|   |
46 | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | |
|
|
. | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |
|
|
|  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | W | Q | R | L | E | L | P | D | G | D | F | V | D | L | A | W | S | E | N | P | A | Q | A | Q | H | K | P | R | L | V | V | F | H | G | L | E | G | S | L | N | S | P | Y | A | H | G | L | V | E | A | A | Q | . |
. |
. |
K | R | G | W | L | G | V | V | M | H | F | R | G | C | S | G | E | P | N | R | M | H | R | I |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   | . | . | . |   |   |
|   |   |
|
|   |   |
|   |
|
|   |
|   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |
| . | . | . | . |   |
|
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |
| . | . |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|   |
|   |
|   |   |   |   |   |   |   |
Template Sequence |   |
K | F | V | K | I | N | E | K | G | F | S | D | F | N | I | H | Y | N | E | A | G | . |
. |
. |
. |
N | G | E | T | V | I | M | L | H | G | G | G | P | G | A | G | G | W | . |
. |
S | N | Y | Y | R | N | V | G | P | F | V | D | A | G | Y | R | V | I | L | K | D | S | P | G | F | N | K | S | D | A | V | V | M | D | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
| S | S |  |  |  |  |  |
|
|
| S | T | T |
|
|  |  | . | . |  |  |  | T | T | T |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
|
| T | T | S | T | T | S |
|
|
|
|
| S | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
11 | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | |
|
|
|
. | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | |
|
50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
  |
  |   |
123 | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | H | S | G | E | T | E | D | A | S | W | F | L | R | W | L | Q | R | E | F | G | H | A | P | T | A | A | V | G | Y | S | L | G | G | N | M | L | A | C | L | L | A | K | E | G | N | D | L | P | V | D | A | A | V | I | V | S | A | P | F | M | L | E | A | C | S | Y | H | M | E | K | G | F | S | R | V | Y | Q | R | Y |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |
|
|   |
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Q | . |
. |
. |
R | G | L | V | N | A | R | A | V | K | G | L | M | D | A | L | D | I | D | R | A | H | L | V | G | N | A | M | G | G | A | T | A | L | N | F | A | L | E | Y | P | D | . |
. |
R | I | G | K | L | I | L | M | G | P | G | G | L | G | P | S | M | F | A | P | M | P | M | E | G | I | K | L | L | F | K | L |
Template Known Secondary structure |   |
| . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | . | . | G |  |  |  |  |  |  |  | S |
| S |
|
|
|
|
| S | S | S |
| S | S |
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
85 | |
|
|
. | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | |
|
. | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . |
  |
  |   |
203 | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | L | N | L | L | K | A | N | A | A | R | K | L | A | A | Y | P | G | T | L | P | I | N | L | A | Q | L | K | S | V | R | R | I | R | E | F | D | D | L | I | T | A | R | I | H | G | Y | A | D | A | I | D | Y | Y | R | Q | C | S | A | M | P | M | L | N | R | I | A | K | P | T | L | I | I | H | A | K | D | D | P | F |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|
|
|
|   |
|   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |
|   |   |
Template Sequence |   |
Y | A | E | P | S | Y | E | T | L | K | Q | M | L | Q | V | F | L | Y | D | Q | S | L | I | T | E | E | L | L | Q | G | R | W | E | A | I | Q | R | Q | P | E | H | L | K | N | F | L | I | S | A | Q | K | A | P | L | S | T | W | D | V | T | A | R | L | G | E | I | K | A | K | T | F | I | T | W | G | R | D | D | R | F |
Template Known Secondary structure |   |
 |  | S |
|
|  |  |  |  |  |  |  |  |  |  |  |
| S |
| G | G | G |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| G | G | G | G |
|
| G | G | G | G | G | G |
|
| S |
|  |  |  |  |  |  | T | T |
| S | S |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . |
  |
  |   |
283 | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | D | H | Q | V | I | P | K | P | E | S | L | P | P | Q | V | E | Y | Q | L | T | E | H | G | G | H | V | G | F | I | G | G | T | L | L | H | P | Q | M | W | L | E | S | R | I | P | D | W | L | T | T |
Query Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |
|   |
|   |   | . | . | . | . | . |   |   |   |   |
|   |   |
|
|   |   |
Template Sequence |   |
V | P | L | D | H | G | L | K | L | L | W | N | I | D | D | A | R | L | H | V | F | S | K | C | G | H | W | A | Q | W | E | H | A | D | E | . |
. |
. |
. |
. |
F | N | R | L | V | I | D | F | L | R | H |
Template Known Secondary structure |   |
S |
| T |  |  |  |  |  |  |  |  |  | S | S | S |  |  |  |  |  |  | S | S |
|
| S |
|  |  |  |  | T |  |  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|  |  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 280 | . | . | . | . | . |
  |