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Job DescriptionP0A6B7
Confidence100.00%DateWed Jan 25 15:20:14 GMT 2012
Rank8Aligned Residues349
% Identity16%Templatec3e9kA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex
Resolution1.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   5....10.........20.........30.........40.........50.........60.........70.........80....
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Query Sequence  IYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFGWQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIK
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Template Sequence  IYFLGNSLGLQPKMVKTYLEEELDKWAKIA. . AYGHEVGKRPWITGDESIVGLMKDIVGANEKEIALMNALTVNLHLLML
Template Known Secondary structure 
BTTTS

B
TTG..GGGGTSSSS
GGGTTGGGT

GGG
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   6970.........80.........90........ .100.........110.........120.........130.........140......
 
   85....90.........100.........110...... ...120.........130.........140. ........150.....
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Query Sequence  GAANFYQKKGKHIITSKTEHKAVLDTCRQLER. . . . . . EGFEVTYLAPQRNGIIDLKELEAAM. . . RDDTILVSIMHVNN
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Template Sequence  SFFKPT. PKRYKILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHF
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.SSS
TT

TT




TT
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GGGSB
T
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   147..150.. .......160.........170.........180.........190.........200.........210.........220.....
 
   156...160.........170.........180.........190.........200........ .210.........220.........230...
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Query Sequence  EIGVVQDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIY. . GPKGIGALYVRRKPRVRIEAQMHGG
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Template Sequence  YTGQHFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVGW
Template Known Secondary structure  TT
BB

TT

TTTTTTS


T


SSSTT


TT



GGGTTTS

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G
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   226...230.........240.........250.........260.........270.........280.........290.........300.....
 
   234.. ...240.........250....... ..260.........270.........280. ........290...
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Query Sequence  GHE. . . . . . . . . . . . . . . . . . RGMRSGTLPVHQIVGMGEAYR. IAKEEMATEMERLRGLRNRLWNGI. KDIEEVYLNGDL
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Template Sequence  FGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEYLIKHNYGVVNIITPS
Template Known Secondary structure  GGB
TT

S


B
SSGGGG

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   306...310.........320.........330.........340.........350.........360.........370.........380.....
 
   294... ..300.........310.........320.........330.........340.........350....... ..360.........370.
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Query Sequence  EHGA. PNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFSL. GRFTTEEEIDYTIE
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Template Sequence  HVEERGCQLTITFSV. PNKDVFQELEKRGVVC. . . . . . . . . . . . . . . . . . . . . DKRNPNGIRVAPVPLYNSFHDVYKFTN
Template Known Secondary structure  SGGGB
S


.TT

TTT
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TTT

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   395....400......... 410.........420..... ....430.........440.........450..
 
   372......
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Query Sequence  LVRKSIG
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Template Sequence  LLTSILD
Template Known Secondary structure  T
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   453......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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