|   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | |
. | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | |
. | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | L | N | L | V | Y | I | Y | G | E | S | L | E | R | T | Y | F | D | N | E | A | F | P | . |
D | L | T | P | E | L | G | A | L | K | N | E | G | L | D | F | S | H | T | Q | Q | L | P | G | T | D | Y | T | I | A | G | M | V | A | S | Q | C | G | . |
I | P | L | F | A | P | F | E | G | N | A | S | A | S | V | S | S |
Query Conservation |   |
|
|
|
|
|
|
|   |
|
|
|
|
|   |   |   |   |
|   |   |   |   |   | . |   |
|
|
|
|
|   |
|
|   |
|
|   |
|   |
|   |
|   |   |   |   |
|   |
|   |   |
|
|   |
|
|   |
|   |
|
|
| . |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|   |
|   |   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |
|
|
|
|
|   |
|
|   |   |
|   |   |
|   |
|   | . | . |   |   |   |   |   |   |
|   |
|
|   |   |
|
|
|
|
|   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Q | P | N | L | V | I | I | M | A | D | D | L | G | Y | G | D | L | A | T | Y | G | H | Q | I | V | K | T | P | N | I | D | R | L | A | Q | E | G | V | K | F | T | D | Y | . |
. |
Y | A | P | A | P | L | S | S | P | S | R | A | G | L | L | T | G | R | M | P | F | R | T | G | I | R | S | W | I | P | S | G | K | D | V |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  | S | S |
|
| T | T | S | S | G | G | G | T |
| S | S |
|
|
|  |  |  |  |  |  |  |  | T | S |  |  |  | S | S |  | . | . |  |
| S | S | S | S |  |  |  |  |  |  |  |  |  |  | T | S |
| G | G | G | G | T |
| S | S |
|
|
| T | T | S | S |
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  | . | . |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
42 | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | |
|
. | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . |
  |
  |   |
239 | 240 | . | |
. | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | |
|
|
. | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
| . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
F | F | P | . |
Q | N | I | C | L | G | D | I | L | K | N | S | G | Y | Q | N | Y | F | V | Q | G | . |
. |
. |
A | N | L | R | F | A | G | K | D | V | F | L | K | S | H | G | F | D | H | L | Y | G | S | E | E | L | K | S | V | V | A | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |
| . |   |   |   |
|
|   |
|
|
|
|   |   |
|
|   |
|   |
|
|   |
| . | . | . |   |   |   |   |
|   |
|
|   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | L | G | R | N | E | L | T | I | A | N | L | L | K | A | Q | G | Y | D | T | A | M | M | G | K | L | H | L | N | A | G | G | D | R | T | D | Q | P | Q | A | Q | D | M | G | F | D | Y | S | L | A | N | T | A | G | F | V | T | D | A | T | L | D | N | A | K | E | R | P | R | Y | G | M | V | Y | P | T | G | W | L | R |
Template Known Secondary structure |   |
| S |
| T | T |
|
|
|  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |  |  |
|
| S | S | S |
| T | T |
| T | T | S |
|
| T | T | T | T | T |
| S |  |  |  |  |  |
| S | S | S |
|
|
|  |  |  |  | T |
|
| S | S | S |
| B |
|
|
|
|
|
| S |
|  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
295 | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 350 | . | . | . |
Predicted Secondary structure |   |
. | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
P | H | Y | R | N | D | W | G | F | Y | D | D | T | V | L | D | E | A | W | K | K | F | E | E | L | S | R | S | G | Q | R | F | S | L | F | T | L | T | V | D | T | H | H | P | D | G | F | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | R | T | C | N | R | K | K | Y | D | F |
Query Conservation |   |
. | . |   |   |   |   |   |   |
|
|
|   |
|
|   |
|
|   |   |
|   |   |   |
|   |   |
|
|
|
|   |
|
|
|
|   |   |
|
|
|   |
|
|
|   |
|
|   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   | . |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
N | G | Q | P | T | P | R | A | D | K | M | S | G | E | Y | V | S | S | E | V | V | N | W | L | D | N | K | . |
K | D | S | K | P | F | F | L | Y | V | A | F | T | E | V | H | S | P | L | A | S | P | K | K | Y | L | D | M | Y | S | Q | Y | M | S | A | Y | Q | K | Q | H | P | D | L | F | Y | G | D | W | A | D | K | P |
Template Known Secondary structure |   |
T | T |  |  |
|
|
|
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| . |
| S | S |
|
|  |  |  |  |  |  |
|
| T | T | S | S | S |
|
|
|
|  |  |  |  |  | T | T | G | G | G | B |
|  |  |  |  |  | S | T | T | B |
| G | G | G |
| T | T | S |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | |
. | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . |
  |
  |   |
354 | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 410 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | G | K | P | N | Q | S | F | S | A | V | S | C | S | Q | E | N | I | A | T | F | I | N | K | I | K | A | S | P | W | F | K | D | T | V | I | V | V | S | S | D | H | L | A | M | N | N | T | A | W | K | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | N | K | Q | D | R | N | N | L | F |
Query Conservation |   |
  |   |   |   |
|   |
|
|
|
|
|   |
|
|
|   |   |
|
|   |
|
|   |   |
|
|
|
|   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |
|
|   |   |
|   |   |   |
|   |   |
|
|
|
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|
|
|
Template Sequence |   |
W | R | G | V | G | E | Y | Y | A | N | I | S | Y | L | D | A | Q | V | G | K | V | L | D | K | I | K | A | M | G | E | E | D | N | T | I | V | I | F | T | S | D | N | G | P | V | T | R | E | A | R | K | V | Y | E | L | N | L | A | G | E | T | D | G | L | R | G | R | K | D | N | L | W | E | G | G | I | R | V | P | A |
Template Known Secondary structure |   |
|
| B | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| G | G | G |  |  |  |  |  |  |  | S | S |
|
|
|
| S |
|
|
| S | G | G | G | T | T |
|
|
|
|
| T | T |
| S |
|
| T | T |
|
| S |  |  |  |  | B |
|
|  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
279 | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . |
  |
  |   |
416 | . | . | . | 420 | . | |
. | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | |
|
|
. | 450 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
| . |
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | V | I | R | G | D | . |
K | P | Q | Q | E | T | L | A | V | K | R | N | T | M | D | N | G | A | T | V | L | D | I | L | G | G | D | . |
. |
. |
N | Y | L | G | L | G | R | S | S | L |
Query Conservation |   |
  |
|
|   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|
|
|
|   |
|
|
|   |
| . | . | . |   |   |
|
|
|
|
|   |
|
|
Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |
|
|
|
|   |
|   |
|   |   |   |
|   |   |   |   |   |
|
|   |
|
|   |
Template Sequence |   |
I | I | K | Y | G | K | H | L | P | Q | G | M | V | S | D | T | P | V | Y | G | L | D | W | M | P | T | L | A | K | M | M | N | F | K | L | P | T | D | R | T | F | D | G | E | S | L | V |
Template Known Secondary structure |   |
 |  |  |  | T | T | S | S |
| T | T |  |  |  |
| S |
|  |  | G | G | G |  |  |  |  |  |  |  |  |  | T |
|
|
|
| S | S | S |
|
|
|
|
|
|
|  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
359 | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . |
  |