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Job DescriptionP39401
Confidence99.74%DateThu Jan 5 12:00:36 GMT 2012
Rank20Aligned Residues256
% Identity12%Templatec2xrgA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor
Resolution3.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   151........160.........170.........180.........190.........200.........210.........220.........230
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Query Sequence  KEPSKTIPDPKLNLVYIYGESLERTYFDNEAFPDLTPELGALKNEGLDFSHTQQLPGTDYTIAGMVASQCGIPLFAPFEG
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Template Sequence  KVPECPAGFVRPPLIIFSVDGFRASYMKKG. . SKVMPNIEKLRSCGTHAPYMRP. VYPTKTFPNLYTLATGLYPESHGIV
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S



TT
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T

GGGGGS
..TTTSS
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S
S
S

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   152.......160.........170.........180. ........190.........200... ......210.........220........
 
   231 ........240.........250.........260.........270.........280.........290.....
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Query Sequence  N. . . . . . . . . . . . . . . ASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKSHGFDHLYGSEELKSVVADP
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Template Sequence  GNSMYDPVFDASFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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SSTTTT
SSSSGGG
TTS

S

TTT

B





TT..............................
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   229230.........240.........250.........260.........270........
 
   296...300.........310.........320.........330...... ...340.........350.........360.........370..
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Query Sequence  HYRNDWGFYDDTVLDEAWKKFEELSRSGQRFSLFTLTVDTH. . . HPDGFISRTCNRKKYDFDGKPNQSFSAVSCSQENIA
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Template Sequence  . . . . . . . IPHERRILTILQWLSLP. DNERPSVYAFYSEQPDFSGHKYGPFGP. . . . . . . . . . . . . . EMTNPLREIDKTVG
Template Known Secondary structure  .......S
TTS
.TTT

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G..............GG
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   279280.........290..... ....300.........310.........320.. .......330......
 
   373......380.........390.........400
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Query Sequence  TFINKIKASPWFKDTVIVVSSDHLAMNN. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  QLMDGLKQLRLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRAKYDPKTIIAALTCKKPDQHFKP
Template Known Secondary structure  TT
TTT
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SSSGGGT
S

TT
BS


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STT

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   337..340.........350.........360.........370.........380.........390.........400.........410......
 
   401........410.........420.........430.........440..
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TAWKYLNKQDRNNLFFVIRGDKPQQETLAVKRNTMDNGATVL
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Template Sequence  YMKQHLPKRLHYANNRRIEDIHLLVDRRWHVARKPFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVP. PFENIELYNVMC
Template Known Secondary structure  GGGS
GGG


SSTTS
S
TT
S





S
TT
GGG
B
SSSB
SS
B

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GGG
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   423......430.........440.........450.........460.........470.........480......... 490.........500.
 
   443... ...450.........460..
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Query Sequence  DILG. . . . . GDNYLGLGRSSLSGQS
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Template Sequence  DLLGLKPAPNNGTHGSLNHLLRTNT
Template Known Secondary structure  T



S
SS
TTTTGGGBSS

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   514.....520.........530........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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