | C | N | E | A | L | R | D | W | S | G | S | Y | E | T | A | H | Y | M | L | G | T | A | A | G | P | H | P | Y | P | T | I | V | R | E |
Query Conservation |   |
  |   |   |
|   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|   |   |   |
|   |
|
|   |   |   |   |   |   |
| . | . | . |   |   |   |
|   |   |   |
|
|   |
|   |   |
|   |   | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
A | V | R | G | Y | R | C | I | I | V | M | P | E | K | M | S | S | E | K | . |
. |
. |
V | D | V | L | R | A | L | G | A | E | I | V | R | T | P | T | . |
. |
. |
. |
. |
. |
E | S | H | V | G | V | A | W | R | L | K | N | E | I | P | N | S | H | I | . |
. |
. |
. |
. |
L | D | Q | Y | R | N | A | S | N | P | L | A |
Template Known Secondary structure |   |
 |  |  | T |
|  |  |  |  |  |  |
| S |
|
|
|  |  |  | . | . | . |  |  |  |  |  |  | T | T |
|  |  |  |  |
|
|
| . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  | S | T | T |  |  |
| . | . | . | . | . |
|
| T | T | T |
| T |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  | . | . | . |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  | . | . | . | . | . |  |
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | |
|
|
. | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | |
|
|
|
|
|
. | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 220 | . | . | . | . |
  |
  |   |
204 | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | |
. | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | Q | R | M | I | G | E | E | T | K | A | Q | I | L | E | R | E | G | R | L | P | D | A | V | I | A | C | V | G | G | G | S | N | A | I | G | M | F | A | D | F | I | N | . |
E | T | N | V | G | L | I | G | V | E | P | G | G | H | G | I | E | T | G | E | H | G | A | P | L | K | H | G | R | V | G | I | Y | F | G | M |
Query Conservation |   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |
|   |   |
|   |   |
|
|   |
|
|   |   |
|
|   |
|   |   |   |   |
|
|   |   |   |
|   |   | . |   |   |   |
|   |   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|   |   |
|   |   |   |
|
|   |
|
|
| . | . | . | . |   |   |   |
|
|   |
|
|   |   |
|
|   |
|
|   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
H | Y | D | T | T | A | D | E | I | L | Q | Q | C | . |
. |
. |
. |
D | G | K | L | D | M | L | V | A | S | V | G | T | G | G | T | I | T | G | I | A | R | K | L | K | E | K | C | P | G | C | R | I | I | G | V | D | P | E | G | S | I | L | A | E | P | E | E | L | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  | T |  |  |  |  |  |  |  |  |  | . | . | . | . | T | T |
|
|
|  |  |  |  |  |
| S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|  |  |  |  |  |  |  | T | T |
| S |
| S | S | S | G | G | G | G | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
232 | . | . | . | . | . | . | . | 240 | . | . | . | . | |
|
|
|
. | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
283 | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | A | P | M | M | Q | T | E | D | G | Q | I | E | E | S | Y | S | I | S | A | G | L | D | F | P | S | V | G | P | Q | H | A | Y | L | N | S | T | G | R | A | D | Y | V | S | I | T | D | D | E | A | L | E | A | F | K | T | L | C | L | H | E | G | I | I | P | A | L | E | S | S | H | A | L | A | H | A | L | K | M | M |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |   |
|   |
|   |
|
|   |   |
|
|
|   |   |   |
|   |
|
|   |
|
|
|   |
|   |
|
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |
|
|   |   |
|   |   |   |
|   |   |   |
|
|
|   |
|
|
|
|
|
|
|   |
|
|
|   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | T | E | Q | T | T | Y | E | V | E | G | I | G | Y | D | F | I | P | T | V | . |
. |
. |
L | D | R | T | V | V | D | K | W | F | K | S | N | D | E | E | A | F | T | F | A | R | M | L | I | A | Q | E | G | L | L | C | G | G | S | A | G | S | T | V | A | V | A | V | K | A | A |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |
|
| S |
|
|
|
| S |
|
| S |
|
|
| S | S |
|
| T | T | . | . | . |
|
| G | G | G |
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  | G |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  | . | . | . |  |  |  |  |  |
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
295 | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | |
|
|
. | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . |
  |
  |   |
363 | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | |
|
. | . | 390 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  | . | . |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
R | E | N | P | D | K | E | Q | L | L | V | V | N | L | S | G | R | G | D | K | D | I | F | T | V | . |
. |
H | D | I | L | K | A | R | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|   |
|   |
|
|   |   |   |   | . | . |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   | . |   |   |
|   |   |
|
|
|
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |
Template Sequence |   |
Q | E | L | . |
Q | E | G | Q | R | C | V | V | I | L | P | D | S | V | R | N | Y | M | T | K | F | L | S | D | R | W | M | L | Q | K | G |
Template Known Secondary structure |   |
G | G |
| . |
| T | T |
|  |  |  |  |  |  |
| B | B | G | G | G | G | T | T | T | T | T |
|  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |
| . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
362 | . | . | |
. | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . |
  |