Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0AFD4
DateThu Jan 5 11:25:58 GMT 2012
Unique Job ID61c0d7ec9547e66b

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3rkoL_
Top template information
PDB header:oxidoreductase
Chain: L: PDB Molecule:nadh-quinone oxidoreductase subunit l;
PDBTitle: crystal structure of the membrane domain of respiratory complex i from2 e. coli at 3.0 angstrom resolution
Confidence and coverage
Confidence: 90.1% Coverage: 39%
126 residues ( 39% of your sequence) have been modelled with 90.1% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSWISPELIEILLTILKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQL
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Disorder  ?????






















































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   .........70.........80.........90.........100.........110.........120
Sequence  VADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLAFAIVPVSPGWVVADLNIGILFFL
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?
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???
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   .........130.........140.........150.........160.........170.........180
Sequence  MMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFLGLSLMGVVAQAGSFNMTDIV
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   .........190.........200.........210.........220.........230.........240
Sequence  NSQAHVWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAEQELADGYHIEYSGMKFGLFFVG
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Disorder 

??
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   .........250.........260.........270.........280.........290.........300
Sequence  EYIGIVTISALMVTLFFGGWQGPLLPPFIWFALKTAFFMMMFILIRASLPRPRYDQVMSF
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   .........310.........320.....
Sequence  GWKICLPLTLINLLVTAAVILWQAQ
Secondary structure 

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Disorder 





















???
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3rko chain L

3D model

Region: 95 - 220
Aligned: 126
Modelled: 126
Confidence: 90.1%
Identity: 17%
PDB header:oxidoreductase
Chain: L: PDB Molecule:nadh-quinone oxidoreductase subunit l;
PDBTitle: crystal structure of the membrane domain of respiratory complex i from2 e. coli at 3.0 angstrom resolution

Phyre2

PDB 2jpm chain A

3D model

Region: 51 - 81
Aligned: 31
Modelled: 31
Confidence: 28.8%
Identity: 23%
PDB header:antimicrobial protein
Chain: A: PDB Molecule:bacteriocin lactococcin-g subunit beta;
PDBTitle: lactococcin g-b in tfe

Phyre2

PDB 1xn8 chain A

3D model

Region: 212 - 246
Aligned: 35
Modelled: 35
Confidence: 24.2%
Identity: 14%
Fold: Hypothetical protein YqbG
Superfamily: Hypothetical protein YqbG
Family: Hypothetical protein YqbG

Phyre2

PDB 3rko chain N

3D model

Region: 95 - 283
Aligned: 173
Modelled: 189
Confidence: 16.8%
Identity: 14%
PDB header:oxidoreductase
Chain: N: PDB Molecule:nadh-quinone oxidoreductase subunit n;
PDBTitle: crystal structure of the membrane domain of respiratory complex i from2 e. coli at 3.0 angstrom resolution

Phyre2

PDB 1q2i chain A

3D model

Region: 61 - 70
Aligned: 10
Modelled: 10
Confidence: 10.3%
Identity: 30%
PDB header:antitumor protein
Chain: A: PDB Molecule:pnc27;
PDBTitle: nmr solution structure of a peptide from the mdm-2 binding2 domain of the p53 protein that is selectively cytotoxic to3 cancer cells

Phyre2

PDB 1jb0 chain L

3D model

Region: 140 - 246
Aligned: 85
Modelled: 87
Confidence: 6.7%
Identity: 20%
Fold: Photosystem I reaction center subunit XI, PsaL
Superfamily: Photosystem I reaction center subunit XI, PsaL
Family: Photosystem I reaction center subunit XI, PsaL

Phyre2

PDB 2dbh chain A

3D model

Region: 36 - 63
Aligned: 22
Modelled: 22
Confidence: 5.8%
Identity: 36%
PDB header:signaling protein
Chain: A: PDB Molecule:tumor necrosis factor receptor superfamily
PDBTitle: solution structure of the carboxyl-terminal card-like2 domain in human tnfr-related death receptor-6

Phyre2
1

c3rkoL_
2

c2jpmA_
3

d1xn8a_
4

c3rkoN_
5

c1q2iA_
6

d1jb0l_
7

c2dbhA_



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3rkoL_



90.1 17 PDB header:oxidoreductase
Chain: L: PDB Molecule:nadh-quinone oxidoreductase subunit l;
PDBTitle: crystal structure of the membrane domain of respiratory complex i from2 e. coli at 3.0 angstrom resolution
2c2jpmA_



28.8 23 PDB header:antimicrobial protein
Chain: A: PDB Molecule:bacteriocin lactococcin-g subunit beta;
PDBTitle: lactococcin g-b in tfe
3d1xn8a_



24.2 14 Fold:Hypothetical protein YqbG
Superfamily:Hypothetical protein YqbG
Family:Hypothetical protein YqbG
4c3rkoN_



16.8 14 PDB header:oxidoreductase
Chain: N: PDB Molecule:nadh-quinone oxidoreductase subunit n;
PDBTitle: crystal structure of the membrane domain of respiratory complex i from2 e. coli at 3.0 angstrom resolution
5c1q2iA_



10.3 30 PDB header:antitumor protein
Chain: A: PDB Molecule:pnc27;
PDBTitle: nmr solution structure of a peptide from the mdm-2 binding2 domain of the p53 protein that is selectively cytotoxic to3 cancer cells
6d1jb0l_



6.7 20 Fold:Photosystem I reaction center subunit XI, PsaL
Superfamily:Photosystem I reaction center subunit XI, PsaL
Family:Photosystem I reaction center subunit XI, PsaL
7c2dbhA_



5.8 36 PDB header:signaling protein
Chain: A: PDB Molecule:tumor necrosis factor receptor superfamily
PDBTitle: solution structure of the carboxyl-terminal card-like2 domain in human tnfr-related death receptor-6

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0