|   |
23 | . | . | . | . | . | . | 30 | |
. | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | |
|
|
|
. | . | . | 50 | . | . | . | . | . | . | . | |
|
|
|
. | . | 60 | . | . | . | . | . | . | . | . | . | 70 | |
. | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |
|  |  |  |  |  |  |  |  |
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |
|
|
| . |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
|
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|
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| . |
. |
. |
. |
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|
| . |
. |
. |
. |
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| . |
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|
|
Query Sequence |   |
E | F | G | C | P | V | W | V | . |
Y | D | A | Q | I | I | R | R | Q | I | A | A | L | K | Q | F | . |
. |
. |
. |
D | V | V | R | F | A | Q | K | A | C | S | . |
. |
. |
. |
N | I | H | I | L | R | L | M | R | E | Q | G | V | . |
K | V | D | S | V | S | L | G | E | I | E | R | A | L | A | A | G | Y | N | P | Q | T |
Query Conservation |   |
  |   |
|
|
|   |   |
| . |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |   | . | . | . | . |   |   |
|   |
|
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|
|   | . | . | . | . |   |   |   |
|
|   |   |
|   |   |   |
|   | . |
|   |
|
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|
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
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|
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|
|
| . |
|
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|
| . | . | . | . |
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|
| . | . | . | . |
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| . |
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|
|
|
| . | . |
Template Conservation |   |
  |   |   |
|   |
|   |   |
|
|
|
|   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
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|
|   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |
|
|   |   |   |
|
|   |   |
|
|   |   |
|   |   |   | . | . |
Template Sequence |   |
D | F | H | R | D | T | W | A | E | V | D | L | D | A | I | Y | D | N | V | E | N | L | R | R | L | L | P | D | D | T | H | I | M | A | V | V | K | A | N | A | Y | G | H | G | D | V | Q | V | A | R | T | A | L | E | A | G | A | S | R | L | A | V | A | F | L | D | E | A | L | A | L | R | E | K | G | I | E | A | . |
. |
Template Known Secondary structure |   |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| T | T | S |  |  |  |  |  |
|  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  | S | S |  |  |  |  |  |  |  |  |  | T | T |
|
| S | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
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|
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|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . |
Template SS confidence |   |
|
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  |   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | |
|
  |
  |   |
93 | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | |
. |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
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|
|  |  |  |  |  |  |
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  | . |  |
Query SS confidence |   |
|
|
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|
|
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|
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|
|
|
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|
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|
|
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|
|
|
|
|
|
| . |
|
Query Sequence |   |
H | P | D | D | I | V | F | T | A | D | V | I | D | Q | A | T | L | E | R | V | S | E | L | Q | I | P | V | N | A | G | S | V | D | M | L | D | Q | L | G | Q | V | S | P | G | H | R | V | W | L | R | V | N | P | G | F | G | H | G | H | S | Q | K | T | N | T | G | G | E | N | S | K | H | G | I | W | Y | T | D | . |
L |
Query Conservation |   |
  |   |   |   |
|
|   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |
|   |
|   |
|
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   | . |   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
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|
|
| . | . |
|
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|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . |
|
Template Conservation |   |
. | . | . |   |
|
|
|
|   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |
|
|
|
|
|   | . | . | . | . | . | . | . | . | . | . |
|   |
|   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
P | I | L | V | L | G | A | S | . |
R | P | A | D | A | A | L | A | A | Q | Q | R | I | A | L | T | V | F | R | S | D | W | L | E | E | A | S | A | L | Y | S | G | P | F | P | I | . |
. |
H | F | H | L | M | D | T | G | M | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | L | G | V | K | D | E | E | E | T |
Template Known Secondary structure |   |
. | . | . |
|  |  |  |
| S |
|
| . |
| G | G | G |  |  |  |  |  |  | T | T |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | T | T |
|
|
| S | S |
|  | . | . |  |  |  |
|
|
| S | S |
|
| . | . | . | . | . | . | . | . | . | . | S | S | S |
|
| S |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . |  |  |  |  |  |
|
|
| . |
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  | . | . |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
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|
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|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
  |   |
|
|
|
81 | . | . | . | . | . | . | . | |
. | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | |
|
. | . | . | . | . | 130 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 140 | . | . | . | . |
  |
  |   |
172 | . | . | . | . | . | . | |
. | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | |
|
. | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  | . |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
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|
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|
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|
|
Query Sequence |   |
P | A | A | L | D | V | I | . |
Q | R | H | H | L | Q | L | V | G | I | H | M | H | I | G | S | G | . |
. |
V | D | Y | A | H | L | E | Q | V | C | G | A | M | V | R | Q | V | I | E | F | G | Q | D | L | Q | A | I | S | A | G | G | G | L | S | V | P | Y | Q | Q | G | E | E | A | V | D | T | E | H | Y | Y | G | L | W |
Query Conservation |   |
  |   |   |   |   |   |   | . |   |   |   |   |
|   |
|   |
|
|
|   |
|   |
|
|   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
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|
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|
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|
| . | . |
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|
|
|
| . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |
|   |   |   |
|   |   |   |   |   |
|   |
|   |
|
|   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |
|   |   |
|   |   |   |   |
| . | . | . | . | . | . | . | . | . |
Template Sequence |   |
K | R | I | V | A | L | I | E | R | H | P | H | F | V | L | E | G | L | Y | T | H | F | A | T | A | D | E | V | N | T | D | Y | F | S | Y | Q | Y | T | R | F | L | H | M | L | E | W | L | P | S | R | P | P | L | V | H | C | A | N | S | A | A | S | L | R | F | P | D | R | T | F | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | S | T | T |  |  |  |  |  |  |  |
|
|
| S | S | T | T | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S | S |
|
| S |  |  |  |
|
|
|  |  |  |  |  |  |
| G | G | G |
| T | T | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|  |  |
|
|
|
| . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
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|
|
|
  |   |
146 | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | |
|
|
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|
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|
|
  |
  |   |
249 | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | |
|
|
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|
|
. | . | . | 280 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
290 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
N | A | A | R | E | Q | I | A | R | H | L | G | H | P | V | K | L | E | I | E | P | G | R | F | L | V | A | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | G | V | L | I | T | Q | V | R | S | V | K | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
M | G | S | R | H | F | V | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
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|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
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Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
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| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
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Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
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|   |
|   |   |
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|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
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|   |   |
|   |
|   |
|   |   |
|   |   |   |   |   |
|   |   |
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|   |   |   |   |   |   |   |   |   |   |
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Template Sequence |   |
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M | V | R | F | G | I | A | M | Y | G | L | A | P | S | P | G | I | K | P | L | L | P | Y | P | L | K | E | A | F | S | L | H | S | R | L | V | H | V | K | K | L | Q | P | G | E | K | V | S | Y | G | A | T | Y | T | A | Q | T | E | E | W | I | G | T |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
| G | G | G | G | T |
|
| S |
| S | T | T | G | G | G |
| S | S |
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|  |  |  |  |  |  |
|
|  |  |  |  |  |
| T | T |
|  |  | S | G | G | G |
|  |  |
|
| S | S |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
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|  |  |
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|  |  |  |
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|  |  |  |  |
Template SS confidence |   |
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  |   |
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217 | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . |
  |
  |   |
298 | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | |
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Predicted Secondary structure |   |
 |  |
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|  |  |  |  |
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|  |  |  |  |  |  |  |  |
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|  |  |  |  |  | . | . | . | . |
Query SS confidence |   |
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| . |
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. |
Query Sequence |   |
V | D | A | G | F | N | D | L | M | R | P | A | M | Y | G | S | Y | H | H | I | S | A | L | A | A | D | G | R | S | L | E | H | A | P | T | V | E | T | V | V | A | G | P | L | C | E | S | G | D | V | F | T | Q | Q | E | G | G | N | V | E | T | R | A | L | P | E | V | K | A | G | D | Y | L | V | L | H | . |
. |
. |
. |
Query Conservation |   |
  |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
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|   |
|   |   |
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|   |
|   |
|   | . | . | . | . |
Alig confidence |   |
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| . | . | . | . | . | . | . | . | . | . | . | . | . |
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| . | . |
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| . | . | . | . |
Template Conservation |   |
|   |
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|   |   |
|   |   |
|   |   |   |
|   |
| . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |
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|   |
|   |
| . | . |
|   |   |   |
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|   | . | . | . | . | . | . | . | . |   |
|   |
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|   |
|   |
|   |
|   |   |   |
Template Sequence |   |
I | P | I | G | Y | A | D | G | W | L | R | R | L | Q | H | F | H | V | L | V | . |
. |
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D | G | Q | K | A | P | I | V | G | R | I | C | M | . |
. |
D | Q | C | M | I | R | L | P | G | . |
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. |
P | L | P | V | G | T | K | V | T | L | I | G | R | Q | G |
Template Known Secondary structure |   |
 | S |
|
| G | G | G | T |
|
| G | G | G | G | G |
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T |  |  |  |  |  |  | S |
|
|
| S | . | . | S |
|  |  |  |  |  | S | S | . | . | . | . | . | . | . | . |
|
|
| T | T |
|  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |
|
|
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|
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|
|  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |
|
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|
| . | . |
|
|  |  |  |  |
|
|
| . | . | . | . | . | . | . | . |
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|  |  |  |  |  |
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|
Template SS confidence |   |
|
|
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  |   |
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | |
|
|
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|
300 | . | . | . | . | . | . | . | . | . | 310 | . | . | |
|
. | . | . | . | . | . | . | 320 | . | |
|
|
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|
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|
. | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . |
  |
  |   |
|
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|
374 | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
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Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | T | G | A | Y | G | A | S | M | S | S | N | Y | N | S | R | P | L | L | P | E | V | L | F | D | N | G | Q | A | R | L | I | R | R | R |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|
|   |   |
|   |   |   |   |
|
|   |   |   |   |
|   |   |
|   |
|   |   |
|   |   |   |   |
|
|
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
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|
|
| . | . | . | . |
|
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|
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|
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|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|
|
|
|   |   |
|   | . | . | . | . |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | E | V | I | S | I | D | D | V | A | R | H | L | E | T | I | N | Y | E | V | P | C | T | I | S | . |
. |
. |
. |
Y | R | V | P | R | I | F | F | R | H | K | R | I | M | E | V | R | N | A |
Template Known Secondary structure |   |
T |  |  |  |
|  |  |  |  |  |  |  |  | T | S |
| T | T |  |  |  |  |  | S |
| . | . | . | . | T | T | S |
|  |  |  |  |  | T | T |  |  |  |  |  |  |
| T |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
| . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
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|
  |   |
337 | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | |
|
|
|
. | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 |
  |